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Items: 1 to 20 of 39


Targeting Mitochondrial Dysfunction for the Treatment of Diabetic Complications: Pharmacological Interventions through Natural Products.

Kaikini AA, Kanchan DM, Nerurkar UN, Sathaye S.

Pharmacogn Rev. 2017 Jul-Sep;11(22):128-135. doi: 10.4103/phrev.phrev_41_16. Review.


Identification of differentially expressed genes through RNA sequencing in goats (Capra hircus) at different postnatal stages.

Lin Y, Zhu J, Wang Y, Li Q, Lin S.

PLoS One. 2017 Aug 11;12(8):e0182602. doi: 10.1371/journal.pone.0182602. eCollection 2017.


Active subfractions of Abelmoschus esculentus substantially prevent free fatty acid-induced β cell apoptosis via inhibiting dipeptidyl peptidase-4.

Huang CN, Wang CJ, Lee YJ, Peng CH.

PLoS One. 2017 Jul 17;12(7):e0180285. doi: 10.1371/journal.pone.0180285. eCollection 2017.


Suppression of Hepatic Epithelial-to-Mesenchymal Transition by Melittin via Blocking of TGFβ/Smad and MAPK-JNK Signaling Pathways.

Park JH, Park B, Park KK.

Toxins (Basel). 2017 Apr 13;9(4). pii: E138. doi: 10.3390/toxins9040138.


Compound K attenuates glucose intolerance and hepatic steatosis through AMPK-dependent pathways in type 2 diabetic OLETF rats.

Hwang YC, Oh DH, Choi MC, Lee SY, Ahn KJ, Chung HY, Lim SJ, Chung SH, Jeong IK.

Korean J Intern Med. 2018 Mar;33(2):347-355. doi: 10.3904/kjim.2015.208. Epub 2017 Feb 1.


Protein kinases: mechanisms and downstream targets in inflammation-mediated obesity and insulin resistance.

Nandipati KC, Subramanian S, Agrawal DK.

Mol Cell Biochem. 2017 Feb;426(1-2):27-45. doi: 10.1007/s11010-016-2878-8. Epub 2016 Nov 21. Review.


Berberine Alleviates Olanzapine-Induced Adipogenesis via the AMPKα-SREBP Pathway in 3T3-L1 Cells.

Li Y, Zhao X, Feng X, Liu X, Deng C, Hu CH.

Int J Mol Sci. 2016 Nov 9;17(11). pii: E1865.


Protective effect of α-lipoic acid against radiation-induced fibrosis in mice.

Ryu SH, Park EY, Kwak S, Heo SH, Ryu JW, Park JH, Choi KC, Lee SW.

Oncotarget. 2016 Mar 29;7(13):15554-65. doi: 10.18632/oncotarget.6952.


Distinct Time Course of the Decrease in Hepatic AMP-Activated Protein Kinase and Akt Phosphorylation in Mice Fed a High Fat Diet.

Shiwa M, Yoneda M, Okubo H, Ohno H, Kobuke K, Monzen Y, Kishimoto R, Nakatsu Y, Asano T, Kohno N.

PLoS One. 2015 Aug 12;10(8):e0135554. doi: 10.1371/journal.pone.0135554. eCollection 2015.


Activation of hepatic CREBH and Insig signaling in the anti-hypertriglyceridemic mechanism of R-α-lipoic acid.

Tong X, Christian P, Zhao M, Wang H, Moreau R, Su Q.

J Nutr Biochem. 2015 Sep;26(9):921-8. doi: 10.1016/j.jnutbio.2015.03.011. Epub 2015 May 7.


Complementary Cholesterol-Lowering Response of a Phytosterol/α-Lipoic Acid Combination in Obese Zucker Rats.

Rideout TC, Carrier B, Wen S, Raslawsky A, Browne RW, Harding SV.

J Diet Suppl. 2016;13(3):283-99. doi: 10.3109/19390211.2015.1008616. Epub 2015 Feb 9.


Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-BP1 Pathway.

Lv C, Wu C, Zhou YH, Shao Y, Wang G, Wang QY.

Int J Endocrinol. 2014;2014:658589. doi: 10.1155/2014/658589. Epub 2014 Oct 30.


Nonalcoholic Fatty liver disease: pathogenesis and therapeutics from a mitochondria-centric perspective.

Gusdon AM, Song KX, Qu S.

Oxid Med Cell Longev. 2014;2014:637027. doi: 10.1155/2014/637027. Epub 2014 Oct 13. Review.


Alpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice.

Yang Y, Li W, Liu Y, Li Y, Gao L, Zhao JJ.

Acta Pharmacol Sin. 2014 Oct;35(10):1285-92. doi: 10.1038/aps.2014.64. Epub 2014 Aug 25.


Signal transductions and nonalcoholic fatty liver: a mini-review.

Zeng L, Tang WJ, Yin JJ, Zhou BJ.

Int J Clin Exp Med. 2014 Jul 15;7(7):1624-31. eCollection 2014. Review.


Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1 c pathway.

Lee JH, Jung JY, Jang EJ, Jegal KH, Moon SY, Ku SK, Kang SH, Cho IJ, Park SJ, Lee JR, Zhao RJ, Kim SC, Kim YW.

Exp Biol Med (Maywood). 2015 Apr;240(4):508-18. doi: 10.1177/1535370214547123. Epub 2014 Aug 14.


Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases.

Rana S, Blowers EC, Natarajan A.

J Med Chem. 2015 Jan 8;58(1):2-29. doi: 10.1021/jm401994c. Epub 2014 Aug 28. Review.


Transcriptional regulation of fibroblast growth factor 21 expression.

Bae KH, Kim JG, Park KG.

Endocrinol Metab (Seoul). 2014 Jun;29(2):105-11. doi: 10.3803/EnM.2014.29.2.105. Review.


AMPK activation: a therapeutic target for type 2 diabetes?

Coughlan KA, Valentine RJ, Ruderman NB, Saha AK.

Diabetes Metab Syndr Obes. 2014 Jun 24;7:241-53. doi: 10.2147/DMSO.S43731. eCollection 2014. Review.


Crude extracts from Lycium barbarum suppress SREBP-1c expression and prevent diet-induced fatty liver through AMPK activation.

Li W, Li Y, Wang Q, Yang Y.

Biomed Res Int. 2014;2014:196198. doi: 10.1155/2014/196198. Epub 2014 Jun 10.

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