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How does leptin restore euglycemia in insulin-deficient diabetes?

Oberlin D, Buettner C.

J Clin Invest. 2017 Feb 1;127(2):450-453. doi: 10.1172/JCI91880.


Impairment of neurovascular coupling in Type 1 Diabetes Mellitus in rats is prevented by pancreatic islet transplantation and reversed by a semi-selective PKC inhibitor.

Vetri F, Qi M, Xu H, Oberholzer J, Paisansathan C.

Brain Res. 2017 Jan 15;1655:48-54. doi: 10.1016/j.brainres.2016.11.012.


Challenges in Modelling Hypoglycaemia-Associated Autonomic Failure: A Review of Human and Animal Studies.

Senthilkumaran M, Zhou XF, Bobrovskaya L.

Int J Endocrinol. 2016;2016:9801640. Review.


Predictors of hypoglycemia in insulin-treated patients with type 2 diabetes mellitus in Basrah.

Nassar DT, Habib OS, Mansour AA.

World J Diabetes. 2016 Oct 15;7(18):470-480.


Acute Effects of Oral Dehydroepiandrosterone on Counterregulatory Responses During Repeated Hypoglycemia in Healthy Humans.

Mikeladze M, Hedrington MS, Joy N, Tate DB, Younk LM, Davis I, Davis SN.

Diabetes. 2016 Oct;65(10):3161-70. doi: 10.2337/db16-0406.


Coming of age: the artificial pancreas for type 1 diabetes.

Thabit H, Hovorka R.

Diabetologia. 2016 Sep;59(9):1795-805. doi: 10.1007/s00125-016-4022-4. Review.


Effects of γ-Aminobutyric Acid A Receptor Activation on Counterregulatory Responses to Subsequent Exercise in Individuals With Type 1 Diabetes.

Hedrington MS, Mikeladze M, Tate DB, Younk LM, Davis I, Davis SN.

Diabetes. 2016 Sep;65(9):2754-9. doi: 10.2337/db16-0207.


Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis.

Winnick JJ, Kraft G, Gregory JM, Edgerton DS, Williams P, Hajizadeh IA, Kamal MZ, Smith M, Farmer B, Scott M, Neal D, Donahue EP, Allen E, Cherrington AD.

J Clin Invest. 2016 Jun 1;126(6):2236-48. doi: 10.1172/JCI79895.


Cost effectiveness and value of information analyses of islet cell transplantation in the management of 'unstable' type 1 diabetes mellitus.

Wallner K, Shapiro AM, Senior PA, McCabe C.

BMC Endocr Disord. 2016 Apr 9;16:17. doi: 10.1186/s12902-016-0097-7.


The Impact of Real-Time Continuous Glucose Monitoring in Patients 65 Years and Older.

Polonsky WH, Peters AL, Hessler D.

J Diabetes Sci Technol. 2016 Jun 28;10(4):892-7. doi: 10.1177/1932296816643542.


Biological Characterization of Gene Response to Insulin-Induced Hypoglycemia in Mouse Retina.

Emery M, Nanchen N, Preitner F, Ibberson M, Roduit R.

PLoS One. 2016 Feb 26;11(2):e0150266. doi: 10.1371/journal.pone.0150266.


Event and Cost Offsets of Switching 20% of the Type 1 Diabetes Population in Germany From Multiple Daily Injections to Continuous Subcutaneous Insulin Infusion: A 4-Year Simulation Model.

Zöllner YF, Ziegler R, Stüve M, Krumreich J, Schauf M.

J Diabetes Sci Technol. 2016 Aug 22;10(5):1142-8. doi: 10.1177/1932296816633720.


Day-and-Night Hybrid Closed-Loop Insulin Delivery in Adolescents With Type 1 Diabetes: A Free-Living, Randomized Clinical Trial.

Tauschmann M, Allen JM, Wilinska ME, Thabit H, Stewart Z, Cheng P, Kollman C, Acerini CL, Dunger DB, Hovorka R.

Diabetes Care. 2016 Jul;39(7):1168-74. doi: 10.2337/dc15-2078.


Intranasal Glucagon for Treatment of Insulin-Induced Hypoglycemia in Adults With Type 1 Diabetes: A Randomized Crossover Noninferiority Study.

Rickels MR, Ruedy KJ, Foster NC, Piché CA, Dulude H, Sherr JL, Tamborlane WV, Bethin KE, DiMeglio LA, Wadwa RP, Ahmann AJ, Haller MJ, Nathan BM, Marcovina SM, Rampakakis E, Meng L, Beck RW; T1D Exchange Intranasal Glucagon Investigators..

Diabetes Care. 2016 Feb;39(2):264-70. doi: 10.2337/dc15-1498.


Brain glucose metabolism during hypoglycemia in type 1 diabetes: insights from functional and metabolic neuroimaging studies.

Rooijackers HM, Wiegers EC, Tack CJ, van der Graaf M, de Galan BE.

Cell Mol Life Sci. 2016 Feb;73(4):705-22. doi: 10.1007/s00018-015-2079-8. Review.


Leptin acts in the brain to influence hypoglycemic counterregulation: disparate effects of acute and recurrent hypoglycemia on glucagon release.

Reno CM, Ding Y, Sherwin R.

Am J Physiol Endocrinol Metab. 2015 Dec 15;309(12):E960-7. doi: 10.1152/ajpendo.00361.2015.


Physical Activity Capture Technology With Potential for Incorporation Into Closed-Loop Control for Type 1 Diabetes.

Dadlani V, Levine JA, McCrady-Spitzer SK, Dassau E, Kudva YC.

J Diabetes Sci Technol. 2015 Oct 18;9(6):1208-16. doi: 10.1177/1932296815609949. Review.

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