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Items: 17


Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca2+ signalling.

Stadler S, Nguyen CH, Schachner H, Milovanovic D, Holzner S, Brenner S, Eichsteininger J, Stadler M, Senfter D, Krenn L, Schmidt WM, Huttary N, Krieger S, Koperek O, Bago-Horvath Z, Brendel KA, Marian B, de Wever O, Mader RM, Giessrigl B, Jäger W, Dolznig H, Krupitza G.

Cell Mol Life Sci. 2017 May;74(10):1907-1921. doi: 10.1007/s00018-016-2441-5. Epub 2016 Dec 24.


Phospholipase Cε Modulates Rap1 Activity and the Endothelial Barrier.

DiStefano PV, Smrcka AV, Glading AJ.

PLoS One. 2016 Sep 9;11(9):e0162338. doi: 10.1371/journal.pone.0162338. eCollection 2016.


Structure, functional regulation and signaling properties of Rap2B.

Qu D, Huang H, DI J, Gao K, Lu Z, Zheng J.

Oncol Lett. 2016 Apr;11(4):2339-2346. Epub 2016 Feb 23.


Cyclin A2: At the crossroads of cell cycle and cell invasion.

Loukil A, Cheung CT, Bendris N, Lemmers B, Peter M, Blanchard JM.

World J Biol Chem. 2015 Nov 26;6(4):346-50. doi: 10.4331/wjbc.v6.i4.346. Review.


Thrombin promotes sustained signaling and inflammatory gene expression through the CDC25 and Ras-associating domains of phospholipase Cϵ.

Dusaban SS, Kunkel MT, Smrcka AV, Brown JH.

J Biol Chem. 2015 Oct 30;290(44):26776-83. doi: 10.1074/jbc.M115.676098. Epub 2015 Sep 8.


Phospholipase Cδ1 induces E-cadherin expression and suppresses malignancy in colorectal cancer cells.

Satow R, Hirano T, Batori R, Nakamura T, Murayama Y, Fukami K.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13505-10. doi: 10.1073/pnas.1405374111. Epub 2014 Sep 2.


Filamin and Phospholipase C-ε are required for calcium signaling in the Caenorhabditis elegans Spermatheca.

Kovacevic I, Cram EJ.

Worm. 2013 Jul 1;2(3):e25717. doi: 10.4161/worm.25717. Epub 2013 Jul 12.


Phosphoinositides: tiny lipids with giant impact on cell regulation.

Balla T.

Physiol Rev. 2013 Jul;93(3):1019-137. doi: 10.1152/physrev.00028.2012. Review.


Filamin and phospholipase C-ε are required for calcium signaling in the Caenorhabditis elegans spermatheca.

Kovacevic I, Orozco JM, Cram EJ.

PLoS Genet. 2013 May;9(5):e1003510. doi: 10.1371/journal.pgen.1003510. Epub 2013 May 9.


Expression of Phosphoinositide-specific phospholipase C enzymes in human osteosarcoma cell lines.

Lo Vasco VR, Leopizzi M, Chiappetta C, Puggioni C, Di Cristofano C, Della Rocca C.

J Cell Commun Signal. 2013 Jun;7(2):141-50. doi: 10.1007/s12079-013-0194-6. Epub 2013 Feb 22.


Phospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses.

Dusaban SS, Purcell NH, Rockenstein E, Masliah E, Cho MK, Smrcka AV, Brown JH.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3609-14. doi: 10.1073/pnas.1217355110. Epub 2013 Feb 11.


Fluorescent phosphatidylinositol 4,5-bisphosphate derivatives with modified 6-hydroxy group as novel substrates for phospholipase C.

Wang X, Barrett M, Sondek J, Harden TK, Zhang Q.

Biochemistry. 2012 Jul 3;51(26):5300-6. Epub 2012 Jun 22.


Chemokines and the signaling modules regulating integrin affinity.

Montresor A, Toffali L, Constantin G, Laudanna C.

Front Immunol. 2012 May 25;3:127. doi: 10.3389/fimmu.2012.00127. eCollection 2012.


The phospholipase C isozymes and their regulation.

Gresset A, Sondek J, Harden TK.

Subcell Biochem. 2012;58:61-94. doi: 10.1007/978-94-007-3012-0_3. Review.


Mechanism of activation and inactivation of Gq/phospholipase C-β signaling nodes.

Harden TK, Waldo GL, Hicks SN, Sondek J.

Chem Rev. 2011 Oct 12;111(10):6120-9. doi: 10.1021/cr200209p. No abstract available.


Inhibition of MLC phosphorylation restricts replication of influenza virus--a mechanism of action for anti-influenza agents.

Haidari M, Zhang W, Ganjehei L, Ali M, Chen Z.

PLoS One. 2011;6(6):e21444. doi: 10.1371/journal.pone.0021444. Epub 2011 Jun 23.


Phospholipase C isozymes as effectors of Ras superfamily GTPases.

Harden TK, Hicks SN, Sondek J.

J Lipid Res. 2009 Apr;50 Suppl:S243-8. doi: 10.1194/jlr.R800045-JLR200. Epub 2008 Nov 24.

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