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Items: 1 to 20 of 211


Oxidative toxicity in diabetes and Alzheimer's disease: mechanisms behind ROS/ RNS generation.

Ahmad W, Ijaz B, Shabbiri K, Ahmed F, Rehman S.

J Biomed Sci. 2017 Sep 19;24(1):76. doi: 10.1186/s12929-017-0379-z. Review.


Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta.

Lopez Sanchez MIG, Waugh HS, Tsatsanis A, Wong BX, Crowston JG, Duce JA, Trounce IA.

Sci Rep. 2017 Aug 29;7(1):9835. doi: 10.1038/s41598-017-10233-0.


A reciprocal relationship between reactive oxygen species and mitochondrial dynamics in neurodegeneration.

Hung CH, Cheng SS, Cheung YT, Wuwongse S, Zhang NQ, Ho YS, Lee SM, Chang RC.

Redox Biol. 2017 Aug 12;14:7-19. doi: 10.1016/j.redox.2017.08.010. [Epub ahead of print]


Interplay of Energetics and ER Stress Exacerbates Alzheimer's Amyloid-β (Aβ) Toxicity in Yeast.

Chen X, Bisschops MMM, Agarwal NR, Ji B, Shanmugavel KP, Petranovic D.

Front Mol Neurosci. 2017 Jul 27;10:232. doi: 10.3389/fnmol.2017.00232. eCollection 2017.


Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus.

Diling C, Tianqiao Y, Jian Y, Chaoqun Z, Ou S, Yizhen X.

Front Pharmacol. 2017 May 12;8:219. doi: 10.3389/fphar.2017.00219. eCollection 2017.


RyR2-Mediated Ca2+ Release and Mitochondrial ROS Generation Partake in the Synaptic Dysfunction Caused by Amyloid β Peptide Oligomers.

SanMartín CD, Veloso P, Adasme T, Lobos P, Bruna B, Galaz J, García A, Hartel S, Hidalgo C, Paula-Lima AC.

Front Mol Neurosci. 2017 Apr 25;10:115. doi: 10.3389/fnmol.2017.00115. eCollection 2017.


Tristetraprolin inhibits mitochondrial function through suppression of α-Synuclein expression in cancer cells.

Vo MT, Choi SH, Lee JH, Hong CH, Kim JS, Lee UH, Chung HM, Lee BJ, Park JW, Cho WJ.

Oncotarget. 2017 Jun 27;8(26):41903-41920. doi: 10.18632/oncotarget.16706.


Mitochondrial Quality Control and Disease: Insights into Ischemia-Reperfusion Injury.

Anzell AR, Maizy R, Przyklenk K, Sanderson TH.

Mol Neurobiol. 2017 Apr 11. doi: 10.1007/s12035-017-0503-9. [Epub ahead of print] Review.


Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases.

Gao J, Wang L, Liu J, Xie F, Su B, Wang X.

Antioxidants (Basel). 2017 Apr 5;6(2). pii: E25. doi: 10.3390/antiox6020025. Review.


Mfn2 protects dopaminergic neurons exposed to paraquat both in vitro and in vivo: Implications for idiopathic Parkinson's disease.

Zhao F, Wang W, Wang C, Siedlak SL, Fujioka H, Tang B, Zhu X.

Biochim Biophys Acta. 2017 Jun;1863(6):1359-1370. doi: 10.1016/j.bbadis.2017.02.016. Epub 2017 Feb 16.


Mitochondrial dynamics in neuronal injury, development and plasticity.

Flippo KH, Strack S.

J Cell Sci. 2017 Feb 15;130(4):671-681. doi: 10.1242/jcs.171017. Epub 2017 Feb 2. Review.


Mitochondrial dynamics changes with age in an APPsw/PS1dE9 mouse model of Alzheimer's disease.

Xu LL, Shen Y, Wang X, Wei LF, Wang P, Yang H, Wang CF, Xie ZH, Bi JZ.

Neuroreport. 2017 Mar 1;28(4):222-228. doi: 10.1097/WNR.0000000000000739.


Metabolic Characterization of Intact Cells Reveals Intracellular Amyloid Beta but Not Its Precursor Protein to Reduce Mitochondrial Respiration.

Schaefer PM, von Einem B, Walther P, Calzia E, von Arnim CA.

PLoS One. 2016 Dec 22;11(12):e0168157. doi: 10.1371/journal.pone.0168157. eCollection 2016.


Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.

Cai Q, Tammineni P.

J Alzheimers Dis. 2017;57(4):1087-1103. doi: 10.3233/JAD-160726.


Phlorofucofuroeckol Improves Glutamate-Induced Neurotoxicity through Modulation of Oxidative Stress-Mediated Mitochondrial Dysfunction in PC12 Cells.

Kim JJ, Kang YJ, Shin SA, Bak DH, Lee JW, Lee KB, Yoo YC, Kim DK, Lee BH, Kim DW, Lee J, Jo EK, Yuk JM.

PLoS One. 2016 Sep 26;11(9):e0163433. doi: 10.1371/journal.pone.0163433. eCollection 2016.


Antioxidants Rescue Mitochondrial Transport in Differentiated Alzheimer's Disease Trans-Mitochondrial Cybrid Cells.

Yu Q, Fang D, Swerdlow RH, Yu H, Chen JX, Yan SS.

J Alzheimers Dis. 2016 Sep 6;54(2):679-90. doi: 10.3233/JAD-160532.


Protective effects of a natural product, curcumin, against amyloid β induced mitochondrial and synaptic toxicities in Alzheimer's disease.

Reddy PH, Manczak M, Yin X, Grady MC, Mitchell A, Kandimalla R, Kuruva CS.

J Investig Med. 2016 Dec;64(8):1220-1234. Epub 2016 Aug 12.

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