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Items: 1 to 20 of 65

1.

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.

Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A.

Dev Cell. 2017 Feb 27;40(4):331-341.e4. doi: 10.1016/j.devcel.2017.01.015.

2.

Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures.

Graham NA, Minasyan A, Lomova A, Cass A, Balanis NG, Friedman M, Chan S, Zhao S, Delgado A, Go J, Beck L, Hurtz C, Ng C, Qiao R, Ten Hoeve J, Palaskas N, Wu H, Müschen M, Multani AS, Port E, Larson SM, Schultz N, Braas D, Christofk HR, Mellinghoff IK, Graeber TG.

Mol Syst Biol. 2017 Feb 15;13(2):914. doi: 10.15252/msb.20167159.

3.

Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation.

Bulusu V, Tumanov S, Michalopoulou E, van den Broek NJ, MacKay G, Nixon C, Dhayade S, Schug ZT, Vande Voorde J, Blyth K, Gottlieb E, Vazquez A, Kamphorst JJ.

Cell Rep. 2017 Jan 17;18(3):647-658. doi: 10.1016/j.celrep.2016.12.055.

4.
5.

Systems-level analysis of mechanisms regulating yeast metabolic flux.

Hackett SR, Zanotelli VR, Xu W, Goya J, Park JO, Perlman DH, Gibney PA, Botstein D, Storey JD, Rabinowitz JD.

Science. 2016 Oct 28;354(6311). pii: aaf2786. Epub 2016 Oct 27.

6.

Understanding metabolism with flux analysis: From theory to application.

Dai Z, Locasale JW.

Metab Eng. 2017 Sep;43(Pt B):94-102. doi: 10.1016/j.ymben.2016.09.005. Epub 2016 Sep 22. Review.

PMID:
27667771
7.

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.

Mayers JR, Torrence ME, Danai LV, Papagiannakopoulos T, Davidson SM, Bauer MR, Lau AN, Ji BW, Dixit PD, Hosios AM, Muir A, Chin CR, Freinkman E, Jacks T, Wolpin BM, Vitkup D, Vander Heiden MG.

Science. 2016 Sep 9;353(6304):1161-5. doi: 10.1126/science.aaf5171.

8.

A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria.

Murima P, Zimmermann M, Chopra T, Pojer F, Fonti G, Dal Peraro M, Alonso S, Sauer U, Pethe K, McKinney JD.

Nat Commun. 2016 Aug 24;7:12527. doi: 10.1038/ncomms12527.

9.

Applications of NMR spectroscopy to systems biochemistry.

Fan TW, Lane AN.

Prog Nucl Magn Reson Spectrosc. 2016 Feb;92-93:18-53. doi: 10.1016/j.pnmrs.2016.01.005. Epub 2016 Feb 6. Review.

10.

MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4.

Hong CS, Graham NA, Gu W, Espindola Camacho C, Mah V, Maresh EL, Alavi M, Bagryanova L, Krotee PAL, Gardner BK, Behbahan IS, Horvath S, Chia D, Mellinghoff IK, Hurvitz SA, Dubinett SM, Critchlow SE, Kurdistani SK, Goodglick L, Braas D, Graeber TG, Christofk HR.

Cell Rep. 2016 Feb 23;14(7):1590-1601. doi: 10.1016/j.celrep.2016.01.057. Epub 2016 Feb 11.

11.

Estimating Metabolic Fluxes Using a Maximum Network Flexibility Paradigm.

Megchelenbrink W, Rossell S, Huynen MA, Notebaart RA, Marchiori E.

PLoS One. 2015 Oct 12;10(10):e0139665. doi: 10.1371/journal.pone.0139665. eCollection 2015.

12.

Inference and Prediction of Metabolic Network Fluxes.

Nikoloski Z, Perez-Storey R, Sweetlove LJ.

Plant Physiol. 2015 Nov;169(3):1443-55. doi: 10.1104/pp.15.01082. Epub 2015 Sep 21.

13.

Metabolomic profiling of the heart during acute ischemic preconditioning reveals a role for SIRT1 in rapid cardioprotective metabolic adaptation.

Nadtochiy SM, Urciuoli W, Zhang J, Schafer X, Munger J, Brookes PS.

J Mol Cell Cardiol. 2015 Nov;88:64-72. doi: 10.1016/j.yjmcc.2015.09.008. Epub 2015 Sep 24.

14.

Bypasses in intracellular glucose metabolism in iron-limited Pseudomonas putida.

Sasnow SS, Wei H, Aristilde L.

Microbiologyopen. 2016 Feb;5(1):3-20. doi: 10.1002/mbo3.287. Epub 2015 Sep 16.

15.

2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling.

Fu X, Chin RM, Vergnes L, Hwang H, Deng G, Xing Y, Pai MY, Li S, Ta L, Fazlollahi F, Chen C, Prins RM, Teitell MA, Nathanson DA, Lai A, Faull KF, Jiang M, Clarke SG, Cloughesy TF, Graeber TG, Braas D, Christofk HR, Jung ME, Reue K, Huang J.

Cell Metab. 2015 Sep 1;22(3):508-15. doi: 10.1016/j.cmet.2015.06.009. Epub 2015 Jul 16.

16.

Pool size measurements facilitate the determination of fluxes at branching points in non-stationary metabolic flux analysis: the case of Arabidopsis thaliana.

Heise R, Fernie AR, Stitt M, Nikoloski Z.

Front Plant Sci. 2015 Jun 2;6:386. doi: 10.3389/fpls.2015.00386. eCollection 2015.

17.

Quantification of folate metabolism using transient metabolic flux analysis.

Tedeschi PM, Johnson-Farley N, Lin H, Shelton LM, Ooga T, Mackay G, Van Den Broek N, Bertino JR, Vazquez A.

Cancer Metab. 2015 May 28;3:6. doi: 10.1186/s40170-015-0132-6. eCollection 2015.

18.

Defining the metabolome: size, flux, and regulation.

Zamboni N, Saghatelian A, Patti GJ.

Mol Cell. 2015 May 21;58(4):699-706. doi: 10.1016/j.molcel.2015.04.021. Review.

19.

Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function.

Burke SJ, May AL, Noland RC, Lu D, Brissova M, Powers AC, Sherrill EM, Karlstad MD, Campagna SR, Stephens JM, Collier JJ.

J Biol Chem. 2015 May 22;290(21):13401-16. doi: 10.1074/jbc.M114.632190. Epub 2015 Apr 7.

20.

Quantifying protein synthesis and degradation in Arabidopsis by dynamic 13CO2 labeling and analysis of enrichment in individual amino acids in their free pools and in protein.

Ishihara H, Obata T, Sulpice R, Fernie AR, Stitt M.

Plant Physiol. 2015 May;168(1):74-93. doi: 10.1104/pp.15.00209. Epub 2015 Mar 25. Erratum in: Plant Physiol. 2015 Jul;168(3):1179.

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