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Items: 1 to 20 of 41

1.

Engineering extrinsic disorder to control protein activity in living cells.

Dagliyan O, Tarnawski M, Chu PH, Shirvanyants D, Schlichting I, Dokholyan NV, Hahn KM.

Science. 2016 Dec 16;354(6318):1441-1444.

2.

LOVTRAP: A Versatile Method to Control Protein Function with Light.

Wang H, Hahn KM.

Curr Protoc Cell Biol. 2016 Dec 1;73:21.10.1-21.10.14. doi: 10.1002/cpcb.12.

3.

Optogenetic Immunomodulation: Shedding Light on Antitumor Immunity.

Tan P, He L, Han G, Zhou Y.

Trends Biotechnol. 2017 Mar;35(3):215-226. doi: 10.1016/j.tibtech.2016.09.002. Epub 2016 Sep 28. Review.

4.

Targeting protein function: the expanding toolkit for conditional disruption.

Campbell AE, Bennett D.

Biochem J. 2016 Sep 1;473(17):2573-89. doi: 10.1042/BCJ20160240. Review.

5.

Go in! Go out! Inducible control of nuclear localization.

Di Ventura B, Kuhlman B.

Curr Opin Chem Biol. 2016 Oct;34:62-71. doi: 10.1016/j.cbpa.2016.06.009. Epub 2016 Jun 30. Review.

6.

Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation.

He L, Zhang Y, Ma G, Tan P, Li Z, Zang S, Wu X, Jing J, Fang S, Zhou L, Wang Y, Huang Y, Hogan PG, Han G, Zhou Y.

Elife. 2015 Dec 8;4. pii: e10024. doi: 10.7554/eLife.10024.

7.

Light-induced structural changes in a short light, oxygen, voltage (LOV) protein revealed by molecular dynamics simulations-implications for the understanding of LOV photoactivation.

Bocola M, Schwaneberg U, Jaeger KE, Krauss U.

Front Mol Biosci. 2015 Oct 1;2:55. doi: 10.3389/fmolb.2015.00055. eCollection 2015.

8.

Applications of hydrogen deuterium exchange (HDX) for the characterization of conformational dynamics in light-activated photoreceptors.

Lindner R, Heintz U, Winkler A.

Front Mol Biosci. 2015 Jun 23;2:33. doi: 10.3389/fmolb.2015.00033. eCollection 2015. Review.

9.

Photoreceptor engineering.

Ziegler T, Möglich A.

Front Mol Biosci. 2015 Jun 17;2:30. doi: 10.3389/fmolb.2015.00030. eCollection 2015. Review.

10.

Photo-sensitive degron variants for tuning protein stability by light.

Usherenko S, Stibbe H, Muscò M, Essen LO, Kostina EA, Taxis C.

BMC Syst Biol. 2014 Nov 18;8:128. doi: 10.1186/s12918-014-0128-9.

11.

Optogenetic approaches to cell migration and beyond.

Weitzman M, Hahn KM.

Curr Opin Cell Biol. 2014 Oct;30:112-20. doi: 10.1016/j.ceb.2014.08.004. Epub 2014 Sep 15. Review.

12.

Optical control of protein-protein interactions via blue light-induced domain swapping.

Reis JM, Burns DC, Woolley GA.

Biochemistry. 2014 Aug 5;53(30):5008-16. doi: 10.1021/bi500622x. Epub 2014 Jul 16.

13.

Anisotropic energy flow and allosteric ligand binding in albumin.

Li G, Magana D, Dyer RB.

Nat Commun. 2014;5:3100. doi: 10.1038/ncomms4100.

14.

General method for regulating protein stability with light.

Bonger KM, Rakhit R, Payumo AY, Chen JK, Wandless TJ.

ACS Chem Biol. 2014 Jan 17;9(1):111-5. doi: 10.1021/cb400755b. Epub 2013 Nov 8.

15.

NMR paves the way for atomic level descriptions of sparsely populated, transiently formed biomolecular conformers.

Sekhar A, Kay LE.

Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):12867-74. doi: 10.1073/pnas.1305688110. Epub 2013 Jul 18.

16.

Signaling mechanisms of LOV domains: new insights from molecular dynamics studies.

Freddolino PL, Gardner KH, Schulten K.

Photochem Photobiol Sci. 2013 Jul;12(7):1158-70. doi: 10.1039/c3pp25400c.

17.

Conformational equilibrium of N-myristoylated cAMP-dependent protein kinase A by molecular dynamics simulations.

Cembran A, Masterson LR, McClendon CL, Taylor SS, Gao J, Veglia G.

Biochemistry. 2012 Dec 21;51(51):10186-96. doi: 10.1021/bi301279f. Epub 2012 Dec 12.

18.

Optogenetic control of cell function using engineered photoreceptors.

Pathak GP, Vrana JD, Tucker CL.

Biol Cell. 2013 Feb;105(2):59-72. doi: 10.1111/boc.201200056. Epub 2012 Dec 21. Review.

19.

Designing photoswitchable peptides using the AsLOV2 domain.

Lungu OI, Hallett RA, Choi EJ, Aiken MJ, Hahn KM, Kuhlman B.

Chem Biol. 2012 Apr 20;19(4):507-17. doi: 10.1016/j.chembiol.2012.02.006. Erratum in: Chem Biol. 2012 Jul 27;19(7):926.

20.

The amino-terminal helix modulates light-activated conformational changes in AsLOV2.

Zayner JP, Antoniou C, Sosnick TR.

J Mol Biol. 2012 May 25;419(1-2):61-74. doi: 10.1016/j.jmb.2012.02.037. Epub 2012 Mar 7.

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