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Items: 8


Clinical Trial of 2-Phenethyl Isothiocyanate as an Inhibitor of Metabolic Activation of a Tobacco-Specific Lung Carcinogen in Cigarette Smokers.

Yuan JM, Stepanov I, Murphy SE, Wang R, Allen S, Jensen J, Strayer L, Adams-Haduch J, Upadhyaya P, Le C, Kurzer MS, Nelson HH, Yu MC, Hatsukami D, Hecht SS.

Cancer Prev Res (Phila). 2016 May;9(5):396-405. doi: 10.1158/1940-6207.CAPR-15-0380. Epub 2016 Mar 7.


Phenethyl isothiocyanate: a comprehensive review of anti-cancer mechanisms.

Gupta P, Wright SE, Kim SH, Srivastava SK.

Biochim Biophys Acta. 2014 Dec;1846(2):405-24. doi: 10.1016/j.bbcan.2014.08.003. Epub 2014 Aug 23. Review.


Chemoprevention of lung cancer: prospects and disappointments in human clinical trials.

Greenberg AK, Tsay JC, Tchou-Wong KM, Jorgensen A, Rom WN.

Cancers (Basel). 2013 Jan 24;5(1):131-48. doi: 10.3390/cancers5010131.


Enhanced inhibition of lung adenocarcinoma by combinatorial treatment with indole-3-carbinol and silibinin in A/J mice.

Dagne A, Melkamu T, Schutten MM, Qian X, Upadhyaya P, Luo X, Kassie F.

Carcinogenesis. 2011 Apr;32(4):561-7. doi: 10.1093/carcin/bgr010. Epub 2011 Jan 27.


Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination.

Kassie F, Melkamu T, Endalew A, Upadhyaya P, Luo X, Hecht SS.

Carcinogenesis. 2010 Sep;31(9):1634-41. doi: 10.1093/carcin/bgq139. Epub 2010 Jul 5.


The role of the Akt/mTOR pathway in tobacco carcinogen-induced lung tumorigenesis.

Memmott RM, Dennis PA.

Clin Cancer Res. 2010 Jan 1;16(1):4-10. doi: 10.1158/1078-0432.CCR-09-0234. Epub 2009 Dec 22.


Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice.

Kassie F, Kalscheuer S, Matise I, Ma L, Melkamu T, Upadhyaya P, Hecht SS.

Carcinogenesis. 2010 Feb;31(2):239-45. doi: 10.1093/carcin/bgp174. Epub 2009 Jul 22.


Chemoprevention of lung carcinogenesis in addicted smokers and ex-smokers.

Hecht SS, Kassie F, Hatsukami DK.

Nat Rev Cancer. 2009 Jul;9(7):476-88. doi: 10.1038/nrc2674. Review.

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