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Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis.

Reißig S, Tang Y, Nikolaev A, Gerlach K, Wolf C, Davari K, Gallus C, Masri J, Mufazalov IA, Neurath MF, Wunderlich FT, Schattenberg JM, Galle PR, Weigmann B, Waisman A, Glasmacher E, Hövelmeyer N.

Nat Commun. 2017 Apr 28;8:15069. doi: 10.1038/ncomms15069.


Diacylglycerol Kinases in T Cell Tolerance and Effector Function.

Chen SS, Hu Z, Zhong XP.

Front Cell Dev Biol. 2016 Nov 10;4:130. eCollection 2016. Review.


Late stages of T cell maturation in the thymus involve NF-κB and tonic type I interferon signaling.

Xing Y, Wang X, Jameson SC, Hogquist KA.

Nat Immunol. 2016 May;17(5):565-73. doi: 10.1038/ni.3419. Epub 2016 Apr 4.


T cell receptor signalling in the control of regulatory T cell differentiation and function.

Li MO, Rudensky AY.

Nat Rev Immunol. 2016 Apr;16(4):220-33. doi: 10.1038/nri.2016.26. Review.


SHARPIN controls the development of regulatory T cells.

Redecke V, Chaturvedi V, Kuriakose J, Häcker H.

Immunology. 2016 Jun;148(2):216-26. doi: 10.1111/imm.12604. Epub 2016 Apr 12.


Hypoxia-inducible factors in T lymphocyte differentiation and function. A Review in the Theme: Cellular Responses to Hypoxia.

Tao JH, Barbi J, Pan F.

Am J Physiol Cell Physiol. 2015 Nov 1;309(9):C580-9. doi: 10.1152/ajpcell.00204.2015. Epub 2015 Sep 9. Review.


Omenn syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency.

Fuchs S, Rensing-Ehl A, Pannicke U, Lorenz MR, Fisch P, Jeelall Y, Rohr J, Speckmann C, Vraetz T, Farmand S, Schmitt-Graeff A, Krüger M, Strahm B, Henneke P, Enders A, Horikawa K, Goodnow C, Schwarz K, Ehl S.

Blood. 2015 Oct 1;126(14):1658-69. doi: 10.1182/blood-2015-03-631374. Epub 2015 Aug 19.


TCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complex.

Shi JH, Sun SC.

Mol Immunol. 2015 Dec;68(2 Pt C):546-57. doi: 10.1016/j.molimm.2015.07.024. Epub 2015 Aug 8. Review.


IL-6 and ICOS Antagonize Bim and Promote Regulatory T Cell Accrual with Age.

Raynor J, Karns R, Almanan M, Li KP, Divanovic S, Chougnet CA, Hildeman DA.

J Immunol. 2015 Aug 1;195(3):944-52. doi: 10.4049/jimmunol.1500443. Epub 2015 Jun 24.


Central role of gimap5 in maintaining peripheral tolerance and T cell homeostasis in the gut.

Endale M, Aksoylar HI, Hoebe K.

Mediators Inflamm. 2015;2015:436017. doi: 10.1155/2015/436017. Epub 2015 Apr 7. Review.


Slp-76 is a critical determinant of NK-cell mediated recognition of missing-self targets.

Lampe K, Endale M, Cashman S, Fang H, Mattner J, Hildeman D, Hoebe K.

Eur J Immunol. 2015 Jul;45(7):2072-83. doi: 10.1002/eji.201445352. Epub 2015 May 22.


Survival and maintenance of regulatory T cells require the kinase TAK1.

Chang JH, Hu H, Sun SC.

Cell Mol Immunol. 2015 Sep;12(5):572-9. doi: 10.1038/cmi.2015.27. Epub 2015 Apr 20.


T cell-NF-κB activation is required for tumor control in vivo.

Barnes SE, Wang Y, Chen L, Molinero LL, Gajewski TF, Evaristo C, Alegre ML.

J Immunother Cancer. 2015 Jan 20;3(1):1. doi: 10.1186/s40425-014-0045-x. eCollection 2015.


Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity.

Jaworski M, Marsland BJ, Gehrig J, Held W, Favre S, Luther SA, Perroud M, Golshayan D, Gaide O, Thome M.

EMBO J. 2014 Dec 1;33(23):2765-81. doi: 10.15252/embj.201488987. Epub 2014 Oct 15.


Ubiquitous points of control over regulatory T cells.

Pan F, Barbi J.

J Mol Med (Berl). 2014 Jun;92(6):555-69. doi: 10.1007/s00109-014-1156-z. Epub 2014 Apr 29. Review.


The Treg-specific demethylated region stabilizes Foxp3 expression independently of NF-κB signaling.

Schreiber L, Pietzsch B, Floess S, Farah C, Jänsch L, Schmitz I, Huehn J.

PLoS One. 2014 Feb 5;9(2):e88318. doi: 10.1371/journal.pone.0088318. eCollection 2014.


Thymic versus induced regulatory T cells - who regulates the regulators?

Povoleri GA, Scottà C, Nova-Lamperti EA, John S, Lombardi G, Afzali B.

Front Immunol. 2013 Jun 27;4:169. doi: 10.3389/fimmu.2013.00169. Print 2013.


The role of CARMA1 in T cells.

Roche MI, Ramadas RA, Medoff BD.

Crit Rev Immunol. 2013;33(3):219-43. Review.


T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells.

Qiao G, Zhao Y, Li Z, Tang PQ, Langdon WY, Yang T, Zhang J.

J Immunol. 2013 Jul 15;191(2):632-9. doi: 10.4049/jimmunol.1202068. Epub 2013 Jun 7.

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