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Items: 17

1.

Simple Derivation of Spinal Motor Neurons from ESCs/iPSCs Using Sendai Virus Vectors.

Goto K, Imamura K, Komatsu K, Mitani K, Aiba K, Nakatsuji N, Inoue M, Kawata A, Yamashita H, Takahashi R, Inoue H.

Mol Ther Methods Clin Dev. 2017 Jan 10;4:115-125. doi: 10.1016/j.omtm.2016.12.007. eCollection 2017 Mar 17.

2.

Motor neurons derived from ALS-related mouse iPS cells recapitulate pathological features of ALS.

Park JH, Park HS, Hong S, Kang S.

Exp Mol Med. 2016 Dec 9;48(12):e276. doi: 10.1038/emm.2016.113.

3.

rAAV Gene Therapy in a Canavan's Disease Mouse Model Reveals Immune Impairments and an Extended Pathology Beyond the Central Nervous System.

Ahmed SS, Schattgen SA, Frakes AE, Sikoglu EM, Su Q, Li J, Hampton TG, Denninger AR, Kirschner DA, Kaspar B, Matalon R, Gao G.

Mol Ther. 2016 Jun;24(6):1030-1041. doi: 10.1038/mt.2016.68. Epub 2016 Apr 4.

4.

Reverse engineering human neurodegenerative disease using pluripotent stem cell technology.

Liu Y, Deng W.

Brain Res. 2016 May 1;1638(Pt A):30-41. doi: 10.1016/j.brainres.2015.09.023. Epub 2015 Sep 28. Review.

5.

Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells.

Sun Y, Yong KM, Villa-Diaz LG, Zhang X, Chen W, Philson R, Weng S, Xu H, Krebsbach PH, Fu J.

Nat Mater. 2014 Jun;13(6):599-604. doi: 10.1038/nmat3945. Epub 2014 Apr 13.

6.

Retrograde labeling, transduction, and genetic targeting allow cellular analysis of corticospinal motor neurons: implications in health and disease.

Jara JH, Genç B, Klessner JL, Ozdinler PH.

Front Neuroanat. 2014 Mar 26;8:16. doi: 10.3389/fnana.2014.00016. eCollection 2014. Review.

7.

Amyotrophic lateral sclerosis: applications of stem cells - an update.

Cova L, Silani V.

Stem Cells Cloning. 2010 Oct 27;3:145-56. doi: 10.2147/SCCAA.S8662. Review.

8.

Disease modeling and drug screening for neurological diseases using human induced pluripotent stem cells.

Xu XH, Zhong Z.

Acta Pharmacol Sin. 2013 Jun;34(6):755-64. doi: 10.1038/aps.2013.63. Epub 2013 May 20. Review.

9.

Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling.

Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel CS, Höing S, Moritz S, Parga JA, Wagner L, Bruder JM, Wu G, Schmid B, Röpke A, Klingauf J, Schwamborn JC, Gasser T, Schöler HR, Sterneckert J.

PLoS One. 2013;8(3):e59252. doi: 10.1371/journal.pone.0059252. Epub 2013 Mar 22. Erratum in: PLoS One. 2013;8(11). doi:10.1371/annotation/6a917a2e-df4a-4ad9-99bb-6aa7218b833e.

10.

Recapitulation of spinal motor neuron-specific disease phenotypes in a human cell model of spinal muscular atrophy.

Wang ZB, Zhang X, Li XJ.

Cell Res. 2013 Mar;23(3):378-93. doi: 10.1038/cr.2012.166. Epub 2012 Dec 4.

11.

Amyotrophic lateral sclerosis model derived from human embryonic stem cells overexpressing mutant superoxide dismutase 1.

Wada T, Goparaju SK, Tooi N, Inoue H, Takahashi R, Nakatsuji N, Aiba K.

Stem Cells Transl Med. 2012 May;1(5):396-402. doi: 10.5966/sctm.2011-0061. Epub 2012 May 8.

12.

Functional neuromuscular junctions formed by embryonic stem cell-derived motor neurons.

Umbach JA, Adams KL, Gundersen CB, Novitch BG.

PLoS One. 2012;7(5):e36049. doi: 10.1371/journal.pone.0036049. Epub 2012 May 4.

13.

Superoxide dismutase 1 encoding mutations linked to ALS adopts a spectrum of misfolded states.

Prudencio M, Borchelt DR.

Mol Neurodegener. 2011 Nov 17;6:77. doi: 10.1186/1750-1326-6-77.

14.

Neuromuscular junction formation between human stem cell-derived motoneurons and human skeletal muscle in a defined system.

Guo X, Gonzalez M, Stancescu M, Vandenburgh HH, Hickman JJ.

Biomaterials. 2011 Dec;32(36):9602-11. doi: 10.1016/j.biomaterials.2011.09.014. Epub 2011 Sep 23.

15.

Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases.

Marchetto MC, Winner B, Gage FH.

Hum Mol Genet. 2010 Apr 15;19(R1):R71-6. doi: 10.1093/hmg/ddq159. Epub 2010 Apr 23. Review.

16.

Developmental regulation of human embryonic stem cell-derived neurons by calcium entry via transient receptor potential channels.

Weick JP, Austin Johnson M, Zhang SC.

Stem Cells. 2009 Dec;27(12):2906-16. doi: 10.1002/stem.212.

17.

Highly efficient differentiation and enrichment of spinal motor neurons derived from human and monkey embryonic stem cells.

Wada T, Honda M, Minami I, Tooi N, Amagai Y, Nakatsuji N, Aiba K.

PLoS One. 2009 Aug 24;4(8):e6722. doi: 10.1371/journal.pone.0006722.

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