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Items: 20

1.

Right ventricular nitric oxide signaling in an ovine model of congenital heart disease: a preserved fetal phenotype.

Kameny RJ, He Y, Morris C, Sun C, Johengen M, Gong W, Raff GW, Datar SA, Oishi PE, Fineman JR.

Am J Physiol Heart Circ Physiol. 2015 Jul 1;309(1):H157-65. doi: 10.1152/ajpheart.00103.2015. Epub 2015 May 1.

2.

Protein engineering to develop a redox insensitive endothelial nitric oxide synthase.

Rafikov R, Kumar S, Aggarwal S, Pardo D, Fonseca FV, Ransom J, Rafikova O, Chen Q, Springer ML, Black SM.

Redox Biol. 2014;2:156-64. doi: 10.1016/j.redox.2013.12.015. Epub 2014 Jan 14.

3.

Nitrosation-dependent caveolin 1 phosphorylation, ubiquitination, and degradation and its association with idiopathic pulmonary arterial hypertension.

Bakhshi FR, Mao M, Shajahan AN, Piegeler T, Chen Z, Chernaya O, Sharma T, Elliott WM, Szulcek R, Bogaard HJ, Comhair S, Erzurum S, van Nieuw Amerongen GP, Bonini MG, Minshall RD.

Pulm Circ. 2013 Dec;3(4):816-30. doi: 10.1086/674753.

4.

Altered reactivity and nitric oxide signaling in the isolated thoracic duct from an ovine model of congenital heart disease with increased pulmonary blood flow.

Datar SA, Oishi PE, Gong W, Bennett SH, Sun CE, Johengen M, Maki J, Johnson RC, Raff GW, Fineman JR.

Am J Physiol Heart Circ Physiol. 2014 Apr 1;306(7):H954-62. doi: 10.1152/ajpheart.00841.2013. Epub 2014 Feb 14.

5.

L-carnitine preserves endothelial function in a lamb model of increased pulmonary blood flow.

Sharma S, Aramburo A, Rafikov R, Sun X, Kumar S, Oishi PE, Datar SA, Raff G, Xoinis K, Kalkan G, Fratz S, Fineman JR, Black SM.

Pediatr Res. 2013 Jul;74(1):39-47. doi: 10.1038/pr.2013.71. Epub 2013 Apr 29.

6.

Role of carnitine acetyl transferase in regulation of nitric oxide signaling in pulmonary arterial endothelial cells.

Sharma S, Sun X, Agarwal S, Rafikov R, Dasarathy S, Kumar S, Black SM.

Int J Mol Sci. 2012 Dec 21;14(1):255-72. doi: 10.3390/ijms14010255.

7.

Chronic inhibition of PPAR-γ signaling induces endothelial dysfunction in the juvenile lamb.

Sharma S, Barton J, Rafikov R, Aggarwal S, Kuo HC, Oishi PE, Datar SA, Fineman JR, Black SM.

Pulm Pharmacol Ther. 2013 Apr;26(2):271-80. doi: 10.1016/j.pupt.2012.12.004. Epub 2012 Dec 17.

8.

Disruption of endothelial cell mitochondrial bioenergetics in lambs with increased pulmonary blood flow.

Sun X, Sharma S, Fratz S, Kumar S, Rafikov R, Aggarwal S, Rafikova O, Lu Q, Burns T, Dasarathy S, Wright J, Schreiber C, Radman M, Fineman JR, Black SM.

Antioxid Redox Signal. 2013 May 10;18(14):1739-52. doi: 10.1089/ars.2012.4806. Epub 2013 Mar 14.

9.

The adventitia: essential regulator of vascular wall structure and function.

Stenmark KR, Yeager ME, El Kasmi KC, Nozik-Grayck E, Gerasimovskaya EV, Li M, Riddle SR, Frid MG.

Annu Rev Physiol. 2013;75:23-47. doi: 10.1146/annurev-physiol-030212-183802. Epub 2012 Dec 3. Review.

10.

Rosiglitazone preserves pulmonary vascular function in lambs with increased pulmonary blood flow.

Oishi PE, Sharma S, Datar SA, Kumar S, Aggarwal S, Lu Q, Raff G, Azakie A, Hsu JH, Sajti E, Fratz S, Black SM, Fineman JR.

