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Items: 1 to 20 of 22


Splice Variants of the RTK Family: Their Role in Tumour Progression and Response to Targeted Therapy.

Abou-Fayçal C, Hatat AS, Gazzeri S, Eymin B.

Int J Mol Sci. 2017 Feb 11;18(2). pii: E383. doi: 10.3390/ijms18020383. Review.


Ectodomain cleavage of FLT1 regulates receptor activation and function and is not required for its downstream intracellular cleavage.

Raikwar NS, Liu KZ, Thomas CP.

Exp Cell Res. 2016 May 15;344(1):103-11. doi: 10.1016/j.yexcr.2016.03.020. Epub 2016 Mar 23.


Circulating Levels of sFlt1 Splice Variants as Predictive Markers for the Development of Preeclampsia.

Souders CA, Maynard SE, Yan J, Wang Y, Boatright NK, Sedan J, Balyozian D, Cheslock PS, Molrine DC, Simas TA.

Int J Mol Sci. 2015 Jun 2;16(6):12436-53. doi: 10.3390/ijms160612436.


Full-length human placental sFlt-1-e15a isoform induces distinct maternal phenotypes of preeclampsia in mice.

Szalai G, Romero R, Chaiworapongsa T, Xu Y, Wang B, Ahn H, Xu Z, Chiang PJ, Sundell B, Wang R, Jiang Y, Plazyo O, Olive M, Tarca AL, Dong Z, Qureshi F, Papp Z, Hassan SS, Hernandez-Andrade E, Than NG.

PLoS One. 2015 Apr 10;10(4):e0119547. doi: 10.1371/journal.pone.0119547. eCollection 2015.


Regulation of soluble fms-like tyrosine kinase-1 production in response to placental ischemia/hypoxia: role of angiotensin II.

Murphy SR, Cockrell K.

Physiol Rep. 2015 Feb 25;3(2). pii: e12310. doi: 10.14814/phy2.12310. Print 2015 Feb 1.


Oxidative stress in preeclampsia and the role of free fetal hemoglobin.

Hansson SR, Nääv Å, Erlandsson L.

Front Physiol. 2015 Jan 13;5:516. doi: 10.3389/fphys.2014.00516. eCollection 2014. Review.


In vivo experiments reveal the good, the bad and the ugly faces of sFlt-1 in pregnancy.

Szalai G, Xu Y, Romero R, Chaiworapongsa T, Xu Z, Chiang PJ, Ahn H, Sundell B, Plazyo O, Jiang Y, Olive M, Wang B, Jacques SM, Qureshi F, Tarca AL, Erez O, Dong Z, Papp Z, Hassan SS, Hernandez-Andrade E, Than NG.

PLoS One. 2014 Nov 13;9(11):e110867. doi: 10.1371/journal.pone.0110867. eCollection 2014.


Attenuation of VEGFR-2 expression by sFlt-1 and low oxygen in human placenta.

Nevo O, Lee DK, Caniggia I.

PLoS One. 2013 Nov 19;8(11):e81176. doi: 10.1371/journal.pone.0081176. eCollection 2013.


Differential placental methylation and expression of VEGF, FLT-1 and KDR genes in human term and preterm preeclampsia.

Sundrani DP, Reddy US, Joshi AA, Mehendale SS, Chavan-Gautam PM, Hardikar AA, Chandak GR, Joshi SR.

Clin Epigenetics. 2013 Apr 26;5(1):6. doi: 10.1186/1868-7083-5-6.


A comprehensive review of hypertension in pregnancy.

Mustafa R, Ahmed S, Gupta A, Venuto RC.

J Pregnancy. 2012;2012:105918. doi: 10.1155/2012/105918. Epub 2012 May 23. Review.


Low proliferative potential and impaired angiogenesis of cultured rat kidney endothelial cells.

Basile DP, Zeng P, Friedrich JL, Leonard EC, Yoder MC.

Microcirculation. 2012 Oct;19(7):598-609. doi: 10.1111/j.1549-8719.2012.00193.x.


Transcriptome landscape of the human placenta.

Kim J, Zhao K, Jiang P, Lu ZX, Wang J, Murray JC, Xing Y.

BMC Genomics. 2012 Mar 27;13:115. doi: 10.1186/1471-2164-13-115.


Elevated soluble Flt1 inhibits endothelial repair in PR3-ANCA-associated vasculitis.

Le Roux S, Pepper RJ, Dufay A, Néel M, Meffray E, Lamandé N, Rimbert M, Josien R, Hamidou M, Hourmant M, Cook HT, Charreau B, Larger E, Salama AD, Fakhouri F.

J Am Soc Nephrol. 2012 Jan;23(1):155-64. doi: 10.1681/ASN.2010080858. Epub 2011 Oct 27.


Preeclampsia, a disease of the maternal endothelium: the role of antiangiogenic factors and implications for later cardiovascular disease.

Powe CE, Levine RJ, Karumanchi SA.

Circulation. 2011 Jun 21;123(24):2856-69. doi: 10.1161/CIRCULATIONAHA.109.853127. Review. No abstract available.


Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1.

Boeckel JN, Guarani V, Koyanagi M, Roexe T, Lengeling A, Schermuly RT, Gellert P, Braun T, Zeiher A, Dimmeler S.

Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3276-81. doi: 10.1073/pnas.1008098108. Epub 2011 Feb 7.


Angiogenic factors and preeclampsia.

Maynard SE, Karumanchi SA.

Semin Nephrol. 2011 Jan;31(1):33-46. doi: 10.1016/j.semnephrol.2010.10.004. Review.


Soluble FLT1 sensitizes endothelial cells to inflammatory cytokines by antagonizing VEGF receptor-mediated signalling.

Cindrova-Davies T, Sanders DA, Burton GJ, Charnock-Jones DS.

Cardiovasc Res. 2011 Feb 15;89(3):671-9. doi: 10.1093/cvr/cvq346. Epub 2010 Dec 7.


Adenoviral delivery of VEGF121 early in pregnancy prevents spontaneous development of preeclampsia in BPH/5 mice.

Woods AK, Hoffmann DS, Weydert CJ, Butler SD, Zhou Y, Sharma RV, Davisson RL.

Hypertension. 2011 Jan;57(1):94-102. doi: 10.1161/HYPERTENSIONAHA.110.160242. Epub 2010 Nov 15.


Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes.

Eubank TD, Roda JM, Liu H, O'Neil T, Marsh CB.

Blood. 2011 Jan 6;117(1):323-32. doi: 10.1182/blood-2010-01-261792. Epub 2010 Oct 15.


Alternate processing of Flt1 transcripts is directed by conserved cis-elements within an intronic region of FLT1 that reciprocally regulates splicing and polyadenylation.

Thomas CP, Raikwar NS, Kelley EA, Liu KZ.

Nucleic Acids Res. 2010 Aug;38(15):5130-40. doi: 10.1093/nar/gkq198. Epub 2010 Apr 12.

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