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Items: 1 to 20 of 217

1.

Idolizing the clearance of Amyloid-β by microglia.

Van Loon NM, Zelcer N.

Ann Transl Med. 2016 Dec;4(24):536. doi: 10.21037/atm.2016.11.63. No abstract available.

PMID:
28149897
2.

7,8-Dihydroxyflavone Ameliorates Cognitive Impairment by Inhibiting Expression of Tau Pathology in ApoE-Knockout Mice.

Tan Y, Nie S, Zhu W, Liu F, Guo H, Chu J, Cao XB, Jiang X, Zhang Y, Li Y.

Front Aging Neurosci. 2016 Nov 29;8:287.

PMID:
27965573
3.

Self-Reported Sleep Apnea and Dementia Risk: Findings from the Prevention of Alzheimer's Disease with Vitamin E and Selenium Trial.

Ding X, Kryscio RJ, Turner J, Jicha GA, Cooper G, Caban-Holt A, Schmitt FA, Abner EL.

J Am Geriatr Soc. 2016 Dec;64(12):2472-2478. doi: 10.1111/jgs.14393.

PMID:
27801937
4.

Human Central Nervous System (CNS) ApoE Isoforms Are Increased by Age, Differentially Altered by Amyloidosis, and Relative Amounts Reversed in the CNS Compared with Plasma.

Baker-Nigh AT, Mawuenyega KG, Bollinger JG, Ovod V, Kasten T, Franklin EE, Liao F, Jiang H, Holtzman D, Cairns NJ, Morris JC, Bateman RJ.

J Biol Chem. 2016 Dec 30;291(53):27204-27218. doi: 10.1074/jbc.M116.721779.

PMID:
27793990
5.

Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both Aβ and Tau pathologies.

Li C, Guo XD, Lei M, Wu JY, Jin JZ, Shi XF, Zhu ZY, Rukachaisirikul V, Hu LH, Wen TQ, Shen X.

Acta Pharmacol Sin. 2017 Jan;38(1):9-28. doi: 10.1038/aps.2016.94.

PMID:
27694908
6.

Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors.

Uchoa MF, Moser VA, Pike CJ.

Front Neuroendocrinol. 2016 Oct;43:60-82. doi: 10.1016/j.yfrne.2016.09.001. Review.

PMID:
27651175
7.

Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes.

Fan J, Zareyan S, Zhao W, Shimizu Y, Pfeifer TA, Tak JH, Isman MB, Van den Hoven B, Duggan ME, Wood MW, Wellington CL, Kulic I.

PLoS One. 2016 Sep 6;11(9):e0162384. doi: 10.1371/journal.pone.0162384.

PMID:
27598782
8.

Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid β production and clearance.

Guo XD, Sun GL, Zhou TT, Xu X, Zhu ZY, Rukachaisirikul V, Hu LH, Shen X.

Acta Pharmacol Sin. 2016 Sep;37(10):1281-1297. doi: 10.1038/aps.2016.80.

PMID:
27569389
9.

Transporters as Drug Targets in Neurological Diseases.

Qosa H, Mohamed LA, Alqahtani S, Abuasal BS, Hill RA, Kaddoumi A.

Clin Pharmacol Ther. 2016 Nov;100(5):441-453. doi: 10.1002/cpt.435.

PMID:
27447939
10.

The endocytic pathway in microglia during health, aging and Alzheimer's disease.

Solé-Domènech S, Cruz DL, Capetillo-Zarate E, Maxfield FR.

Ageing Res Rev. 2016 Dec;32:89-103. doi: 10.1016/j.arr.2016.07.002. Review.

PMID:
27421577
11.

A Genetic Variant of the Sortilin 1 Gene is Associated with Reduced Risk of Alzheimer's Disease.

Andersson CH, Hansson O, Minthon L, Andreasen N, Blennow K, Zetterberg H, Skoog I, Wallin A, Nilsson S, Kettunen P.

J Alzheimers Dis. 2016 Jul 1;53(4):1353-63. doi: 10.3233/JAD-160319.

PMID:
27392867
12.

Analysis of the Relationship between Estradiol and Follicle-Stimulating Hormone Concentrations and Polymorphisms of Apolipoprotein E and LeptinGenes in Women Post-Menopause.

Rył A, Jasiewicz A, Grzywacz A, Adler G, Skonieczna-Żydecka K, Rotter I, Sipak-Szmigiel O, Rumianowski B, Karakiewicz B, Jurczak A, Parczewski M, Urbańska A, Grabowska M, Laszczyńska M.

Int J Environ Res Public Health. 2016 May 28;13(6). pii: E543. doi: 10.3390/ijerph13060543.

PMID:
27240396
13.

Effect of LXR/RXR agonism on brain and CSF Aβ40 levels in rats.

Wang S, Wen P, Wood S.

Version 2. F1000Res. 2016 Feb 4 [revised 2016 Jan 1];5:138. doi: 10.12688/f1000research.7868.2.

PMID:
27239272
14.

Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia.

Bao J, Zheng L, Zhang Q, Li X, Zhang X, Li Z, Bai X, Zhang Z, Huo W, Zhao X, Shang S, Wang Q, Zhang C, Ji J.

Protein Cell. 2016 Jun;7(6):417-33. doi: 10.1007/s13238-016-0269-2.

PMID:
27209302
15.

MicroRNAs in brain cholesterol metabolism and their implications for Alzheimer's disease.

Yoon H, Flores LF, Kim J.

Biochim Biophys Acta. 2016 Dec;1861(12 Pt B):2139-2147. doi: 10.1016/j.bbalip.2016.04.020.

PMID:
27155217
16.

Neuropsychiatric symptoms and Apolipoprotein E: Associations with eventual Alzheimer's disease development.

Burke SL, Maramaldi P, Cadet T, Kukull W.

Arch Gerontol Geriatr. 2016 Jul-Aug;65:231-8. doi: 10.1016/j.archger.2016.04.006.

PMID:
27111252
17.

RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers.

Nam KN, Mounier A, Fitz NF, Wolfe C, Schug J, Lefterov I, Koldamova R.

Sci Rep. 2016 Apr 7;6:24048. doi: 10.1038/srep24048.

PMID:
27051978
18.

Clusterin Binds to Aβ1-42 Oligomers with High Affinity and Interferes with Peptide Aggregation by Inhibiting Primary and Secondary Nucleation.

Beeg M, Stravalaci M, Romeo M, Carrá AD, Cagnotto A, Rossi A, Diomede L, Salmona M, Gobbi M.

J Biol Chem. 2016 Mar 25;291(13):6958-66. doi: 10.1074/jbc.M115.689539.

PMID:
26884339
19.

Genetic and Transcriptomic Profiles of Inflammation in Neurodegenerative Diseases: Alzheimer, Parkinson, Creutzfeldt-Jakob and Tauopathies.

López González I, Garcia-Esparcia P, Llorens F, Ferrer I.

Int J Mol Sci. 2016 Feb 4;17(2):206. doi: 10.3390/ijms17020206. Review.

PMID:
26861289
20.

Association of a BACE1 Gene Polymorphism with Parkinson's Disease in a Norwegian Population.

Lange J, Lunde KA, Sletten C, Møller SG, Tysnes OB, Alves G, Larsen JP, Maple-Grødem J.

Parkinsons Dis. 2015;2015:973298. doi: 10.1155/2015/973298.

PMID:
26788404
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