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Effects of multiple genetic loci on the pathogenesis from serum urate to gout.

Dong Z, Zhou J, Jiang S, Li Y, Zhao D, Yang C, Ma Y, Wang Y, He H, Ji H, Yang Y, Wang X, Xu X, Pang Y, Zou H, Jin L, Wang J.

Sci Rep. 2017 Mar 2;7:43614. doi: 10.1038/srep43614.


Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study.

Chittoor G, Haack K, Mehta NR, Laston S, Cole SA, Comuzzie AG, Butte NF, Voruganti VS.

BMC Med Genet. 2017 Jan 17;18(1):6. doi: 10.1186/s12881-016-0366-3.


Natural Products Improving Hyperuricemia with Hepatorenal Dual Effects.

Hao S, Zhang C, Song H.

Evid Based Complement Alternat Med. 2016;2016:7390504. Review.


The epidemiology and treatment of gout.

McGill NW.

Open Access Rheumatol. 2011 Dec 20;3:73-82. Review.


Jump into a New Fold-A Homology Based Model for the ABCG2/BCRP Multidrug Transporter.

László L, Sarkadi B, Hegedűs T.

PLoS One. 2016 Oct 14;11(10):e0164426. doi: 10.1371/journal.pone.0164426.


Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney.

Miner J, Tan PK, Hyndman D, Liu S, Iverson C, Nanavati P, Hagerty DT, Manhard K, Shen Z, Girardet JL, Yeh LT, Terkeltaub R, Quart B.

Arthritis Res Ther. 2016 Oct 3;18(1):214. Erratum in: Arthritis Res Ther. 2016 Oct 12;18(1):236.


Mechanism of high affinity inhibition of the human urate transporter URAT1.

Tan PK, Ostertag TM, Miner JN.

Sci Rep. 2016 Oct 7;6:34995. doi: 10.1038/srep34995.


An old disease with new insights: Update on diagnosis and treatment of gout.

Bitik B, Öztürk MA.

Eur J Rheumatol. 2014 Jun;1(2):72-77. Review.


Epidermal growth factor gene is a newly identified candidate gene for gout.

Han L, Cao C, Jia Z, Liu S, Liu Z, Xin R, Wang C, Li X, Ren W, Wang X, Li C.

Sci Rep. 2016 Aug 10;6:31082. doi: 10.1038/srep31082.


Serum Uric Acid Levels were Dynamically Coupled with Hemoglobin A1c in the Development of Type 2 Diabetes.

Wei F, Chang B, Yang X, Wang Y, Chen L, Li WD.

Sci Rep. 2016 Jun 22;6:28549. doi: 10.1038/srep28549.


Urate Handling in the Human Body.

Hyndman D, Liu S, Miner JN.

Curr Rheumatol Rep. 2016 Jun;18(6):34. doi: 10.1007/s11926-016-0587-7. Review.


GWAS and transcriptional analysis prioritize ITPR1 and CNTN4 for a serum uric acid 3p26 QTL in Mexican Americans.

Chittoor G, Kent JW Jr, Almeida M, Puppala S, Farook VS, Cole SA, Haack K, Göring HH, MacCluer JW, Curran JE, Carless MA, Johnson MP, Moses EK, Almasy L, Mahaney MC, Lehman DM, Duggirala R, Comuzzie AG, Blangero J, Voruganti VS.

BMC Genomics. 2016 Apr 2;17:276. doi: 10.1186/s12864-016-2594-5.


Genome wide association study of uric acid in Indian population and interaction of identified variants with Type 2 diabetes.

Giri AK, Banerjee P, Chakraborty S, Kauser Y, Undru A, Roy S, Parekatt V, Ghosh S, Tandon N, Bharadwaj D.

Sci Rep. 2016 Feb 23;6:21440. doi: 10.1038/srep21440.


The effects of URAT1/SLC22A12 nonfunctional variants, R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression.

Sakiyama M, Matsuo H, Shimizu S, Nakashima H, Nakamura T, Nakayama A, Higashino T, Naito M, Suma S, Hishida A, Satoh T, Sakurai Y, Takada T, Ichida K, Ooyama H, Shimizu T, Shinomiya N.

Sci Rep. 2016 Jan 29;6:20148. doi: 10.1038/srep20148.


Gout in Older Adults: The Atherosclerosis Risk in Communities Study.

Burke BT, Köttgen A, Law A, Grams M, Baer AN, Coresh J, McAdams-DeMarco MA.

J Gerontol A Biol Sci Med Sci. 2016 Apr;71(4):536-42. doi: 10.1093/gerona/glv120.


Allelic Variation of Risk for Anxiety Symptoms Moderates the Relation Between Adolescent Safety Behaviors and Social Anxiety Symptoms.

Thomas SA, Weeks JW, Dougherty LR, Lipton MF, Daruwala SE, Kline K, De Los Reyes A.

J Psychopathol Behav Assess. 2015 Dec 1;37(4):597-610.


A meta-analysis of the associations between the Q141K and Q126X ABCG2 gene variants and gout risk.

Li R, Miao L, Qin L, Xiang Y, Zhang X, Peng H, Mailamuguli, Sun Y, Yao H.

Int J Clin Exp Pathol. 2015 Sep 1;8(9):9812-23.


The anatomical distribution of genetic associations.

Wells A, Kopp N, Xu X, O'Brien DR, Yang W, Nehorai A, Adair-Kirk TL, Kopan R, Dougherty JD.

Nucleic Acids Res. 2015 Dec 15;43(22):10804-20. doi: 10.1093/nar/gkv1262.


Correlation of GLUT9 Polymorphisms With Gout Risk.

Meng Q, Yue J, Shang M, Shan Q, Qi J, Mao Z, Li J, Zhang F, Wang B, Zhao T, Wang W.

Medicine (Baltimore). 2015 Nov;94(44):e1742. doi: 10.1097/MD.0000000000001742. Review.

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