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Items: 1 to 20 of 115

1.

Wnt7a Inhibits IL-1β Induced Catabolic Gene Expression and Prevents Articular Cartilage Damage in Experimental Osteoarthritis.

Gibson AL, Hui Mingalone CK, Foote AT, Uchimura T, Zhang M, Zeng L.

Sci Rep. 2017 Feb 6;7:41823. doi: 10.1038/srep41823.

2.

Osteoarthritis: toward a comprehensive understanding of pathological mechanism.

Chen D, Shen J, Zhao W, Wang T, Han L, Hamilton JL, Im HJ.

Bone Res. 2017 Jan 17;5:16044. doi: 10.1038/boneres.2016.44. Review.

3.

Recent developments in emerging therapeutic targets of osteoarthritis.

Sun MM, Beier F, Pest MA.

Curr Opin Rheumatol. 2017 Jan;29(1):96-102.

4.

Sclerostin expression and functions beyond the osteocyte.

Weivoda MM, Youssef SJ, Oursler MJ.

Bone. 2017 Mar;96:45-50. doi: 10.1016/j.bone.2016.11.024.

PMID:
27888056
5.

Endogenous DKK1 and FRZB Regulate Chondrogenesis and Hypertrophy in Three-Dimensional Cultures of Human Chondrocytes and Human Mesenchymal Stem Cells.

Zhong L, Huang X, Rodrigues ED, Leijten JC, Verrips T, El Khattabi M, Karperien M, Post JN.

Stem Cells Dev. 2016 Dec 1;25(23):1808-1817.

6.

Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury.

Embree MC, Chen M, Pylawka S, Kong D, Iwaoka GM, Kalajzic I, Yao H, Shi C, Sun D, Sheu TJ, Koslovsky DA, Koch A, Mao JJ.

Nat Commun. 2016 Oct 10;7:13073. doi: 10.1038/ncomms13073.

7.

A Qualitative Model of the Differentiation Network in Chondrocyte Maturation: A Holistic View of Chondrocyte Hypertrophy.

Kerkhofs J, Leijten J, Bolander J, Luyten FP, Post JN, Geris L.

PLoS One. 2016 Aug 31;11(8):e0162052. doi: 10.1371/journal.pone.0162052.

8.

Molecular hydrogen suppresses activated Wnt/β-catenin signaling.

Lin Y, Ohkawara B, Ito M, Misawa N, Miyamoto K, Takegami Y, Masuda A, Toyokuni S, Ohno K.

Sci Rep. 2016 Aug 25;6:31986. doi: 10.1038/srep31986.

9.

The Expression of Osteopontin and Wnt5a in Articular Cartilage of Patients with Knee Osteoarthritis and Its Correlation with Disease Severity.

Li Y, Xiao W, Sun M, Deng Z, Zeng C, Li H, Yang T, Li L, Luo W, Lei G.

Biomed Res Int. 2016;2016:9561058. doi: 10.1155/2016/9561058.

10.

The inhibition of EZH2 ameliorates osteoarthritis development through the Wnt/β-catenin pathway.

Chen L, Wu Y, Wu Y, Wang Y, Sun L, Li F.

Sci Rep. 2016 Aug 19;6:29176. doi: 10.1038/srep29176.

11.

Runx2 and microRNA regulation in bone and cartilage diseases.

Zhao W, Zhang S, Wang B, Huang J, Lu WW, Chen D.

Ann N Y Acad Sci. 2016 Nov;1383(1):80-87. doi: 10.1111/nyas.13206.

PMID:
27526290
12.

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis.

Nalesso G, Thomas BL, Sherwood JC, Yu J, Addimanda O, Eldridge SE, Thorup AS, Dale L, Schett G, Zwerina J, Eltawil N, Pitzalis C, Dell'Accio F.

Ann Rheum Dis. 2017 Jan;76(1):218-226. doi: 10.1136/annrheumdis-2015-208577.

13.

Interaction of HIF1α and β-catenin inhibits matrix metalloproteinase 13 expression and prevents cartilage damage in mice.

Bouaziz W, Sigaux J, Modrowski D, Devignes CS, Funck-Brentano T, Richette P, Ea HK, Provot S, Cohen-Solal M, Haÿ E.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):5453-8. doi: 10.1073/pnas.1514854113.

14.

Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis.

Rockel JS, Yu C, Whetstone H, Craft AM, Reilly K, Ma H, Tsushima H, Puviindran V, Al-Jazrawe M, Keller GM, Alman BA.

J Clin Invest. 2016 May 2;126(5):1649-63. doi: 10.1172/JCI80205.

15.

Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6.

Schumacher CA, Joiner DM, Less KD, Drewry MO, Williams BO.

Bone Res. 2016 Mar 1;4:15042. doi: 10.1038/boneres.2015.42.

16.

Current research on pharmacologic and regenerative therapies for osteoarthritis.

Zhang W, Ouyang H, Dass CR, Xu J.

Bone Res. 2016 Mar 1;4:15040. doi: 10.1038/boneres.2015.40. Review.

17.

Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage.

Zhang M, Lu Q, Miller AH, Barnthouse NC, Wang J.

Int J Biochem Cell Biol. 2016 Mar;72:125-34. doi: 10.1016/j.biocel.2016.01.013.

18.
19.

Sclerostin Immunoreactivity Increases in Cortical Bone Osteocytes and Decreases in Articular Cartilage Chondrocytes in Aging Mice.

Thompson ML, Jimenez-Andrade JM, Mantyh PW.

J Histochem Cytochem. 2016 Mar;64(3):179-89. doi: 10.1369/0022155415626499.

20.

Dickkopf-3 is upregulated in osteoarthritis and has a chondroprotective role.

Snelling SJ, Davidson RK, Swingler TE, Le LT, Barter MJ, Culley KL, Price A, Carr AJ, Clark IM.

Osteoarthritis Cartilage. 2016 May;24(5):883-91. doi: 10.1016/j.joca.2015.11.021.

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