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Items: 16

1.

Dihydrostreptomycin Directly Binds to, Modulates, and Passes through the MscL Channel Pore.

Wray R, Iscla I, Gao Y, Li H, Wang J, Blount P.

PLoS Biol. 2016 Jun 9;14(6):e1002473. doi: 10.1371/journal.pbio.1002473. eCollection 2016 Jun.

2.

Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations.

Iscla I, Wray R, Eaton C, Blount P.

PLoS One. 2015 Sep 14;10(9):e0137994. doi: 10.1371/journal.pone.0137994. eCollection 2015.

3.

Mechanical coupling of the multiple structural elements of the large-conductance mechanosensitive channel during expansion.

Li J, Guo J, Ou X, Zhang M, Li Y, Liu Z.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10726-31. doi: 10.1073/pnas.1503202112. Epub 2015 Aug 10.

4.

Electrostatics at the membrane define MscL channel mechanosensitivity and kinetics.

Zhong D, Blount P.

FASEB J. 2014 Dec;28(12):5234-41. doi: 10.1096/fj.14-259309. Epub 2014 Sep 15.

5.

Dynamics of protein-protein interactions at the MscL periplasmic-lipid interface.

Zhong D, Yang LM, Blount P.

Biophys J. 2014 Jan 21;106(2):375-81. doi: 10.1016/j.bpj.2013.12.006.

6.

Improving the Design of a MscL-Based Triggered Nanovalve.

Iscla I, Eaton C, Parker J, Wray R, Kovács Z, Blount P.

Biosensors (Basel). 2013;3(1):171-84. doi: 10.3390/bios3010171.

7.

Structural investigation of MscL gating using experimental data and coarse grained MD simulations.

Deplazes E, Louhivuori M, Jayatilaka D, Marrink SJ, Corry B.

PLoS Comput Biol. 2012;8(9):e1002683. doi: 10.1371/journal.pcbi.1002683. Epub 2012 Sep 20.

8.

The dynamics of protein-protein interactions between domains of MscL at the cytoplasmic-lipid interface.

Iscla I, Wray R, Blount P.

Channels (Austin). 2012 Jul-Aug;6(4):255-61. doi: 10.4161/chan.20756. Epub 2012 Jul 1.

9.

Sensing and responding to membrane tension: the bacterial MscL channel as a model system.

Iscla I, Blount P.

Biophys J. 2012 Jul 18;103(2):169-74. doi: 10.1016/j.bpj.2012.06.021. Epub 2012 Jul 17. Review.

10.

The MscS and MscL families of mechanosensitive channels act as microbial emergency release valves.

Booth IR, Blount P.

J Bacteriol. 2012 Sep;194(18):4802-9. doi: 10.1128/JB.00576-12. Epub 2012 Jun 8. Review.

11.

Three routes to modulate the pore size of the MscL channel/nanovalve.

Yang LM, Wray R, Parker J, Wilson D, Duran RS, Blount P.

ACS Nano. 2012 Feb 28;6(2):1134-41. doi: 10.1021/nn203703j. Epub 2012 Jan 6.

12.

The oligomeric state of the truncated mechanosensitive channel of large conductance shows no variance in vivo.

Iscla I, Wray R, Blount P.

Protein Sci. 2011 Sep;20(9):1638-42. doi: 10.1002/pro.686. Epub 2011 Jul 19.

13.

S. aureus MscL is a pentamer in vivo but of variable stoichiometries in vitro: implications for detergent-solubilized membrane proteins.

Dorwart MR, Wray R, Brautigam CA, Jiang Y, Blount P.

PLoS Biol. 2010 Dec 7;8(12):e1000555. doi: 10.1371/journal.pbio.1000555.

14.

An in vivo screen reveals protein-lipid interactions crucial for gating a mechanosensitive channel.

Iscla I, Wray R, Blount P.

FASEB J. 2011 Feb;25(2):694-702. doi: 10.1096/fj.10-170878. Epub 2010 Nov 10.

15.

An improved open-channel structure of MscL determined from FRET confocal microscopy and simulation.

Corry B, Hurst AC, Pal P, Nomura T, Rigby P, Martinac B.

J Gen Physiol. 2010 Oct;136(4):483-94. doi: 10.1085/jgp.200910376.

16.

Mechanosensitivity of ion channels based on protein-lipid interactions.

Yoshimura K, Sokabe M.

J R Soc Interface. 2010 Jun 6;7 Suppl 3:S307-20. doi: 10.1098/rsif.2010.0095.focus. Epub 2010 Mar 31. Review.

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