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Items: 16


Phosphorylation of Minichromosome Maintenance 3 (MCM3) by Checkpoint Kinase 1 (Chk1) Negatively Regulates DNA Replication and Checkpoint Activation.

Han X, Mayca Pozo F, Wisotsky JN, Wang B, Jacobberger JW, Zhang Y.

J Biol Chem. 2015 May 8;290(19):12370-8. doi: 10.1074/jbc.M114.621532. Epub 2015 Mar 25.


Role of Myc in hepatocellular proliferation and hepatocarcinogenesis.

Qu A, Jiang C, Cai Y, Kim JH, Tanaka N, Ward JM, Shah YM, Gonzalez FJ.

J Hepatol. 2014 Feb;60(2):331-8. doi: 10.1016/j.jhep.2013.09.024. Epub 2013 Oct 2.


Over expression of minichromosome maintenance genes is clinically correlated to cervical carcinogenesis.

Das M, Prasad SB, Yadav SS, Govardhan HB, Pandey LK, Singh S, Pradhan S, Narayan G.

PLoS One. 2013 Jul 17;8(7):e69607. doi: 10.1371/journal.pone.0069607. Print 2013.


Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers.

Huang TH, Huo L, Wang YN, Xia W, Wei Y, Chang SS, Chang WC, Fang YF, Chen CT, Lang JY, Tu C, Wang Y, Hsu MC, Kuo HP, Ko HW, Shen J, Lee HH, Lee PC, Wu Y, Chen CH, Hung MC.

Cancer Cell. 2013 Jun 10;23(6):796-810. doi: 10.1016/j.ccr.2013.04.027.


Phosphorylation of minichromosome maintenance protein 7 (MCM7) by cyclin/cyclin-dependent kinase affects its function in cell cycle regulation.

Wei Q, Li J, Liu T, Tong X, Ye X.

J Biol Chem. 2013 Jul 5;288(27):19715-25. doi: 10.1074/jbc.M112.449652. Epub 2013 May 17.


Clustered DNA damage induces pan-nuclear H2AX phosphorylation mediated by ATM and DNA-PK.

Meyer B, Voss KO, Tobias F, Jakob B, Durante M, Taucher-Scholz G.

Nucleic Acids Res. 2013 Jul;41(12):6109-18. doi: 10.1093/nar/gkt304. Epub 2013 Apr 24.


Genome wide comparative comprehensive analysis of Plasmodium falciparum MCM family with human host.

Ansari A, Tuteja R.

Commun Integr Biol. 2012 Nov 1;5(6):607-15. doi: 10.4161/cib.21759.


The cellular protein MCM3AP is required for inhibition of cellular DNA synthesis by the IE86 protein of human cytomegalovirus.

Poole E, Bain M, Teague L, Takei Y, Laskey R, Sinclair J.

PLoS One. 2012;7(10):e45686. doi: 10.1371/journal.pone.0045686. Epub 2012 Oct 19.


Checkpoint kinase 2 (Chk2) inhibits the activity of the Cdc45/MCM2-7/GINS (CMG) replicative helicase complex.

Ilves I, Tamberg N, Botchan MR.

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13163-70. doi: 10.1073/pnas.1211525109. Epub 2012 Aug 1.


Histone demethylase Kdm4b functions as a co-factor of C/EBPβ to promote mitotic clonal expansion during differentiation of 3T3-L1 preadipocytes.

Guo L, Li X, Huang JX, Huang HY, Zhang YY, Qian SW, Zhu H, Zhang YD, Liu Y, Liu Y, Wang KK, Tang QQ.

Cell Death Differ. 2012 Dec;19(12):1917-27. doi: 10.1038/cdd.2012.75. Epub 2012 Jun 22.


Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells.

Chuang CH, Yang D, Bai G, Freeland A, Pruitt SC, Schimenti JC.

Nucleic Acids Res. 2012 Jun;40(11):4914-24. doi: 10.1093/nar/gks176. Epub 2012 Feb 22.


Phosphorylation of MCM3 protein by cyclin E/cyclin-dependent kinase 2 (Cdk2) regulates its function in cell cycle.

Li J, Deng M, Wei Q, Liu T, Tong X, Ye X.

J Biol Chem. 2011 Nov 18;286(46):39776-85. doi: 10.1074/jbc.M111.226464. Epub 2011 Sep 30.


MCM proteins are negative regulators of hypoxia-inducible factor 1.

Hubbi ME, Luo W, Baek JH, Semenza GL.

Mol Cell. 2011 Jun 10;42(5):700-12. doi: 10.1016/j.molcel.2011.03.029.


Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress.

Chuang CH, Wallace MD, Abratte C, Southard T, Schimenti JC.

PLoS Genet. 2010 Sep 9;6(9):e1001110. doi: 10.1371/journal.pgen.1001110.


The Mcm complex: unwinding the mechanism of a replicative helicase.

Bochman ML, Schwacha A.

Microbiol Mol Biol Rev. 2009 Dec;73(4):652-83. doi: 10.1128/MMBR.00019-09. Review.


Identification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17.

Deng M, Li F, Ballif BA, Li S, Chen X, Guo L, Ye X.

J Biol Chem. 2009 Mar 20;284(12):7875-88. doi: 10.1074/jbc.M807827200. Epub 2009 Jan 16.

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