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Items: 18


Pathophysiological Functions of Rnd3/RhoE.

Jie W, Andrade KC, Lin X, Yang X, Yue X, Chang J.

Compr Physiol. 2015 Dec 15;6(1):169-86. doi: 10.1002/cphy.c150018. Review.


High Mobility Group B Proteins, Their Partners, and Other Redox Sensors in Ovarian and Prostate Cancer.

Barreiro-Alonso A, Lamas-Maceiras M, Rodríguez-Belmonte E, Vizoso-Vázquez Á, Quindós M, Cerdán ME.

Oxid Med Cell Longev. 2016;2016:5845061. doi: 10.1155/2016/5845061. Epub 2015 Nov 23. Review.


RhoE is required for contact inhibition and negatively regulates tumor initiation and progression.

Hernández-Sánchez M, Poch E, Guasch RM, Ortega J, López-Almela I, Palmero I, Pérez-Roger I.

Oncotarget. 2015 Jul 10;6(19):17479-90.


The effect of Rho kinase inhibition on long-term keratinocyte proliferation is rapid and conditional.

Chapman S, McDermott DH, Shen K, Jang MK, McBride AA.

Stem Cell Res Ther. 2014 Apr 28;5(2):60. doi: 10.1186/scrt449.


Small GTPase RhoE/Rnd3 is a critical regulator of Notch1 signaling.

Zhu Z, Todorova K, Lee KK, Wang J, Kwon E, Kehayov I, Kim HG, Kolev V, Dotto GP, Lee SW, Mandinova A.

Cancer Res. 2014 Apr 1;74(7):2082-93. doi: 10.1158/0008-5472.CAN-12-0452. Epub 2014 Feb 13.


Noncanonical NOTCH signaling limits self-renewal of human epithelial and induced pluripotent stem cells through ROCK activation.

Yugawa T, Nishino K, Ohno S, Nakahara T, Fujita M, Goshima N, Umezawa A, Kiyono T.

Mol Cell Biol. 2013 Nov;33(22):4434-47. doi: 10.1128/MCB.00577-13. Epub 2013 Sep 9.


Boosting and rescuing epidermal superior population from fresh keratinocyte cultures.

Cerqueira MT, Frias AM, Reis RL, Marques AP.

Stem Cells Dev. 2014 Jan 1;23(1):34-43. doi: 10.1089/scd.2013.0038. Epub 2013 Sep 24.


The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1.

Dubash AD, Koetsier JL, Amargo EV, Najor NA, Harmon RM, Green KJ.

J Cell Biol. 2013 Aug 19;202(4):653-66. doi: 10.1083/jcb.201304133. Epub 2013 Aug 12.


RhoJ modulates melanoma invasion by altering actin cytoskeletal dynamics.

Ho H, Soto Hopkin A, Kapadia R, Vasudeva P, Schilling J, Ganesan AK.

Pigment Cell Melanoma Res. 2013 Mar;26(2):218-25. doi: 10.1111/pcmr.12058. Epub 2013 Jan 7.


Aurora kinase-A deficiency during skin development impairs cell division and stratification.

Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR.

J Invest Dermatol. 2013 Jan;133(1):78-86. doi: 10.1038/jid.2012.249. Epub 2012 Jul 26.


The GTPase-deficient Rnd proteins are stabilized by their effectors.

Goh LL, Manser E.

J Biol Chem. 2012 Sep 7;287(37):31311-20. doi: 10.1074/jbc.M111.327056. Epub 2012 Jul 17.


Desmoglein 3 acting as an upstream regulator of Rho GTPases, Rac-1/Cdc42 in the regulation of actin organisation and dynamics.

Tsang SM, Brown L, Gadmor H, Gammon L, Fortune F, Wheeler A, Wan H.

Exp Cell Res. 2012 Nov 1;318(18):2269-83. doi: 10.1016/j.yexcr.2012.07.002. Epub 2012 Jul 13.


Rho kinase inhibitor Y-27632 prolongs the life span of adult human keratinocytes, enhances skin equivalent development, and facilitates lentiviral transduction.

van den Bogaard EH, Rodijk-Olthuis D, Jansen PA, van Vlijmen-Willems IM, van Erp PE, Joosten I, Zeeuwen PL, Schalkwijk J.

Tissue Eng Part A. 2012 Sep;18(17-18):1827-36. doi: 10.1089/ten.TEA.2011.0616. Epub 2012 Jun 5.


RhoE is regulated by cyclic AMP and promotes fusion of human BeWo choriocarcinoma cells.

Collett GP, Goh XF, Linton EA, Redman CW, Sargent IL.

PLoS One. 2012;7(1):e30453. doi: 10.1371/journal.pone.0030453. Epub 2012 Jan 17.


Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis.

Simpson CL, Patel DM, Green KJ.

Nat Rev Mol Cell Biol. 2011 Aug 23;12(9):565-80. doi: 10.1038/nrm3175. Review.


Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling.

Gabet AS, Coulon S, Fricot A, Vandekerckhove J, Chang Y, Ribeil JA, Lordier L, Zermati Y, Asnafi V, Belaid Z, Debili N, Vainchenker W, Varet B, Hermine O, Courtois G.

Cell Death Differ. 2011 Apr;18(4):678-89. doi: 10.1038/cdd.2010.140. Epub 2010 Nov 12.


The TRPV4 channel contributes to intercellular junction formation in keratinocytes.

Sokabe T, Fukumi-Tominaga T, Yonemura S, Mizuno A, Tominaga M.

J Biol Chem. 2010 Jun 11;285(24):18749-58. doi: 10.1074/jbc.M110.103606. Epub 2010 Apr 22.


Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation.

Lock FE, Hotchin NA.

PLoS One. 2009 Dec 4;4(12):e8190. doi: 10.1371/journal.pone.0008190.

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