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Items: 1 to 20 of 131


Selective Surface PEGylation of UiO-66 Nanoparticles for Enhanced Stability, Cell Uptake, and pH-Responsive Drug Delivery.

Abánades Lázaro I, Haddad S, Sacca S, Orellana-Tavra C, Fairen-Jimenez D, Forgan RS.

Chem. 2017 Apr 13;2(4):561-578. doi: 10.1016/j.chempr.2017.02.005.


Teaching the basics of cancer metabolism: Developing antitumor strategies by exploiting the differences between normal and cancer cell metabolism.

Kalyanaraman B.

Redox Biol. 2017 Aug;12:833-842. doi: 10.1016/j.redox.2017.04.018. Epub 2017 Apr 13. Review.


Metabolic analysis of radioresistant medulloblastoma stem-like clones and potential therapeutic targets.

Sun L, Moritake T, Ito K, Matsumoto Y, Yasui H, Nakagawa H, Hirayama A, Inanami O, Tsuboi K.

PLoS One. 2017 Apr 20;12(4):e0176162. doi: 10.1371/journal.pone.0176162. eCollection 2017.


Oncogenic role of PDK4 in human colon cancer cells.

Leclerc D, Pham DN, Lévesque N, Truongcao M, Foulkes WD, Sapienza C, Rozen R.

Br J Cancer. 2017 Mar 28;116(7):930-936. doi: 10.1038/bjc.2017.38. Epub 2017 Feb 16.


pH, Lactate, and Hypoxia: Reciprocity in Regulating High-Affinity Monocarboxylate Transporter Expression in Glioblastoma.

Caruso JP, Koch BJ, Benson PD, Varughese E, Monterey MD, Lee AE, Dave AM, Kiousis S, Sloan AE, Mathupala SP.

Neoplasia. 2017 Feb;19(2):121-134. doi: 10.1016/j.neo.2016.12.011. Epub 2017 Jan 13.


Crosstalk among proteome, acetylome and succinylome in colon cancer HCT116 cell treated with sodium dichloroacetate.

Zhu D, Hou L, Hu B, Zhao H, Sun J, Wang J, Meng X.

Sci Rep. 2016 Nov 22;6:37478. doi: 10.1038/srep37478.


Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1.

James MO, Jahn SC, Zhong G, Smeltz MG, Hu Z, Stacpoole PW.

Pharmacol Ther. 2017 Feb;170:166-180. doi: 10.1016/j.pharmthera.2016.10.018. Epub 2016 Oct 19. Review.


TP53 mutation hits energy metabolism and increases glycolysis in breast cancer.

Harami-Papp H, Pongor LS, Munkácsy G, Horváth G, Nagy ÁM, Ambrus A, Hauser P, Szabó A, Tretter L, Győrffy B.

Oncotarget. 2016 Oct 11;7(41):67183-67195. doi: 10.18632/oncotarget.11594.


Pyruvate dehydrogenase kinase regulates hepatitis C virus replication.

Jung GS, Jeon JH, Choi YK, Jang SY, Park SY, Kim SW, Byun JK, Kim MK, Lee S, Shin EC, Lee IK, Kang YN, Park KG.

Sci Rep. 2016 Jul 29;6:30846. doi: 10.1038/srep30846.


Dichloroacetate and metformin synergistically suppress the growth of ovarian cancer cells.

Li B, Li X, Ni Z, Zhang Y, Zeng Y, Yan X, Huang Y, He J, Lyu X, Wu Y, Wang Y, Zheng Y, He F.

Oncotarget. 2016 Sep 13;7(37):59458-59470. doi: 10.18632/oncotarget.10694.


Targeting Cancer Metabolism - Revisiting the Warburg Effects.

Tran Q, Lee H, Park J, Kim SH, Park J.

Toxicol Res. 2016 Jul;32(3):177-93. doi: 10.5487/TR.2016.32.3.177. Epub 2016 Jul 30. Review.


Transforming Growth Factor β Mediates Drug Resistance by Regulating the Expression of Pyruvate Dehydrogenase Kinase 4 in Colorectal Cancer.

Zhang Y, Zhang Y, Geng L, Yi H, Huo W, Talmon G, Kim YC, Wang SM, Wang J.

J Biol Chem. 2016 Aug 12;291(33):17405-16. doi: 10.1074/jbc.M116.713735. Epub 2016 Jun 21.


Pro-haloacetate Nanoparticles for Efficient Cancer Therapy via Pyruvate Dehydrogenase Kinase Modulation.

Misra SK, Ye M, Ostadhossein F, Pan D.

Sci Rep. 2016 Jun 21;6:28196. doi: 10.1038/srep28196.


Metabolic rewiring in melanoma.

Ratnikov BI, Scott DA, Osterman AL, Smith JW, Ronai ZA.

Oncogene. 2017 Jan 12;36(2):147-157. doi: 10.1038/onc.2016.198. Epub 2016 Jun 6. Review.


Mitochondrial dysfunction-mediated apoptosis resistance associates with defective heat shock protein response in African-American men with prostate cancer.

Chaudhary AK, Bhat TA, Kumar S, Kumar A, Kumar R, Underwood W, Koochekpour S, Shourideh M, Yadav N, Dhar S, Chandra D.

Br J Cancer. 2016 May 10;114(10):1090-100. doi: 10.1038/bjc.2016.88. Epub 2016 Apr 26.


Inhibition of mitochondrial 2-oxoglutarate dehydrogenase impairs viability of cancer cells in a cell-specific metabolism-dependent manner.

Bunik VI, Mkrtchyan G, Grabarska A, Oppermann H, Daloso D, Araujo WL, Juszczak M, Rzeski W, Bettendorff L, Fernie AR, Meixensberger J, Stepulak A, Gaunitz F.

Oncotarget. 2016 May 3;7(18):26400-21. doi: 10.18632/oncotarget.8387.


Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1.

Voltan R, Rimondi E, Melloni E, Gilli P, Bertolasi V, Casciano F, Rigolin GM, Zauli G, Secchiero P.

Oncotarget. 2016 Apr 5;7(14):18965-77. doi: 10.18632/oncotarget.7879.


Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.

Davidson SM, Papagiannakopoulos T, Olenchock BA, Heyman JE, Keibler MA, Luengo A, Bauer MR, Jha AK, O'Brien JP, Pierce KA, Gui DY, Sullivan LB, Wasylenko TM, Subbaraj L, Chin CR, Stephanopolous G, Mott BT, Jacks T, Clish CB, Vander Heiden MG.

Cell Metab. 2016 Mar 8;23(3):517-28. doi: 10.1016/j.cmet.2016.01.007. Epub 2016 Feb 4.


Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia (AML) cell growth.

Qin L, Tian Y, Yu Z, Shi D, Wang J, Zhang C, Peng R, Chen X, Liu C, Chen Y, Huang W, Deng W.

Oncotarget. 2016 Jan 12;7(2):1395-407. doi: 10.18632/oncotarget.6366.

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