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Items: 18

1.

High Resolution UHPLC-MS Metabolomics and Sedative-Anxiolytic Effects of Latua pubiflora: A Mystic Plant used by Mapuche Amerindians.

Sánchez-Montoya EL, Reyes MA, Pardo J, Nuñez-Alarcón J, Ortiz JG, Jorge JC, Bórquez J, Mocan A, Simirgiotis MJ.

Front Pharmacol. 2017 Jul 26;8:494. doi: 10.3389/fphar.2017.00494. eCollection 2017.

2.

Analysis of β-Subunit-dependent GABAA Receptor Modulation and Behavioral Effects of Valerenic Acid Derivatives.

Khom S, Hintersteiner J, Luger D, Haider M, Pototschnig G, Mihovilovic MD, Schwarzer C, Hering S.

J Pharmacol Exp Ther. 2016 Jun;357(3):580-90. doi: 10.1124/jpet.116.232983. Epub 2016 Apr 18.

3.

Reversal of pentylenetetrazole-altered swimming and neural activity-regulated gene expression in zebrafish larvae by valproic acid and valerian extract.

Torres-Hernández BA, Colón LR, Rosa-Falero C, Torrado A, Miscalichi N, Ortíz JG, González-Sepúlveda L, Pérez-Ríos N, Suárez-Pérez E, Bradsher JN, Behra M.

Psychopharmacology (Berl). 2016 Jul;233(13):2533-47. doi: 10.1007/s00213-016-4304-z. Epub 2016 May 11.

4.

Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site-directed mutagenesis.

Luger D, Poli G, Wieder M, Stadler M, Ke S, Ernst M, Hohaus A, Linder T, Seidel T, Langer T, Khom S, Hering S.

Br J Pharmacol. 2015 Nov;172(22):5403-13. doi: 10.1111/bph.13329. Epub 2015 Oct 25.

5.

Valerenic Acid Protects Against Physical and Psychological Stress by Reducing the Turnover of Serotonin and Norepinephrine in Mouse Hippocampus-Amygdala Region.

Jung HY, Yoo DY, Nam SM, Kim JW, Choi JH, Yoo M, Lee S, Yoon YS, Hwang IK.

J Med Food. 2015 Dec;18(12):1333-9. doi: 10.1089/jmf.2014.3412. Epub 2015 Jul 15.

6.

Valerenic acid and Valeriana officinalis extracts delay onset of Pentylenetetrazole (PTZ)-Induced seizures in adult Danio rerio (Zebrafish).

Torres-Hernández BA, Del Valle-Mojica LM, Ortíz JG.

BMC Complement Altern Med. 2015 Jul 14;15:228. doi: 10.1186/s12906-015-0731-3.

7.

The anxiolytic effects of a Valerian extract is based on valerenic acid.

Becker A, Felgentreff F, Schröder H, Meier B, Brattström A.

BMC Complement Altern Med. 2014 Jul 28;14:267. doi: 10.1186/1472-6882-14-267.

8.

Esters of valerenic acid as potential prodrugs.

Hintersteiner J, Haider M, Luger D, Schwarzer C, Reznicek G, Jäger W, Khom S, Mihovilovic MD, Hering S.

Eur J Pharmacol. 2014 Jul 15;735:123-31. doi: 10.1016/j.ejphar.2014.03.019. Epub 2014 Mar 27.

9.

A case of hyponatremia due to self-treatment of anxiety with a beverage containing valerian root.

Takeshita S, Takeshita J.

Prim Care Companion CNS Disord. 2013;15(1). pii: PCC.12l01482. doi: 10.4088/PCC.12l01482. No abstract available.

10.

GABAA receptor modulation by piperine and a non-TRPV1 activating derivative.

Khom S, Strommer B, Schöffmann A, Hintersteiner J, Baburin I, Erker T, Schwarz T, Schwarzer C, Zaugg J, Hamburger M, Hering S.

Biochem Pharmacol. 2013 Jun 15;85(12):1827-36. doi: 10.1016/j.bcp.2013.04.017. Epub 2013 Apr 25.

11.

Cancer-related stress and complementary and alternative medicine: a review.

Chandwani KD, Ryan JL, Peppone LJ, Janelsins MM, Sprod LK, Devine K, Trevino L, Gewandter J, Morrow GR, Mustian KM.

Evid Based Complement Alternat Med. 2012;2012:979213. doi: 10.1155/2012/979213. Epub 2012 Jul 15.

12.

Dietary and botanical anxiolytics.

Alramadhan E, Hanna MS, Hanna MS, Goldstein TA, Avila SM, Weeks BS.

Med Sci Monit. 2012 Apr;18(4):RA40-8. Review.

13.

Herbal extracts and phytochemicals: plant secondary metabolites and the enhancement of human brain function.

Kennedy DO, Wightman EL.

Adv Nutr. 2011 Jan;2(1):32-50. doi: 10.3945/an.110.000117. Epub 2011 Jan 10. Review.

14.

Evaluation of Behavioral and Pharmacological Effects of Hydroalcoholic Extract of Valeriana prionophylla Standl. from Guatemala.

Holzmann I, Cechinel Filho V, Mora TC, Cáceres A, Martínez JV, Cruz SM, de Souza MM.

Evid Based Complement Alternat Med. 2011;2011:312320. doi: 10.1155/2011/312320. Epub 2011 Jun 30.

15.

Selective Interactions of Valeriana officinalis Extracts and Valerenic Acid with [H]Glutamate Binding to Rat Synaptic Membranes.

Del Valle-Mojica LM, Ayala-Marín YM, Ortiz-Sanchez CM, Torres-Hernández BA, Abdalla-Mukhaimer S, Ortiz JG.

Evid Based Complement Alternat Med. 2011;2011:403591. doi: 10.1155/2011/403591. Epub 2011 Apr 26.

16.

Positive GABA(A) receptor modulators from Acorus calamus and structural analysis of (+)-dioxosarcoguaiacol by 1D and 2D NMR and molecular modeling.

Zaugg J, Eickmeier E, Ebrahimi SN, Baburin I, Hering S, Hamburger M.

J Nat Prod. 2011 Jun 24;74(6):1437-43. doi: 10.1021/np200181d. Epub 2011 May 12.

17.

Aqueous and Ethanolic Valeriana officinalis Extracts Change the Binding of Ligands to Glutamate Receptors.

Del Valle-Mojica LM, Cordero-Hernández JM, González-Medina G, Ramos-Vélez I, Berríos-Cartagena N, Torres-Hernández BA, Ortíz JG.

Evid Based Complement Alternat Med. 2011;2011:891819. doi: 10.1155/2011/891819. Epub 2010 Dec 2.

18.

Valerenic acid derivatives as novel subunit-selective GABAA receptor ligands - in vitro and in vivo characterization.

Khom S, Strommer B, Ramharter J, Schwarz T, Schwarzer C, Erker T, Ecker GF, Mulzer J, Hering S.

Br J Pharmacol. 2010 Sep;161(1):65-78. doi: 10.1111/j.1476-5381.2010.00865.x.

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