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Items: 1 to 20 of 28


Effect of Cytochrome P450 Metabolites of Arachidonic Acid in Nephrology.

Fan F, Roman RJ.

J Am Soc Nephrol. 2017 Oct;28(10):2845-2855. doi: 10.1681/ASN.2017030252. Epub 2017 Jul 12. Review.


Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target.

Elshenawy OH, Shoieb SM, Mohamed A, El-Kadi AO.

Pharmaceutics. 2017 Feb 20;9(1). pii: E9. doi: 10.3390/pharmaceutics9010009. Review.


Endothelial colony-forming cells ameliorate endothelial dysfunction via secreted factors following ischemia-reperfusion injury.

Collett JA, Mehrotra P, Crone A, Shelley WC, Yoder MC, Basile DP.

Am J Physiol Renal Physiol. 2017 May 1;312(5):F897-F907. doi: 10.1152/ajprenal.00643.2016. Epub 2017 Feb 22.


Upregulation of 20-HETE Synthetic Cytochrome P450 Isoforms by Oxygen-Glucose Deprivation in Cortical Neurons.

Zhang H, Falck JR, Roman RJ, Harder DR, Koehler RC, Yang ZJ.

Cell Mol Neurobiol. 2017 Oct;37(7):1279-1286. doi: 10.1007/s10571-017-0462-8. Epub 2017 Jan 21.


Elevated 20-HETE impairs coronary collateral growth in metabolic syndrome via endothelial dysfunction.

Joseph G, Soler A, Hutcheson R, Hunter I, Bradford C, Hutcheson B, Gotlinger KH, Jiang H, Falck JR, Proctor S, Schwartzman ML, Rocic P.

Am J Physiol Heart Circ Physiol. 2017 Mar 1;312(3):H528-H540. doi: 10.1152/ajpheart.00561.2016. Epub 2016 Dec 23.


Low-dose testosterone protects against renal ischemia-reperfusion injury by increasing renal IL-10-to-TNF-α ratio and attenuating T-cell infiltration.

Patil CN, Wallace K, LaMarca BD, Moulana M, Lopez-Ruiz A, Soljancic A, Juncos LA, Grande JP, Reckelhoff JF.

Am J Physiol Renal Physiol. 2016 Aug 1;311(2):F395-403. doi: 10.1152/ajprenal.00454.2015. Epub 2016 Jun 1.


Molecular mechanisms and cell signaling of 20-hydroxyeicosatetraenoic acid in vascular pathophysiology.

Fan F, Ge Y, Lv W, Elliott MR, Muroya Y, Hirata T, Booz GW, Roman RJ.

Front Biosci (Landmark Ed). 2016 Jun 1;21:1427-63. Review.


Renal Ischemia/Reperfusion Injury in Soluble Epoxide Hydrolase-Deficient Mice.

Zhu Y, Blum M, Hoff U, Wesser T, Fechner M, Westphal C, Gürgen D, Catar RA, Philippe A, Wu K, Bubalo G, Rothe M, Weldon SM, Dragun D, Schunck WH.

PLoS One. 2016 Jan 4;11(1):e0145645. doi: 10.1371/journal.pone.0145645. eCollection 2016.


Estrogen administered after cardiac arrest and cardiopulmonary resuscitation ameliorates acute kidney injury in a sex- and age-specific manner.

Ikeda M, Swide T, Vayl A, Lahm T, Anderson S, Hutchens MP.

Crit Care. 2015 Sep 18;19:332. doi: 10.1186/s13054-015-1049-8.


Deficiency in the Formation of 20-Hydroxyeicosatetraenoic Acid Enhances Renal Ischemia-Reperfusion Injury.

Muroya Y, Fan F, Regner KR, Falck JR, Garrett MR, Juncos LA, Roman RJ.

J Am Soc Nephrol. 2015 Oct;26(10):2460-9. doi: 10.1681/ASN.2014090868. Epub 2015 Feb 2.


Impaired myogenic response and autoregulation of cerebral blood flow is rescued in CYP4A1 transgenic Dahl salt-sensitive rat.

Fan F, Geurts AM, Murphy SR, Pabbidi MR, Jacob HJ, Roman RJ.

Am J Physiol Regul Integr Comp Physiol. 2015 Mar 1;308(5):R379-90. doi: 10.1152/ajpregu.00256.2014. Epub 2014 Dec 24.


Cytochrome P450 eicosanoids in hypertension and renal disease.

Fan F, Muroya Y, Roman RJ.

Curr Opin Nephrol Hypertens. 2015 Jan;24(1):37-46. doi: 10.1097/MNH.0000000000000088. Review.


Role of TRPV1 channels in ischemia/reperfusion-induced acute kidney injury.

Chen L, Markó L, Kaßmann M, Zhu Y, Wu K, Gollasch M.

PLoS One. 2014 Oct 17;9(10):e109842. doi: 10.1371/journal.pone.0109842. eCollection 2014. Erratum in: PLoS One. 2014;9(12):e115469.


Renal endothelial dysfunction in acute kidney ischemia reperfusion injury.

Basile DP, Yoder MC.

Cardiovasc Hematol Disord Drug Targets. 2014;14(1):3-14. Review.


Combined therapy with COX-2 inhibitor and 20-HETE inhibitor reduces colon tumor growth and the adverse effects of ischemic stroke associated with COX-2 inhibition.

Zhang Y, Hoda MN, Zheng X, Li W, Luo P, Maddipati KR, Seki T, Ergul A, Wang MH.

Am J Physiol Regul Integr Comp Physiol. 2014 Sep 15;307(6):R693-703. doi: 10.1152/ajpregu.00422.2013. Epub 2014 Jul 2.


Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway.

Fischer R, Konkel A, Mehling H, Blossey K, Gapelyuk A, Wessel N, von Schacky C, Dechend R, Muller DN, Rothe M, Luft FC, Weylandt K, Schunck WH.

J Lipid Res. 2014 Jun;55(6):1150-64. doi: 10.1194/jlr.M047357. Epub 2014 Mar 16.


20-HETE and blood pressure regulation: clinical implications.

Wu CC, Gupta T, Garcia V, Ding Y, Schwartzman ML.

Cardiol Rev. 2014 Jan-Feb;22(1):1-12. doi: 10.1097/CRD.0b013e3182961659. Review.


Targeting 20-HETE producing enzymes in cancer - rationale, pharmacology, and clinical potential.

Alexanian A, Sorokin A.

Onco Targets Ther. 2013;6:243-55. doi: 10.2147/OTT.S31586. Epub 2013 Mar 26.


Increased susceptibility to kidney injury by transfer of genomic segment from SHR onto Dahl S genetic background.

Regner KR, Harmon AC, Williams JM, Stelloh C, Johnson AC, Kyle PB, Lerch-Gaggl A, White SM, Garrett MR.

Physiol Genomics. 2012 Jun 15;44(12):629-37. doi: 10.1152/physiolgenomics.00015.2012. Epub 2012 May 1.


Role of medullary blood flow in the pathogenesis of renal ischemia-reperfusion injury.

Regner KR, Roman RJ.

Curr Opin Nephrol Hypertens. 2012 Jan;21(1):33-8. doi: 10.1097/MNH.0b013e32834d085a. Review.

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