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The curious case of vacuolar ATPase: regulation of signaling pathways.

Pamarthy S, Kulshrestha A, Katara GK, Beaman KD.

Mol Cancer. 2018 Feb 15;17(1):41. doi: 10.1186/s12943-018-0811-3. Review.


Rethinking the Combination of Proton Exchanger Inhibitors in Cancer Therapy.

Iessi E, Logozzi M, Mizzoni D, Di Raimo R, Supuran CT, Fais S.

Metabolites. 2017 Dec 23;8(1). pii: E2. doi: 10.3390/metabo8010002. Review.


The pH stability of foot-and-mouth disease virus.

Yuan H, Li P, Ma X, Lu Z, Sun P, Bai X, Zhang J, Bao H, Cao Y, Li D, Fu Y, Chen Y, Bai Q, Zhang J, Liu Z.

Virol J. 2017 Nov 28;14(1):233. doi: 10.1186/s12985-017-0897-z. Review.


Reiterative epoxide-based strategies for the synthesis of stereo-n-ads and application to polypropionate synthesis. A Personal Account.

Cruz-Montañez A, Morales-Rivera KF, Torres W, Valentín EM, Rentas J, Prieto JA.

Inorganica Chim Acta. 2017 Nov 1;468:28-37. doi: 10.1016/j.ica.2017.06.042. Epub 2017 Jun 15.


F-actin reorganization by V-ATPase inhibition in prostate cancer.

Licon-Munoz Y, Michel V, Fordyce CA, Parra KJ.

Biol Open. 2017 Nov 15;6(11):1734-1744. doi: 10.1242/bio.028837.


Nanoparticulate vacuolar ATPase blocker exhibits potent host-targeted antiviral activity against feline coronavirus.

Hu CJ, Chang WS, Fang ZS, Chen YT, Wang WL, Tsai HH, Chueh LL, Takano T, Hohdatsu T, Chen HW.

Sci Rep. 2017 Oct 12;7(1):13043. doi: 10.1038/s41598-017-13316-0.


Direct interaction of the Golgi V-ATPase a-subunit isoform with PI(4)P drives localization of Golgi V-ATPases in yeast.

Banerjee S, Kane PM.

Mol Biol Cell. 2017 Sep 15;28(19):2518-2530. doi: 10.1091/mbc.E17-05-0316. Epub 2017 Jul 18.


The interaction of the bioinsecticide PA1b (Pea Albumin 1 subunit b) with the insect V-ATPase triggers apoptosis.

Eyraud V, Balmand S, Karaki L, Rahioui I, Sivignon C, Delmas AF, Royer C, Rahbé Y, Da Silva P, Gressent F.

Sci Rep. 2017 Jul 7;7(1):4902. doi: 10.1038/s41598-017-05315-y.


Functional inhibition of acid sphingomyelinase by Fluphenazine triggers hypoxia-specific tumor cell death.

Klutzny S, Lesche R, Keck M, Kaulfuss S, Schlicker A, Christian S, Sperl C, Neuhaus R, Mowat J, Steckel M, Riefke B, Prechtl S, Parczyk K, Steigemann P.

Cell Death Dis. 2017 Mar 30;8(3):e2709. doi: 10.1038/cddis.2017.130.


Covalent Modulators of the Vacuolar ATPase.

Chen YC, Backus KM, Merkulova M, Yang C, Brown D, Cravatt BF, Zhang C.

J Am Chem Soc. 2017 Jan 18;139(2):639-642. doi: 10.1021/jacs.6b12511. Epub 2016 Dec 30.


Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+-ATPase.

Pereira CS, Guedes JP, Gonçalves M, Loureiro L, Castro L, Gerós H, Rodrigues LR, Côrte-Real M.

Oncotarget. 2016 Sep 20;7(38):62144-62158. doi: 10.18632/oncotarget.11394.


Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium.

Pelkonen L, Reinisalo M, Morin-Picardat E, Kidron H, Urtti A.

PLoS One. 2016 Aug 23;11(8):e0160352. doi: 10.1371/journal.pone.0160352. eCollection 2016.


Local anesthetics induce autophagy in young permanent tooth pulp cells.

Zhuang H, Hu D, Singer D, Walker JV, Nisr RB, Tieu K, Ali K, Tredwin C, Luo S, Ardu S, Hu B.

Cell Death Discov. 2015 Sep 7;1:15024. doi: 10.1038/cddiscovery.2015.24. eCollection 2015.


Anti-leukemic effects of the V-ATPase inhibitor Archazolid A.

Zhang S, Schneider LS, Vick B, Grunert M, Jeremias I, Menche D, Müller R, Vollmar AM, Liebl J.

Oncotarget. 2015 Dec 22;6(41):43508-28. doi: 10.18632/oncotarget.6180.


NR1D1 ameliorates Mycobacterium tuberculosis clearance through regulation of autophagy.

Chandra V, Bhagyaraj E, Nanduri R, Ahuja N, Gupta P.

Autophagy. 2015 Nov 2;11(11):1987-1997.


DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation.

Faronato M, Nguyen VT, Patten DK, Lombardo Y, Steel JH, Patel N, Woodley L, Shousha S, Pruneri G, Coombes RC, Magnani L.

Oncotarget. 2015 Sep 8;6(26):22467-79.


A novel lung explant model for the ex vivo study of efficacy and mechanisms of anti-influenza drugs.

Nicholas B, Staples KJ, Moese S, Meldrum E, Ward J, Dennison P, Havelock T, Hinks TS, Amer K, Woo E, Chamberlain M, Singh N, North M, Pink S, Wilkinson TM, Djukanović R.

J Immunol. 2015 Jun 15;194(12):6144-54. doi: 10.4049/jimmunol.1402283. Epub 2015 May 1.


Discovery of a Small-Molecule Probe for V-ATPase Function.

Aldrich LN, Kuo SY, Castoreno AB, Goel G, Kuballa P, Rees MG, Seashore-Ludlow BA, Cheah JH, Latorre IJ, Schreiber SL, Shamji AF, Xavier RJ.

J Am Chem Soc. 2015 Apr 29;137(16):5563-8. doi: 10.1021/jacs.5b02150. Epub 2015 Apr 20.


Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A.

Lu Y, Dong S, Hao B, Li C, Zhu K, Guo W, Wang Q, Cheung KH, Wong CW, Wu WT, Markus H, Yue J.

Autophagy. 2014;10(11):1895-905. doi: 10.4161/auto.32200. Epub 2014 Oct 30. Erratum in: Autophagy. 2018;14 (1):176-177.


Mutations in the proteolipid subunits of the vacuolar H+-ATPase provide resistance to indolotryptoline natural products.

Chang FY, Kawashima SA, Brady SF.

Biochemistry. 2014 Nov 18;53(45):7123-31. doi: 10.1021/bi501078j. Epub 2014 Oct 31.

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