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ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.

Jaiswal H, Benada J, Müllers E, Akopyan K, Burdova K, Koolmeister T, Helleday T, Medema RH, Macurek L, Lindqvist A.

EMBO J. 2017 Jul 14;36(14):2161-2176. doi: 10.15252/embj.201696082. Epub 2017 Jun 12.


Radiation-inducible miR-770-5p sensitizes tumors to radiation through direct targeting of PDZ-binding kinase.

Lee HC, Her NG, Kang D, Jung SH, Shin J, Lee M, Bae IH, Kim YN, Park HJ, Ko YG, Lee JS.

Cell Death Dis. 2017 Mar 23;8(3):e2693. doi: 10.1038/cddis.2017.116.


TET3-mediated DNA oxidation promotes ATR-dependent DNA damage response.

Jiang D, Wei S, Chen F, Zhang Y, Li J.

EMBO Rep. 2017 May;18(5):781-796. doi: 10.15252/embr.201643179. Epub 2017 Mar 21.


Combined Effect of Silica Nanoparticles and Benzo[a]pyrene on Cell Cycle Arrest Induction and Apoptosis in Human Umbilical Vein Endothelial Cells.

Asweto CO, Wu J, Hu H, Feng L, Yang X, Duan J, Sun Z.

Int J Environ Res Public Health. 2017 Mar 9;14(3). pii: E289. doi: 10.3390/ijerph14030289.


Evolution of protein-protein interaction networks in yeast.

Schoenrock A, Burnside D, Moteshareie H, Pitre S, Hooshyar M, Green JR, Golshani A, Dehne F, Wong A.

PLoS One. 2017 Mar 1;12(3):e0171920. doi: 10.1371/journal.pone.0171920. eCollection 2017.


Modulation of the DNA damage response during the life cycle of human papillomaviruses.

Anacker DC, Moody CA.

Virus Res. 2017 Mar 2;231:41-49. doi: 10.1016/j.virusres.2016.11.006. Epub 2016 Nov 9. Review.


Proteomics insights into DNA damage response and translating this knowledge to clinical strategies.

von Stechow L, Olsen JV.

Proteomics. 2017 Feb;17(3-4). doi: 10.1002/pmic.201600018. Epub 2016 Dec 12. Review.


Molecular signaling cascades involved in nonmelanoma skin carcinogenesis.

Feehan RP, Shantz LM.

Biochem J. 2016 Oct 1;473(19):2973-94. doi: 10.1042/BCJ20160471. Review.


DNA Repair and Cytokines: TGF-β, IL-6, and Thrombopoietin as Different Biomarkers of Radioresistance.

Centurione L, Aiello FB.

Front Oncol. 2016 Jul 22;6:175. doi: 10.3389/fonc.2016.00175. eCollection 2016. Review.


Increasing sensitivity to DNA damage is a potential driver for human ovarian cancer.

Jin Y, Xu X, Wang X, Kuang H, Osterman M, Feng S, Han D, Wu Y, Li M, Guo H.

Oncotarget. 2016 Aug 2;7(31):49710-49721. doi: 10.18632/oncotarget.10436.


Relationships between cell cycle pathway gene polymorphisms and risk of hepatocellular carcinoma.

Nan YL, Hu YL, Liu ZK, Duan FF, Xu Y, Li S, Li T, Chen DF, Zeng XY.

World J Gastroenterol. 2016 Jun 28;22(24):5558-67. doi: 10.3748/wjg.v22.i24.5558.


Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation.

Braun CJ, Bruno PM, Horlbeck MA, Gilbert LA, Weissman JS, Hemann MT.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):E3892-900. doi: 10.1073/pnas.1600582113. Epub 2016 Jun 20.


Identification of S-phase DNA damage-response targets in fission yeast reveals conservation of damage-response networks.

Willis NA, Zhou C, Elia AE, Murray JM, Carr AM, Elledge SJ, Rhind N.

Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3676-85. doi: 10.1073/pnas.1525620113. Epub 2016 Jun 13.


Dual inhibition of ATR and ATM potentiates the activity of trabectedin and lurbinectedin by perturbing the DNA damage response and homologous recombination repair.

Lima M, Bouzid H, Soares DG, Selle F, Morel C, Galmarini CM, Henriques JA, Larsen AK, Escargueil AE.

Oncotarget. 2016 May 3;7(18):25885-901. doi: 10.18632/oncotarget.8292.


Aspartate Rescues S-phase Arrest Caused by Suppression of Glutamine Utilization in KRas-driven Cancer Cells.

Patel D, Menon D, Bernfeld E, Mroz V, Kalan S, Loayza D, Foster DA.

J Biol Chem. 2016 Apr 22;291(17):9322-9. doi: 10.1074/jbc.M115.710145. Epub 2016 Feb 26.


TopBP1-mediated DNA processing during mitosis.

Gallina I, Christiansen SK, Pedersen RT, Lisby M, Oestergaard VH.

Cell Cycle. 2016;15(2):176-83. doi: 10.1080/15384101.2015.1128595.


DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E2 Growth Factor Release in Response to Low and High LET Ionizing Radiation.

Allen CP, Tinganelli W, Sharma N, Nie J, Sicard C, Natale F, King M 3rd, Keysar SB, Jimeno A, Furusawa Y, Okayasu R, Fujimori A, Durante M, Nickoloff JA.

Front Oncol. 2015 Dec 7;5:260. doi: 10.3389/fonc.2015.00260. eCollection 2015.


PrimPol-deficient cells exhibit a pronounced G2 checkpoint response following UV damage.

Bailey LJ, Bianchi J, Hégarat N, Hochegger H, Doherty AJ.

Cell Cycle. 2016;15(7):908-18. doi: 10.1080/15384101.2015.1128597. Epub 2015 Dec 22.


Checkpoint kinase 1 inhibitors as targeted molecular agents for clear cell carcinoma of the ovary.

Kobayashi H, Shigetomi H, Yoshimoto C.

Oncol Lett. 2015 Aug;10(2):571-576. Epub 2015 May 26.

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