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Quantifying Limits on Replication, Death, and Quiescence of Mycobacterium tuberculosis in Mice.

McDaniel MM, Krishna N, Handagama WG, Eda S, Ganusov VV.

Front Microbiol. 2016 Jun 14;7:862. doi: 10.3389/fmicb.2016.00862.


Control of T cell antigen reactivity via programmed TCR downregulation.

Gallegos AM, Xiong H, Leiner IM, Sušac B, Glickman MS, Pamer EG, van Heijst JW.

Nat Immunol. 2016 Apr;17(4):379-86. doi: 10.1038/ni.3386.


Antigen Export Reduces Antigen Presentation and Limits T Cell Control of M. tuberculosis.

Srivastava S, Grace PS, Ernst JD.

Cell Host Microbe. 2016 Jan 13;19(1):44-54. doi: 10.1016/j.chom.2015.12.003.


Major Loci on Chromosomes 8q and 3q Control Interferon γ Production Triggered by Bacillus Calmette-Guerin and 6-kDa Early Secretory Antigen Target, Respectively, in Various Populations.

Jabot-Hanin F, Cobat A, Feinberg J, Grange G, Remus N, Poirier C, Boland-Auge A, Besse C, Bustamante J, Boisson-Dupuis S, Casanova JL, Schurr E, Alcaïs A, Hoal EG, Delacourt C, Abel L.

J Infect Dis. 2016 Apr 1;213(7):1173-9. doi: 10.1093/infdis/jiv757.


Mycolic acid-specific T cells protect against Mycobacterium tuberculosis infection in a humanized transgenic mouse model.

Zhao J, Siddiqui S, Shang S, Bian Y, Bagchi S, He Y, Wang CR.

Elife. 2015 Dec 10;4. pii: e08525. doi: 10.7554/eLife.08525.


Suboptimal Antigen Presentation Contributes to Virulence of Mycobacterium tuberculosis In Vivo.

Grace PS, Ernst JD.

J Immunol. 2016 Jan 1;196(1):357-64. doi: 10.4049/jimmunol.1501494.


Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection.

Nunes-Alves C, Booty MG, Carpenter SM, Rothchild AC, Martin CJ, Desjardins D, Steblenko K, Kløverpris HN, Madansein R, Ramsuran D, Leslie A, Correia-Neves M, Behar SM.

PLoS Pathog. 2015 May 6;11(5):e1004849. doi: 10.1371/journal.ppat.1004849. Erratum in: PLoS Pathog. 2015 Sep;11(9):e1005144.


ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis.

Moguche AO, Shafiani S, Clemons C, Larson RP, Dinh C, Higdon LE, Cambier CJ, Sissons JR, Gallegos AM, Fink PJ, Urdahl KB.

J Exp Med. 2015 May 4;212(5):715-28. doi: 10.1084/jem.20141518.


ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-6 and Reduces Pulmonary Infection with Virulent Mycobacterium tuberculosis.

Silva-Sánchez A, Meza-Pérez S, Flores-Langarica A, Donis-Maturano L, Estrada-García I, Calderón-Amador J, Hernández-Pando R, Idoyaga J, Steinman RM, Flores-Romo L.

PLoS One. 2015 Apr 27;10(4):e0124828. doi: 10.1371/journal.pone.0124828.


Understanding and overcoming the barriers to T cell-mediated immunity against tuberculosis.

Urdahl KB.

Semin Immunol. 2014 Dec;26(6):578-87. doi: 10.1016/j.smim.2014.10.003. Review.


Tuberculosis vaccines and prevention of infection.

Hawn TR, Day TA, Scriba TJ, Hatherill M, Hanekom WA, Evans TG, Churchyard GJ, Kublin JG, Bekker LG, Self SG.

Microbiol Mol Biol Rev. 2014 Dec;78(4):650-71. doi: 10.1128/MMBR.00021-14. Review.


Striking the Right Balance Determines TB or Not TB.

BoseDasgupta S, Pieters J.

Front Immunol. 2014 Oct 8;5:455. doi: 10.3389/fimmu.2014.00455. Review.


Beyond macrophages: the diversity of mononuclear cells in tuberculosis.

Srivastava S, Ernst JD, Desvignes L.

Immunol Rev. 2014 Nov;262(1):179-92. doi: 10.1111/imr.12217. Review.


Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: immunity interruptus.

Behar SM, Carpenter SM, Booty MG, Barber DL, Jayaraman P.

Semin Immunol. 2014 Dec;26(6):559-77. doi: 10.1016/j.smim.2014.09.003. Review.


Mouse model of tuberculosis.

Cooper AM.

Cold Spring Harb Perspect Med. 2014 Sep 25;5(2):a018556. doi: 10.1101/cshperspect.a018556. Review.


Communication between Human Dendritic Cell Subsets in Tuberculosis: Requirements for Naive CD4(+) T Cell Stimulation.

Lozza L, Farinacci M, Bechtle M, Stäber M, Zedler U, Baiocchini A, Del Nonno F, Kaufmann SH.

Front Immunol. 2014 Jul 14;5:324. doi: 10.3389/fimmu.2014.00324.


Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge.

Darrah PA, Bolton DL, Lackner AA, Kaushal D, Aye PP, Mehra S, Blanchard JL, Didier PJ, Roy CJ, Rao SS, Hokey DA, Scanga CA, Sizemore DR, Sadoff JC, Roederer M, Seder RA.

J Immunol. 2014 Aug 15;193(4):1799-811. doi: 10.4049/jimmunol.1400676.


Cell-to-cell transfer of M. tuberculosis antigens optimizes CD4 T cell priming.

Srivastava S, Ernst JD.

Cell Host Microbe. 2014 Jun 11;15(6):741-52. doi: 10.1016/j.chom.2014.05.007.


Immunology of tuberculosis.

Bozzano F, Marras F, De Maria A.

Mediterr J Hematol Infect Dis. 2014 Apr 7;6(1):e2014027. doi: 10.4084/MJHID.2014.027. Review.

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