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Items: 1 to 20 of 56


Single-cell profiling screen identifies microtubule-dependent reduction of variability in signaling.

Pesce CG, Zdraljevic S, Peria WJ, Bush A, Repetto MV, Rockwell D, Yu RC, Colman-Lerner A, Brent R.

Mol Syst Biol. 2018 Apr 4;14(4):e7390. doi: 10.15252/msb.20167390.


Sharing of Phosphatases Promotes Response Plasticity in Phosphorylation Cascades.

Ghosh B, Sarma U, Sourjik V, Legewie S.

Biophys J. 2018 Jan 9;114(1):223-236. doi: 10.1016/j.bpj.2017.10.037.


Heat stress promotes longevity in budding yeast by relaxing the confinement of age-promoting factors in the mother cell.

Baldi S, Bolognesi A, Meinema AC, Barral Y.

Elife. 2017 Dec 28;6. pii: e28329. doi: 10.7554/eLife.28329.


Epigenetic control of pheromone MAPK signaling determines sexual fecundity in Candida albicans.

Scaduto CM, Kabrawala S, Thomson GJ, Scheving W, Ly A, Anderson MZ, Whiteway M, Bennett RJ.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13780-13785. doi: 10.1073/pnas.1711141115. Epub 2017 Dec 18.


Spatial and temporal signal processing and decision making by MAPK pathways.

Atay O, Skotheim JM.

J Cell Biol. 2017 Feb;216(2):317-330. doi: 10.1083/jcb.201609124. Epub 2017 Jan 2. Review.


Robust Synthetic Circuits for Two-Dimensional Control of Gene Expression in Yeast.

Aranda-Díaz A, Mace K, Zuleta I, Harrigan P, El-Samad H.

ACS Synth Biol. 2017 Mar 17;6(3):545-554. doi: 10.1021/acssynbio.6b00251. Epub 2016 Dec 27.


Single-cell dynamics and variability of MAPK activity in a yeast differentiation pathway.

Conlon P, Gelin-Licht R, Ganesan A, Zhang J, Levchenko A.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):E5896-E5905. Epub 2016 Sep 20.


Sensory input attenuation allows predictive sexual response in yeast.

Banderas A, Koltai M, Anders A, Sourjik V.

Nat Commun. 2016 Aug 25;7:12590. doi: 10.1038/ncomms12590.


Switch-like Transitions Insulate Network Motifs to Modularize Biological Networks.

Atay O, Doncic A, Skotheim JM.

Cell Syst. 2016 Aug;3(2):121-132. doi: 10.1016/j.cels.2016.06.010. Epub 2016 Jul 21.


Synthetic mixed-signal computation in living cells.

Rubens JR, Selvaggio G, Lu TK.

Nat Commun. 2016 Jun 3;7:11658. doi: 10.1038/ncomms11658.


Sensing a bud in the yeast morphogenesis checkpoint: a role for Elm1.

Kang H, Tsygankov D, Lew DJ.

Mol Biol Cell. 2016 Jun 1;27(11):1764-75. doi: 10.1091/mbc.E16-01-0014. Epub 2016 Apr 6.


Polarity establishment requires localized activation of Cdc42.

Woods B, Kuo CC, Wu CF, Zyla TR, Lew DJ.

J Cell Biol. 2015 Oct 12;211(1):19-26. doi: 10.1083/jcb.201506108.


Different Mechanisms Confer Gradual Control and Memory at Nutrient- and Stress-Regulated Genes in Yeast.

Rienzo A, Poveda-Huertes D, Aydin S, Buchler NE, Pascual-Ahuir A, Proft M.

Mol Cell Biol. 2015 Nov;35(21):3669-83. doi: 10.1128/MCB.00729-15. Epub 2015 Aug 17.


Signal inhibition by a dynamically regulated pool of monophosphorylated MAPK.

Nagiec MJ, McCarter PC, Kelley JB, Dixit G, Elston TC, Dohlman HG.

Mol Biol Cell. 2015 Sep 15;26(18):3359-71. doi: 10.1091/mbc.E15-01-0037. Epub 2015 Jul 15.


Compartmentalization of a bistable switch enables memory to cross a feedback-driven transition.

Doncic A, Atay O, Valk E, Grande A, Bush A, Vasen G, Colman-Lerner A, Loog M, Skotheim JM.

Cell. 2015 Mar 12;160(6):1182-95. doi: 10.1016/j.cell.2015.02.032.


MAPK feedback encodes a switch and timer for tunable stress adaptation in yeast.

English JG, Shellhammer JP, Malahe M, McCarter PC, Elston TC, Dohlman HG.

Sci Signal. 2015 Jan 13;8(359):ra5. doi: 10.1126/scisignal.2005774.


How MAP kinase modules function as robust, yet adaptable, circuits.

Tian T, Harding A.

Cell Cycle. 2014;13(15):2379-90. doi: 10.4161/cc.29349.


Cdc42p-interacting protein Bem4p regulates the filamentous-growth mitogen-activated protein kinase pathway.

Pitoniak A, Chavel CA, Chow J, Smith J, Camara D, Karunanithi S, Li B, Wolfe KH, Cullen PJ.

Mol Cell Biol. 2015 Jan;35(2):417-36. doi: 10.1128/MCB.00850-14. Epub 2014 Nov 10.


Plasma membrane aminoglycerolipid flippase function is required for signaling competence in the yeast mating pheromone response pathway.

Sartorel E, Barrey E, Lau RK, Thorner J.

Mol Biol Cell. 2015 Jan 1;26(1):134-50. doi: 10.1091/mbc.E14-07-1193. Epub 2014 Nov 5.


Inhibitory GEF phosphorylation provides negative feedback in the yeast polarity circuit.

Kuo CC, Savage NS, Chen H, Wu CF, Zyla TR, Lew DJ.

Curr Biol. 2014 Mar 31;24(7):753-9. doi: 10.1016/j.cub.2014.02.024. Epub 2014 Mar 13.

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