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Mislocalisation of BEST1 in iPSC-derived retinal pigment epithelial cells from a family with autosomal dominant vitreoretinochoroidopathy (ADVIRC).

Carter DA, Smart MJ, Letton WV, Ramsden CM, Nommiste B, Chen LL, Fynes K, Muthiah MN, Goh P, Lane A, Powner MB, Webster AR, da Cruz L, Moore AT, Coffey PJ, Carr AF.

Sci Rep. 2016 Sep 22;6:33792. doi: 10.1038/srep33792.


Targeting the cAMP and Transforming Growth Factor-β Pathway Increases Proliferation to Promote Re-Epithelialization of Human Stem Cell-Derived Retinal Pigment Epithelium.

Choudhary P, Gutteridge A, Impey E, Storer RI, Owen RM, Whiting PJ, Bictash M, Benn CL.

Stem Cells Transl Med. 2016 Jul;5(7):925-37. doi: 10.5966/sctm.2015-0247.


Features specific to retinal pigment epithelium cells derived from three-dimensional human embryonic stem cell cultures - a new donor for cell therapy.

Wu W, Zeng Y, Li Z, Li Q, Xu H, Yin ZQ.

Oncotarget. 2016 Apr 19;7(16):22819-33. doi: 10.18632/oncotarget.8185.


Robust Differentiation of mRNA-Reprogrammed Human Induced Pluripotent Stem Cells Toward a Retinal Lineage.

Sridhar A, Ohlemacher SK, Langer KB, Meyer JS.

Stem Cells Transl Med. 2016 Apr;5(4):417-26. doi: 10.5966/sctm.2015-0093.


iPSC-Derived Retinal Pigment Epithelium Allografts Do Not Elicit Detrimental Effects in Rats: A Follow-Up Study.

Westenskow PD, Bucher F, Bravo S, Kurihara T, Feitelberg D, Paris LP, Aguilar E, Lin JH, Friedlander M.

Stem Cells Int. 2016;2016:8470263. doi: 10.1155/2016/8470263.


Looking into the future: Using induced pluripotent stem cells to build two and three dimensional ocular tissue for cell therapy and disease modeling.

Song MJ, Bharti K.

Brain Res. 2016 May 1;1638(Pt A):2-14. doi: 10.1016/j.brainres.2015.12.011. Review.


Current therapeutic developments in atrophic age-related macular degeneration.

Hanus J, Zhao F, Wang S.

Br J Ophthalmol. 2016 Jan;100(1):122-7. doi: 10.1136/bjophthalmol-2015-306972. Review. Erratum in: Br J Ophthalmol. 2016 Jun;100(6):744.


Human Adult Retinal Pigment Epithelial Stem Cell-Derived RPE Monolayers Exhibit Key Physiological Characteristics of Native Tissue.

Blenkinsop TA, Saini JS, Maminishkis A, Bharti K, Wan Q, Banzon T, Lotfi M, Davis J, Singh D, Rizzolo LJ, Miller S, Temple S, Stern JH.

Invest Ophthalmol Vis Sci. 2015 Nov;56(12):7085-99. doi: 10.1167/iovs.14-16246.


Progressing a human embryonic stem-cell-based regenerative medicine therapy towards the clinic.

Whiting P, Kerby J, Coffey P, da Cruz L, McKernan R.

Philos Trans R Soc Lond B Biol Sci. 2015 Oct 19;370(1680):20140375. doi: 10.1098/rstb.2014.0375. Review.


Human iPSC derived disease model of MERTK-associated retinitis pigmentosa.

Lukovic D, Artero Castro A, Delgado AB, Bernal Mde L, Luna Pelaez N, Díez Lloret A, Perez Espejo R, Kamenarova K, Fernández Sánchez L, Cuenca N, Cortón M, Avila Fernandez A, Sorkio A, Skottman H, Ayuso C, Erceg S, Bhattacharya SS.

Sci Rep. 2015 Aug 11;5:12910. doi: 10.1038/srep12910.


Use of human pluripotent stem cells to study and treat retinopathies.

Ben M'Barek K, Regent F, Monville C.

World J Stem Cells. 2015 Apr 26;7(3):596-604. doi: 10.4252/wjsc.v7.i3.596. Review.


Efficient derivation of retinal pigment epithelium cells from stem cells.

Westenskow P, Sedillo Z, Barnett A, Friedlander M.

J Vis Exp. 2015 Mar 8;(97). doi: 10.3791/52214.


Stem cell treatment of degenerative eye disease.

Mead B, Berry M, Logan A, Scott RA, Leadbeater W, Scheven BA.

Stem Cell Res. 2015 May;14(3):243-57. doi: 10.1016/j.scr.2015.02.003. Review.


Enhanced functional integration of human photoreceptor precursors into human and rodent retina in an ex vivo retinal explant model system.

Yanai A, Laver CR, Gregory-Evans CY, Liu RR, Gregory-Evans K.

Tissue Eng Part A. 2015 Jun;21(11-12):1763-71. doi: 10.1089/ten.TEA.2014.0669.


Performing subretinal injections in rodents to deliver retinal pigment epithelium cells in suspension.

Westenskow PD, Kurihara T, Bravo S, Feitelberg D, Sedillo ZA, Aguilar E, Friedlander M.

J Vis Exp. 2015 Jan 23;(95):52247. doi: 10.3791/52247.


Large-scale purification of porcine or bovine photoreceptor outer segments for phagocytosis assays on retinal pigment epithelial cells.

Parinot C, Rieu Q, Chatagnon J, Finnemann SC, Nandrot EF.

J Vis Exp. 2014 Dec 12;(94). doi: 10.3791/52100.


Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells.

Schwarz N, Carr AJ, Lane A, Moeller F, Chen LL, Aguilà M, Nommiste B, Muthiah MN, Kanuga N, Wolfrum U, Nagel-Wolfrum K, da Cruz L, Coffey PJ, Cheetham ME, Hardcastle AJ.

Hum Mol Genet. 2015 Feb 15;24(4):972-86. doi: 10.1093/hmg/ddu509.


Engineering efficient retinal pigment epithelium differentiation from human pluripotent stem cells.

Lane A, Philip LR, Ruban L, Fynes K, Smart M, Carr A, Mason C, Coffey P.

Stem Cells Transl Med. 2014 Nov;3(11):1295-304. doi: 10.5966/sctm.2014-0094.


Enhancing RPE Cell-Based Therapy Outcomes for AMD: The Role of Bruch's Membrane.

Heller JP, Martin KR.

Transl Vis Sci Technol. 2014 Jul 3;3(3):11.


Understanding photoreceptor outer segment phagocytosis: use and utility of RPE cells in culture.

Mazzoni F, Safa H, Finnemann SC.

Exp Eye Res. 2014 Sep;126:51-60. doi: 10.1016/j.exer.2014.01.010. Review.

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