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Items: 1 to 20 of 183

1.

Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.

Coni S, Mancuso AB, Di Magno L, Sdruscia G, Manni S, Serrao SM, Rotili D, Spiombi E, Bufalieri F, Petroni M, Kusio-Kobialka M, De Smaele E, Ferretti E, Capalbo C, Mai A, Niewiadomski P, Screpanti I, Di Marcotullio L, Canettieri G.

Sci Rep. 2017 Mar 9;7:44079. doi: 10.1038/srep44079.

2.

Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis.

Xu T, Zhang H, Park SS, Venneti S, Kuick R, Ha K, Michael LE, Santi M, Uchida C, Uchida T, Srinivasan A, Olson JM, Dlugosz AA, Camelo-Piragua S, Rual JF.

Neoplasia. 2017 Mar;19(3):216-225. doi: 10.1016/j.neo.2017.01.002. Epub 2017 Feb 3.

3.

Epigenetics in cancer stem cells.

Toh TB, Lim JJ, Chow EK.

Mol Cancer. 2017 Feb 1;16(1):29. doi: 10.1186/s12943-017-0596-9. Review.

4.

Suppression of Medulloblastoma Lesions by Forced Migration of Preneoplastic Precursor Cells with Intracerebellar Administration of the Chemokine Cxcl3.

Ceccarelli M, Micheli L, Tirone F.

Front Pharmacol. 2016 Dec 16;7:484. doi: 10.3389/fphar.2016.00484. eCollection 2016.

5.

Know your neighbors: Different tumor microenvironments have implications in immunotherapeutic targeting strategies across MB subgroups.

Pham CD, Mitchell DA.

Oncoimmunology. 2016 Feb 18;5(11):e1144002. doi: 10.1080/2162402X.2016.1144002. eCollection 2016.

6.

Functional Genomics Identifies Tis21-Dependent Mechanisms and Putative Cancer Drug Targets Underlying Medulloblastoma Shh-Type Development.

Gentile G, Ceccarelli M, Micheli L, Tirone F, Cavallaro S.

Front Pharmacol. 2016 Nov 30;7:449. eCollection 2016.

7.

Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype.

Infante P, Alfonsi R, Ingallina C, Quaglio D, Ghirga F, D'Acquarica I, Bernardi F, Di Magno L, Canettieri G, Screpanti I, Gulino A, Botta B, Mori M, Di Marcotullio L.

Cell Death Dis. 2016 Sep 22;7(9):e2376. doi: 10.1038/cddis.2016.195.

8.

PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation.

Zhu G, Rankin SL, Larson JD, Zhu X, Chow LM, Qu C, Zhang J, Ellison DW, Baker SJ.

Cancer Res. 2017 Jan 1;77(1):123-133. doi: 10.1158/0008-5472.CAN-16-1991. Epub 2016 Nov 4.

PMID:
27815386
9.

ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.

Lang PY, Nanjangud GJ, Sokolsky-Papkov M, Shaw C, Hwang D, Parker JS, Kabanov AV, Gershon TR.

Development. 2016 Nov 1;143(21):4038-4052.

PMID:
27803059
10.

In vitro models of cancer stem cells and clinical applications.

S Franco S, Szczesna K, Iliou MS, Al-Qahtani M, Mobasheri A, Kobolák J, Dinnyés A.

BMC Cancer. 2016 Sep 30;16(Suppl 2):738. Review.

11.

Hedgehog Controls Quiescence and Activation of Neural Stem Cells in the Adult Ventricular-Subventricular Zone.

Daynac M, Tirou L, Faure H, Mouthon MA, Gauthier LR, Hahn H, Boussin FD, Ruat M.

Stem Cell Reports. 2016 Oct 11;7(4):735-748. doi: 10.1016/j.stemcr.2016.08.016. Epub 2016 Sep 22.

12.
13.

Stox1 as a novel transcriptional suppressor of Math1 during cerebellar granule neurogenesis and medulloblastoma formation.

Zhang C, Ji Z, Wang M, Zhang W, Yang R, An H, Yang R, van Abel D, van Dijk M, Yang X, Ou G, Zhu HH, Gao WQ.

Cell Death Differ. 2016 Dec;23(12):2042-2053. doi: 10.1038/cdd.2016.85. Epub 2016 Aug 26.

PMID:
27564589
14.

Adult medulloblastoma: A rare case report and literature review.

Faried A, Pribadi MA, Sumargo S, Arifin MZ, Hernowo BS.

Surg Neurol Int. 2016 Jul 7;7(Suppl 17):S481-4. doi: 10.4103/2152-7806.185782. eCollection 2016.

15.

Nestin Mediates Hedgehog Pathway Tumorigenesis.

Li P, Lee EH, Du F, Gordon RE, Yuelling LW, Liu Y, Ng JM, Zhang H, Wu J, Korshunov A, Pfister SM, Curran T, Yang ZJ.

Cancer Res. 2016 Sep 15;76(18):5573-83. doi: 10.1158/0008-5472.CAN-16-1547. Epub 2016 Aug 5.

PMID:
27496710
16.

Defining the clonal dynamics leading to mouse skin tumour initiation.

Sánchez-Danés A, Hannezo E, Larsimont JC, Liagre M, Youssef KK, Simons BD, Blanpain C.

Nature. 2016 Aug 18;536(7616):298-303.

17.

BarTeL, a Genetically Versatile, Bioluminescent and Granule Neuron Precursor-Targeted Mouse Model for Medulloblastoma.

Shackleford GM, Shi XH, Swanson KS, Mahdi MY, Gonzalez-Gomez I, Asgharzadeh S, D'Apuzzo M, Erdreich-Epstein A, Moats RA.

PLoS One. 2016 Jun 16;11(6):e0156907. doi: 10.1371/journal.pone.0156907. eCollection 2016.

18.

Evasion of cell senescence in SHH medulloblastoma.

Tamayo-Orrego L, Swikert SM, Charron F.

Cell Cycle. 2016 Aug 17;15(16):2102-2107. Epub 2016 May 26.

19.

Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition.

Singh S, Howell D, Trivedi N, Kessler K, Ong T, Rosmaninho P, Raposo AA, Robinson G, Roussel MF, Castro DS, Solecki DJ.

Elife. 2016 May 14;5. pii: e12717. doi: 10.7554/eLife.12717.

20.

Medulloblastoma stem cells: Promising targets in medulloblastoma therapy.

Huang GH, Xu QF, Cui YH, Li N, Bian XW, Lv SQ.

Cancer Sci. 2016 May;107(5):583-9. doi: 10.1111/cas.12925. Epub 2016 Apr 27. Review.

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