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Items: 1 to 20 of 36


Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation.

Meng F, Zhou R, Wu S, Zhang Q, Jin Q, Zhou Y, Plouffe SW, Liu S, Song H, Xia Z, Zhao B, Ye S, Feng XH, Guan KL, Zou J, Xu P.

Genes Dev. 2016 May 1;30(9):1086-100. doi: 10.1101/gad.277533.116.


Defective Leukocyte Adhesion and Chemotaxis Contributes to Combined Immunodeficiency in Humans with Autosomal Recessive MST1 Deficiency.

Dang TS, Willet JD, Griffin HR, Morgan NV, O'Boyle G, Arkwright PD, Hughes SM, Abinun M, Tee LJ, Barge D, Engelhardt KR, Jackson M, Cant AJ, Maher ER, Koref MS, Reynard LN, Ali S, Hambleton S.

J Clin Immunol. 2016 Feb;36(2):117-22. doi: 10.1007/s10875-016-0232-2. Erratum in: J Clin Immunol. 2016 Apr;36(3):336-7.


STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.

Li W, Xiao J, Zhou X, Xu M, Hu C, Xu X, Lu Y, Liu C, Xue S, Nie L, Zhang H, Li Z, Zhang Y, Ji F, Hui L, Tao W, Wei B, Wang H.

J Clin Invest. 2015 Nov 2;125(11):4239-54. doi: 10.1172/JCI81203.


Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity.

Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, Hong L, Xie C, Li X, Zhao H, Liu Q, Jiang M, Chen Q, Zhang J, Li Y, Song S, Wang HR, Zhou R, Johnson RL, Chien KY, Lin SC, Han J, Avruch J, Chen L, Zhou D.

Nat Immunol. 2015 Nov;16(11):1142-52. doi: 10.1038/ni.3268.


MST kinases in development and disease.

Thompson BJ, Sahai E.

J Cell Biol. 2015 Sep 14;210(6):871-82. doi: 10.1083/jcb.201507005. Review.


Regulation of mammalian Ste20 (Mst) kinases.

Rawat SJ, Chernoff J.

Trends Biochem Sci. 2015 Mar;40(3):149-56. doi: 10.1016/j.tibs.2015.01.001. Review.


Immunodeficiency and immune dysregulation associated with proximal defects of T cell receptor signaling.

Notarangelo LD.

Curr Opin Immunol. 2014 Dec;31:97-101. doi: 10.1016/j.coi.2014.10.003. Review.


Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration.

Xu X, Jaeger ER, Wang X, Lagler-Ferrez E, Batalov S, Mathis NL, Wiltshire T, Walker JR, Cooke MP, Sauer K, Huang YH.

PLoS One. 2014 Aug 18;9(8):e105561. doi: 10.1371/journal.pone.0105561.


The Hippo pathway in disease and therapy: cancer and beyond.

Gomez M, Gomez V, Hergovich A.

Clin Transl Med. 2014 Jul 10;3:22. doi: 10.1186/2001-1326-3-22. Review.


Genetic deletion of Mst1 alters T cell function and protects against autoimmunity.

Salojin KV, Hamman BD, Chang WC, Jhaver KG, Al-Shami A, Crisostomo J, Wilkins C, Digeorge-Foushee AM, Allen J, Patel N, Gopinathan S, Zhou J, Nouraldeen A, Jessop TC, Bagdanoff JT, Augeri DJ, Read R, Vogel P, Swaffield J, Wilson A, Platt KA, Carson KG, Main A, Zambrowicz BP, Oravecz T.

PLoS One. 2014 May 22;9(5):e98151. doi: 10.1371/journal.pone.0098151.


Functional role of Mst1/Mst2 in embryonic stem cell differentiation.

Li P, Chen Y, Mak KK, Wong CK, Wang CC, Yuan P.

PLoS One. 2013 Nov 5;8(11):e79867. doi: 10.1371/journal.pone.0079867.


Ras and rheb signaling in survival and cell death.

Ehrkamp A, Herrmann C, Stoll R, Heumann R.

Cancers (Basel). 2013 May 28;5(2):639-61. doi: 10.3390/cancers5020639.


Mst1 and Mst2 kinases: regulations and diseases.

Qin F, Tian J, Zhou D, Chen L.

Cell Biosci. 2013 Aug 28;3(1):31. doi: 10.1186/2045-3701-3-31.


What do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease.

Morgan JT, Murphy CJ, Russell P.

Exp Eye Res. 2013 Oct;115:1-12. doi: 10.1016/j.exer.2013.06.012. Review.


Partial defects of T-cell development associated with poor T-cell function.

Notarangelo LD.

J Allergy Clin Immunol. 2013 May;131(5):1297-305. doi: 10.1016/j.jaci.2013.01.020. Review.


Germinal center kinases in immune regulation.

Yin H, Shi Z, Jiao S, Chen C, Wang W, Greene MI, Zhou Z.

Cell Mol Immunol. 2012 Nov;9(6):439-45. doi: 10.1038/cmi.2012.30. Review.


Inherited MST1 deficiency underlies susceptibility to EV-HPV infections.

Crequer A, Picard C, Patin E, D'Amico A, Abhyankar A, Munzer M, Debré M, Zhang SY, de Saint-Basile G, Fischer A, Abel L, Orth G, Casanova JL, Jouanguy E.

PLoS One. 2012;7(8):e44010. doi: 10.1371/journal.pone.0044010.


Protein kinases of the Hippo pathway: regulation and substrates.

Avruch J, Zhou D, Fitamant J, Bardeesy N, Mou F, Barrufet LR.

Semin Cell Dev Biol. 2012 Sep;23(7):770-84. doi: 10.1016/j.semcdb.2012.07.002. Review.


Hippo pathway in intestinal homeostasis and tumorigenesis.

Chen L, Qin F, Deng X, Avruch J, Zhou D.

Protein Cell. 2012 Apr;3(4):305-10. doi: 10.1007/s13238-012-2913-9. Review.

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