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Effect of aging on stem cells.

Ahmed AS, Sheng MH, Wasnik S, Baylink DJ, Lau KW.

World J Exp Med. 2017 Feb 20;7(1):1-10. doi: 10.5493/wjem.v7.i1.1. eCollection 2017 Feb 20. Review.


AMPK regulates lipid accumulation in skeletal muscle cells through FTO-dependent demethylation of N6-methyladenosine.

Wu W, Feng J, Jiang D, Zhou X, Jiang Q, Cai M, Wang X, Shan T, Wang Y.

Sci Rep. 2017 Feb 8;7:41606. doi: 10.1038/srep41606.


Metabolomics and Metabolic Diseases: Where Do We Stand?

Newgard CB.

Cell Metab. 2017 Jan 10;25(1):43-56. doi: 10.1016/j.cmet.2016.09.018. Epub 2016 Oct 27. Review.


Thyroid hormone-stimulated increases in PGC-1α and UCP2 promote life history-specific endocrine changes and maintain a lipid-based metabolism.

Martinez B, Soñanez-Organis JG, Godoy-Lugo JA, Horin LJ, Crocker DE, Ortiz RM.

Am J Physiol Regul Integr Comp Physiol. 2017 Feb 1;312(2):R189-R196. doi: 10.1152/ajpregu.00395.2016. Epub 2016 Nov 30.


Oxidative Priority, Meal Frequency, and the Energy Economy of Food and Activity: Implications for Longevity, Obesity, and Cardiometabolic Disease.

Cronise RJ, Sinclair DA, Bremer AA.

Metab Syndr Relat Disord. 2017 Feb;15(1):6-17. doi: 10.1089/met.2016.0108. Epub 2016 Nov 21.


miR-34a(-/-) mice are susceptible to diet-induced obesity.

Lavery CA, Kurowska-Stolarska M, Holmes WM, Donnelly I, Caslake M, Collier A, Baker AH, Miller AM.

Obesity (Silver Spring). 2016 Aug;24(8):1741-51. doi: 10.1002/oby.21561. Epub 2016 Jul 5.


Hypophosphatemia promotes lower rates of muscle ATP synthesis.

Pesta DH, Tsirigotis DN, Befroy DE, Caballero D, Jurczak MJ, Rahimi Y, Cline GW, Dufour S, Birkenfeld AL, Rothman DL, Carpenter TO, Insogna K, Petersen KF, Bergwitz C, Shulman GI.

FASEB J. 2016 Oct;30(10):3378-3387. Epub 2016 Jun 23.


Exercise-like effects by Estrogen-related receptor-gamma in muscle do not prevent insulin resistance in db/db mice.

Badin PM, Vila IK, Sopariwala DH, Yadav V, Lorca S, Louche K, Kim ER, Tong Q, Song MS, Moro C, Narkar VA.

Sci Rep. 2016 May 25;6:26442. doi: 10.1038/srep26442.


A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.

Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z.

Nat Med. 2016 Apr;22(4):421-6. doi: 10.1038/nm.4057. Epub 2016 Mar 7.


Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial Function.

Zhang Y, Zhao Z, Ke B, Wan L, Wang H, Ye J.

PLoS One. 2016 Mar 1;11(3):e0150454. doi: 10.1371/journal.pone.0150454. eCollection 2016.


The role of oxidative stress in skeletal muscle injury and regeneration: focus on antioxidant enzymes.

Kozakowska M, Pietraszek-Gremplewicz K, Jozkowicz A, Dulak J.

J Muscle Res Cell Motil. 2015 Dec;36(6):377-93. doi: 10.1007/s10974-015-9438-9. Epub 2016 Jan 4. Review.


Evaluation of in vivo mitochondrial bioenergetics in skeletal muscle using NMR and optical methods.

Campbell MD, Marcinek DJ.

Biochim Biophys Acta. 2016 Apr;1862(4):716-24. doi: 10.1016/j.bbadis.2015.12.019. Epub 2015 Dec 17. Review.


Caloric restriction and exercise "mimetics'': Ready for prime time?

Handschin C.

Pharmacol Res. 2016 Jan;103:158-66. doi: 10.1016/j.phrs.2015.11.009. Epub 2015 Dec 2. Review.


Complex Coordination of Cell Plasticity by a PGC-1α-controlled Transcriptional Network in Skeletal Muscle.

Kupr B, Handschin C.

Front Physiol. 2015 Nov 9;6:325. doi: 10.3389/fphys.2015.00325. eCollection 2015. Review.


Supplementation of l-Alanyl-l-Glutamine and Fish Oil Improves Body Composition and Quality of Life in Patients With Chronic Heart Failure.

Wu C, Kato TS, Ji R, Zizola C, Brunjes DL, Deng Y, Akashi H, Armstrong HF, Kennel PJ, Thomas T, Forman DE, Hall J, Chokshi A, Bartels MN, Mancini D, Seres D, Schulze PC.

Circ Heart Fail. 2015 Nov;8(6):1077-87. doi: 10.1161/CIRCHEARTFAILURE.115.002073. Epub 2015 Aug 12.


IL-15Rα is a determinant of muscle fuel utilization, and its loss protects against obesity.

Loro E, Seifert EL, Moffat C, Romero F, Mishra MK, Sun Z, Krajacic P, Anokye-Danso F, Summer RS, Ahima RS, Khurana TS.

Am J Physiol Regul Integr Comp Physiol. 2015 Oct 15;309(8):R835-44. doi: 10.1152/ajpregu.00505.2014. Epub 2015 Aug 12.


Mitochondrial quality control, promoted by PGC-1α, is dysregulated by Western diet-induced obesity and partially restored by moderate physical activity in mice.

Greene NP, Lee DE, Brown JL, Rosa ME, Brown LA, Perry RA, Henry JN, Washington TA.

Physiol Rep. 2015 Jul;3(7). pii: e12470. doi: 10.14814/phy2.12470.


Mitochondrial dysfunction in aging: Much progress but many unresolved questions.

Payne BA, Chinnery PF.

Biochim Biophys Acta. 2015 Nov;1847(11):1347-53. doi: 10.1016/j.bbabio.2015.05.022. Epub 2015 Jun 4. Review.


Therapeutic effects of adropin on glucose tolerance and substrate utilization in diet-induced obese mice with insulin resistance.

Gao S, McMillan RP, Zhu Q, Lopaschuk GD, Hulver MW, Butler AA.

Mol Metab. 2015 Jan 17;4(4):310-24. doi: 10.1016/j.molmet.2015.01.005. eCollection 2015 Apr.

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