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Items: 1 to 20 of 46

1.

Ectopic Phosphorylated Creb Marks Dedifferentiated Proximal Tubules in Cystic Kidney Disease.

Puri P, Schaefer CM, Bushnell D, Taglienti ME, Kreidberg JA, Yoder BK, Bates CM.

Am J Pathol. 2018 Jan;188(1):84-94. doi: 10.1016/j.ajpath.2017.09.015. Epub 2017 Oct 26.

PMID:
29107072
2.

Gα12 is required for renal cystogenesis induced by Pkd1 inactivation.

Wu Y, Xu JX, El-Jouni W, Lu T, Li S, Wang Q, Tran M, Yu W, Wu M, Barrera IE, Bonventre JV, Zhou J, Denker BM, Kong T.

J Cell Sci. 2016 Oct 1;129(19):3675-3684. Epub 2016 Aug 5.

3.

Differences in the timing and magnitude of Pkd1 gene deletion determine the severity of polycystic kidney disease in an orthologous mouse model of ADPKD.

Rogers KA, Moreno SE, Smith LA, Husson H, Bukanov NO, Ledbetter SR, Budman Y, Lu Y, Wang B, Ibraghimov-Beskrovnaya O, Natoli TA.

Physiol Rep. 2016 Jun;4(12). pii: e12846. doi: 10.14814/phy2.12846.

4.

Blocking rpS6 Phosphorylation Exacerbates Tsc1 Deletion-Induced Kidney Growth.

Wu H, Chen J, Xu J, Dong Z, Meyuhas O, Chen JK.

J Am Soc Nephrol. 2016 Apr;27(4):1145-58. doi: 10.1681/ASN.2014121264. Epub 2015 Aug 21.

5.

Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cells.

Xu JX, Lu TS, Li S, Wu Y, Ding L, Denker BM, Bonventre JV, Kong T.

Physiol Genomics. 2015 Feb;47(2):24-32. doi: 10.1152/physiolgenomics.00090.2014. Epub 2014 Dec 9.

6.

Kidney: polycystic kidney disease.

Paul BM, Vanden Heuvel GB.

Wiley Interdiscip Rev Dev Biol. 2014 Nov-Dec;3(6):465-87. doi: 10.1002/wdev.152. Epub 2014 Sep 3. Review.

7.

Inactivation of integrin-β1 prevents the development of polycystic kidney disease after the loss of polycystin-1.

Lee K, Boctor S, Barisoni LM, Gusella GL.

J Am Soc Nephrol. 2015 Apr;26(4):888-95. doi: 10.1681/ASN.2013111179. Epub 2014 Aug 21.

8.

L-type calcium channel modulates cystic kidney phenotype.

Jin X, Muntean BS, Aal-Aaboda MS, Duan Q, Zhou J, Nauli SM.

Biochim Biophys Acta. 2014 Sep;1842(9):1518-26. doi: 10.1016/j.bbadis.2014.06.001. Epub 2014 Jun 9.

9.

Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease.

Harris PC, Torres VE.

J Clin Invest. 2014 Jun;124(6):2315-24. doi: 10.1172/JCI72272. Epub 2014 Jun 2. Review.

10.

Determination of urinary lithogenic parameters in murine models orthologous to autosomal dominant polycystic kidney disease.

Ferraz RR, Fonseca JM, Germino GG, Onuchic LF, Heilberg IP.

Urolithiasis. 2014 Aug;42(4):301-7. doi: 10.1007/s00240-014-0664-1. Epub 2014 May 10.

11.

Polycystic kidney disease - where gene dosage counts.

Eccles MR, Stayner CA.

F1000Prime Rep. 2014 Apr 1;6:24. doi: 10.12703/P6-24. eCollection 2014. Review.

12.

Ciliotherapy: a novel intervention in polycystic kidney disease.

Kathem SH, Mohieldin AM, Abdul-Majeed S, Ismail SH, Altaei QH, Alshimmari IK, Alsaidi MM, Khammas H, Nauli AM, Joe B, Nauli SM.

J Geriatr Cardiol. 2014 Mar;11(1):63-73. doi: 10.3969/j.issn.1671-5411.2014.01.001.

13.

Polycystin-1: a master regulator of intersecting cystic pathways.

Fedeles SV, Gallagher AR, Somlo S.

Trends Mol Med. 2014 May;20(5):251-60. doi: 10.1016/j.molmed.2014.01.004. Epub 2014 Jan 31. Review.

14.

Renal cyst growth is the main determinant for hypertension and concentrating deficit in Pkd1-deficient mice.

Fonseca JM, Bastos AP, Amaral AG, Sousa MF, Souza LE, Malheiros DM, Piontek K, Irigoyen MC, Watnick TJ, Onuchic LF.

Kidney Int. 2014 May;85(5):1137-50. doi: 10.1038/ki.2013.501. Epub 2014 Jan 15.

15.

Acute Kidney Injury due to Crescentic Glomerulonephritis in a Patient with Polycystic Kidney Disease.

Maggard R, Makary R, Monteiro CL, James LR.

Case Rep Nephrol Urol. 2013 Jul 11;3(2):99-104. doi: 10.1159/000353850. Print 2013 Jul.

16.

A telomerase immortalized human proximal tubule cell line with a truncation mutation (Q4004X) in polycystin-1.

Herbert BS, Grimes BR, Xu WM, Werner M, Ward C, Rossetti S, Harris P, Bello-Reuss E, Ward HH, Miller C, Gattone VH 2nd, Phillips CL, Wandinger-Ness A, Bacallao RL.

PLoS One. 2013;8(1):e55191. doi: 10.1371/journal.pone.0055191. Epub 2013 Jan 28.

17.

Chronic asymptomatic pyuria precedes overt urinary tract infection and deterioration of renal function in autosomal dominant polycystic kidney disease.

Hwang JH, Park HC, Jeong JC, Ha Baek S, Han MY, Bang K, Cho JY, Yu SH, Yang J, Oh KH, Hwang YH, Ahn C.

BMC Nephrol. 2013 Jan 7;14:1. doi: 10.1186/1471-2369-14-1.

18.

G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease.

Kwon M, Pavlov TS, Nozu K, Rasmussen SA, Ilatovskaya DV, Lerch-Gaggl A, North LM, Kim H, Qian F, Sweeney WE Jr, Avner ED, Blumer JB, Staruschenko A, Park F.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21462-7. doi: 10.1073/pnas.1216830110. Epub 2012 Dec 10.

19.

Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity.

Hopp K, Ward CJ, Hommerding CJ, Nasr SH, Tuan HF, Gainullin VG, Rossetti S, Torres VE, Harris PC.

J Clin Invest. 2012 Nov;122(11):4257-73. doi: 10.1172/JCI64313. Epub 2012 Oct 15.

20.

The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies.

Pan J, Seeger-Nukpezah T, Golemis EA.

Cell Mol Life Sci. 2013 Jun;70(11):1849-74. doi: 10.1007/s00018-012-1052-z. Epub 2012 Jul 11. Review.

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