Pediatr Res. 2013 Jan;73(1):54-61. doi: 10.1038/pr.2012.149. Epub 2012 Nov 5. Erratum in: Pediatr Res 2013 Dec;74(6):742.

11.

Tezosentan increases nitric oxide signaling via enhanced hydrogen peroxide generation in lambs with surgically induced acute increases in pulmonary blood flow.

Kumar S, Oishi PE, Rafikov R, Aggarwal S, Hou Y, Datar SA, Sharma S, Azakie A, Fineman JR, Black SM.

J Cell Biochem. 2013 Feb;114(2):435-447. doi: 10.1002/jcb.24383.

12.

Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I.

Sharma S, Sun X, Kumar S, Rafikov R, Aramburo A, Kalkan G, Tian J, Rehmani I, Kallarackal S, Fineman JR, Black SM.

Free Radic Biol Med. 2012 Jul 15;53(2):216-29. doi: 10.1016/j.freeradbiomed.2012.03.016. Epub 2012 Apr 16.

13.

Oxidative stress and the development of endothelial dysfunction in congenital heart disease with increased pulmonary blood flow: lessons from the neonatal lamb.

Aggarwal S, Gross C, Fineman JR, Black SM.

Trends Cardiovasc Med. 2010 Oct;20(7):238-46. doi: 10.1016/j.tcm.2011.11.010. Review.

14.

Altered lymphatics in an ovine model of congenital heart disease with increased pulmonary blood flow.

Datar SA, Johnson EG, Oishi PE, Johengen M, Tang E, Aramburo A, Barton J, Kuo HC, Bennett S, Xoinis K, Reel B, Kalkan G, Sajti E, Osorio O, Raff GW, Matthay MA, Fineman JR.

Am J Physiol Lung Cell Mol Physiol. 2012 Mar 15;302(6):L530-40. doi: 10.1152/ajplung.00324.2011. Epub 2011 Dec 29.

15.

Increased p38 mitogen-activated protein kinase signaling is involved in the oxidative stress associated with oxygen and glucose deprivation in neonatal hippocampal slice cultures.

Lu Q, Rau TF, Harris V, Johnson M, Poulsen DJ, Black SM.

Eur J Neurosci. 2011 Oct;34(7):1093-101. doi: 10.1111/j.1460-9568.2011.07786.x. Epub 2011 Sep 21.

16.

Early determinants of pulmonary vascular remodeling in animal models of complex congenital heart disease.

Fratz S, Fineman JR, Görlach A, Sharma S, Oishi P, Schreiber C, Kietzmann T, Adatia I, Hess J, Black SM.

Circulation. 2011 Mar 1;123(8):916-23. doi: 10.1161/CIRCULATIONAHA.110.978528. Review. No abstract available.

17.

Attenuated vasodilatation in lambs with endogenous and exogenous activation of cGMP signaling: role of protein kinase G nitration.

Aggarwal S, Gross CM, Kumar S, Datar S, Oishi P, Kalkan G, Schreiber C, Fratz S, Fineman JR, Black SM.

J Cell Physiol. 2011 Dec;226(12):3104-13. doi: 10.1002/jcp.22692.

18.

Hyperthermia-induced Hsp90·eNOS preserves mitochondrial respiration in hyperglycemic endothelial cells by down-regulating Glut-1 and up-regulating G6PD activity.

Presley T, Vedam K, Druhan LJ, Ilangovan G.

J Biol Chem. 2010 Dec 3;285(49):38194-203. doi: 10.1074/jbc.M110.147728. Epub 2010 Sep 22.

19.

Perinatal changes in superoxide generation in the ovine lung: Alterations associated with increased pulmonary blood flow.

Sharma S, Kumar S, Wiseman DA, Kallarackal S, Ponnala S, Elgaish M, Tian J, Fineman JR, Black SM.

Vascul Pharmacol. 2010 Jul-Aug;53(1-2):38-52. doi: 10.1016/j.vph.2010.03.005. Epub 2010 Mar 31.

20.

Effect of PPARgamma inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension.

Tian J, Smith A, Nechtman J, Podolsky R, Aggarwal S, Snead C, Kumar S, Elgaish M, Oishi P, Göerlach A, Fratz S, Hess J, Catravas JD, Verin AD, Fineman JR, She JX, Black SM.

Physiol Genomics. 2009 Dec 30;40(1):48-60. doi: 10.1152/physiolgenomics.00094.2009. Epub 2009 Oct 13.

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