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Items: 18


Skeletal muscle metabolic adaptations to endurance exercise training are attainable in mice with simvastatin treatment.

Southern WM, Nichenko AS, Shill DD, Spencer CC, Jenkins NT, McCully KK, Call JA.

PLoS One. 2017 Feb 16;12(2):e0172551. doi: 10.1371/journal.pone.0172551. eCollection 2017.


The Impact of Exercise on Statin-Associated Skeletal Muscle Myopathy.

Chung HR, Vakil M, Munroe M, Parikh A, Meador BM, Wu PT, Jeong JH, Woods JA, Wilund KR, Boppart MD.

PLoS One. 2016 Dec 9;11(12):e0168065. doi: 10.1371/journal.pone.0168065. eCollection 2016.


A short-term statin treatment changes the contractile properties of fast-twitch skeletal muscles.

Piette AB, Dufresne SS, Frenette J.

BMC Musculoskelet Disord. 2016 Oct 28;17(1):449.


Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training.

Bowen TS, Schuler G, Adams V.

J Cachexia Sarcopenia Muscle. 2015 Sep;6(3):197-207. doi: 10.1002/jcsm.12043. Epub 2015 Jun 3. Review.


Statin-Induced Increases in Atrophy Gene Expression Occur Independently of Changes in PGC1α Protein and Mitochondrial Content.

Goodman CA, Pol D, Zacharewicz E, Lee-Young RS, Snow RJ, Russell AP, McConell GK.

PLoS One. 2015 May 28;10(5):e0128398. doi: 10.1371/journal.pone.0128398. eCollection 2015.


Statin use and risk of diabetes mellitus.

Chogtu B, Magazine R, Bairy KL.

World J Diabetes. 2015 Mar 15;6(2):352-7. doi: 10.4239/wjd.v6.i2.352. Review.


Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management.

Stroes ES, Thompson PD, Corsini A, Vladutiu GD, Raal FJ, Ray KK, Roden M, Stein E, Tokgözoğlu L, Nordestgaard BG, Bruckert E, De Backer G, Krauss RM, Laufs U, Santos RD, Hegele RA, Hovingh GK, Leiter LA, Mach F, März W, Newman CB, Wiklund O, Jacobson TA, Catapano AL, Chapman MJ, Ginsberg HN; European Atherosclerosis Society Consensus Panel.

Eur Heart J. 2015 May 1;36(17):1012-22. doi: 10.1093/eurheartj/ehv043. Epub 2015 Feb 18. Review.


Statin myalgia is not associated with reduced muscle strength, mass or protein turnover in older male volunteers, but is allied with a slowing of time to peak power output, insulin resistance and differential muscle mRNA expression.

Mallinson JE, Marimuthu K, Murton A, Selby A, Smith K, Constantin-Teodosiu D, Rennie MJ, Greenhaff PL.

J Physiol. 2015 Mar 1;593(5):1239-57. doi: 10.1113/jphysiol.2014.285577. Epub 2015 Jan 26.


Human isoprenoid synthase enzymes as therapeutic targets.

Park J, Matralis AN, Berghuis AM, Tsantrizos YS.

Front Chem. 2014 Jul 22;2:50. doi: 10.3389/fchem.2014.00050. eCollection 2014. Review.


Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.

Peng H, Luo P, Li Y, Wang C, Liu X, Ye Z, Li C, Lou T.

PLoS One. 2013 Nov 14;8(11):e80009. doi: 10.1371/journal.pone.0080009. eCollection 2013.


Regulation of muscle pyruvate dehydrogenase complex in insulin resistance: effects of exercise and dichloroacetate.

Constantin-Teodosiu D.

Diabetes Metab J. 2013 Oct;37(5):301-14. doi: 10.4093/dmj.2013.37.5.301. Review.


Pharmacological activation of the pyruvate dehydrogenase complex reduces statin-mediated upregulation of FOXO gene targets and protects against statin myopathy in rodents.

Mallinson JE, Constantin-Teodosiu D, Glaves PD, Martin EA, Davies WJ, Westwood FR, Sidaway JE, Greenhaff PL.

J Physiol. 2012 Dec 15;590(24):6389-402. doi: 10.1113/jphysiol.2012.238022. Epub 2012 Oct 8.


Molecular and cellular mechanisms of skeletal muscle atrophy: an update.

Fanzani A, Conraads VM, Penna F, Martinet W.

J Cachexia Sarcopenia Muscle. 2012 Sep;3(3):163-79. doi: 10.1007/s13539-012-0074-6. Epub 2012 Jun 7.


Ontogeny of proteolytic signaling and antioxidant capacity in fetal and neonatal diaphragm.

Song Y, Pillow JJ.

Anat Rec (Hoboken). 2012 May;295(5):864-71. doi: 10.1002/ar.22436. Epub 2012 Mar 7.


Simvastatin represses protein synthesis in the muscle-derived C₂C₁₂ cell line with a concomitant reduction in eukaryotic initiation factor 2B expression.

Tuckow AP, Jefferson SJ, Kimball SR, Jefferson LS.

Am J Physiol Endocrinol Metab. 2011 Mar;300(3):E564-70. doi: 10.1152/ajpendo.00383.2010. Epub 2011 Jan 11.


Statin therapy and the expression of genes that regulate calcium homeostasis and membrane repair in skeletal muscle.

Draeger A, Sanchez-Freire V, Monastyrskaya K, Hoppeler H, Mueller M, Breil F, Mohaupt MG, Babiychuk EB.

Am J Pathol. 2010 Jul;177(1):291-9. doi: 10.2353/ajpath.2010.091140. Epub 2010 May 20.


Low-dose dexamethasone prevents endotoxaemia-induced muscle protein loss and impairment of carbohydrate oxidation in rat skeletal muscle.

Crossland H, Constantin-Teodosiu D, Greenhaff PL, Gardiner SM.

J Physiol. 2010 Apr 15;588(Pt 8):1333-47. doi: 10.1113/jphysiol.2009.183699. Epub 2010 Feb 22.


The battle to keep or lose skeletal muscle with ageing.

Kjaer M, Jespersen JG.

J Physiol. 2009 Jan 15;587(1):1-2. doi: 10.1113/jphysiol.2008.167049. No abstract available.

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