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CDK1 phosphorylates WRN at collapsed replication forks.

Palermo V, Rinalducci S, Sanchez M, Grillini F, Sommers JA, Brosh RM Jr, Zolla L, Franchitto A, Pichierri P.

Nat Commun. 2016 Sep 16;7:12880. doi: 10.1038/ncomms12880.


Immunogenomic engineering of a plug-and-(dis)play hybridoma platform.

Pogson M, Parola C, Kelton WJ, Heuberger P, Reddy ST.

Nat Commun. 2016 Aug 17;7:12535. doi: 10.1038/ncomms12535.


Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit.

de Araujo PR, Gorthi A, da Silva AE, Tonapi SS, Vo DT, Burns SC, Qiao M, Uren PJ, Yuan ZM, Bishop AJ, Penalva LO.

Am J Pathol. 2016 Sep;186(9):2271-8. doi: 10.1016/j.ajpath.2016.05.020.


Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation.

Mladenova V, Mladenov E, Iliakis G.

Front Oncol. 2016 Jun 28;6:163. doi: 10.3389/fonc.2016.00163. Review.


Current Evidence for Developmental, Structural, and Functional Brain Defects following Prenatal Radiation Exposure.

Verreet T, Verslegers M, Quintens R, Baatout S, Benotmane MA.

Neural Plast. 2016;2016:1243527. doi: 10.1155/2016/1243527. Review.


Non-homologous end joining repair in Xenopus egg extract.

Zhu S, Peng A.

Sci Rep. 2016 Jun 21;6:27797. doi: 10.1038/srep27797.


Low Genetic Quality Alters Key Dimensions of the Mutational Spectrum.

Sharp NP, Agrawal AF.

PLoS Biol. 2016 Mar 25;14(3):e1002419. doi: 10.1371/journal.pbio.1002419.


Enrichment of G2/M cell cycle phase in human pluripotent stem cells enhances HDR-mediated gene repair with customizable endonucleases.

Yang D, Scavuzzo MA, Chmielowiec J, Sharp R, Bajic A, Borowiak M.

Sci Rep. 2016 Feb 18;6:21264. doi: 10.1038/srep21264.


Knock-in of large reporter genes in human cells via CRISPR/Cas9-induced homology-dependent and independent DNA repair.

He X, Tan C, Wang F, Wang Y, Zhou R, Cui D, You W, Zhao H, Ren J, Feng B.

Nucleic Acids Res. 2016 May 19;44(9):e85. doi: 10.1093/nar/gkw064.


Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms.

Kostyrko K, Mermod N.

Nucleic Acids Res. 2016 Apr 7;44(6):e56. doi: 10.1093/nar/gkv1349.


DNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of Cancer.

Velic D, Couturier AM, Ferreira MT, Rodrigue A, Poirier GG, Fleury F, Masson JY.

Biomolecules. 2015 Nov 20;5(4):3204-59. doi: 10.3390/biom5043204. Review.


Use of the HPRT gene to study nuclease-induced DNA double-strand break repair.

Gravells P, Ahrabi S, Vangala RK, Tomita K, Brash JT, Brustle LA, Chung C, Hong JM, Kaloudi A, Humphrey TC, Porter AC.

Hum Mol Genet. 2015 Dec 15;24(24):7097-110. doi: 10.1093/hmg/ddv409.


Circadian molecular clock in lung pathophysiology.

Sundar IK, Yao H, Sellix MT, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2015 Nov 15;309(10):L1056-75. doi: 10.1152/ajplung.00152.2015. Review.


Activation of homologous recombination DNA repair in human skin fibroblasts continuously exposed to X-ray radiation.

Osipov AN, Grekhova A, Pustovalova M, Ozerov IV, Eremin P, Vorobyeva N, Lazareva N, Pulin A, Zhavoronkov A, Roumiantsev S, Klokov D, Eremin I.

Oncotarget. 2015 Sep 29;6(29):26876-85. doi: 10.18632/oncotarget.4946.


Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining.

Beckta JM, Dever SM, Gnawali N, Khalil A, Sule A, Golding SE, Rosenberg E, Narayanan A, Kehn-Hall K, Xu B, Povirk LF, Valerie K.

Oncotarget. 2015 Sep 29;6(29):27674-87. doi: 10.18632/oncotarget.4876.


Interplay between Ku and Replication Protein A in the Restriction of Exo1-mediated DNA Break End Resection.

Krasner DS, Daley JM, Sung P, Niu H.

J Biol Chem. 2015 Jul 24;290(30):18806-16. doi: 10.1074/jbc.M115.660191.


DNA-PKcs plays role in cancer metastasis through regulation of secreted proteins involved in migration and invasion.

Kotula E, Berthault N, Agrario C, Lienafa MC, Simon A, Dingli F, Loew D, Sibut V, Saule S, Dutreix M.

Cell Cycle. 2015;14(12):1961-72. doi: 10.1080/15384101.2015.1026522.


Deregulation of DNA double-strand break repair in multiple myeloma: implications for genome stability.

Herrero AB, San Miguel J, Gutierrez NC.

PLoS One. 2015 Mar 19;10(3):e0121581. doi: 10.1371/journal.pone.0121581.


RAD6 promotes homologous recombination repair by activating the autophagy-mediated degradation of heterochromatin protein HP1.

Chen S, Wang C, Sun L, Wang DL, Chen L, Huang Z, Yang Q, Gao J, Yang XB, Chang JF, Chen P, Lan L, Mao Z, Sun FL.

Mol Cell Biol. 2015 Jan;35(2):406-16. doi: 10.1128/MCB.01044-14.


Intron evolution in Neurospora: the role of mutational bias and selection.

Sun Y, Whittle CA, Corcoran P, Johannesson H.

Genome Res. 2015 Jan;25(1):100-10. doi: 10.1101/gr.175653.114.

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