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Items: 18


Ototoxicity-induced loss of hearing and inner hair cells is attenuated by HSP70 gene transfer.

Takada Y, Takada T, Lee MY, Swiderski DL, Kabara LL, Dolan DF, Raphael Y.

Mol Ther Methods Clin Dev. 2015 May 27;2:15019. doi: 10.1038/mtm.2015.19. eCollection 2015.


Heat shock protein-mediated protection against Cisplatin-induced hair cell death.

Baker TG, Roy S, Brandon CS, Kramarenko IK, Francis SP, Taleb M, Marshall KM, Schwendener R, Lee FS, Cunningham LL.

J Assoc Res Otolaryngol. 2015 Feb;16(1):67-80. doi: 10.1007/s10162-014-0491-7. Epub 2014 Sep 27.


Cisplatin exposure damages resident stem cells of the mammalian inner ear.

Slattery EL, Oshima K, Heller S, Warchol ME.

Dev Dyn. 2014 Oct;243(10):1328-37. doi: 10.1002/dvdy.24150. Epub 2014 Jun 25.


Sound preconditioning therapy inhibits ototoxic hearing loss in mice.

Roy S, Ryals MM, Van den Bruele AB, Fitzgerald TS, Cunningham LL.

J Clin Invest. 2013 Nov;123(11):4945-9. Erratum in: J Clin Invest. 2014 Jan 2;124(1):461.


Inner ear supporting cells protect hair cells by secreting HSP70.

May LA, Kramarenko II, Brandon CS, Voelkel-Johnson C, Roy S, Truong K, Francis SP, Monzack EL, Lee FS, Cunningham LL.

J Clin Invest. 2013 Aug;123(8):3577-87. doi: 10.1172/JCI68480. Epub 2013 Jul 25.


Bax, Bcl2, and p53 differentially regulate neomycin- and gentamicin-induced hair cell death in the zebrafish lateral line.

Coffin AB, Rubel EW, Raible DW.

J Assoc Res Otolaryngol. 2013 Oct;14(5):645-59. doi: 10.1007/s10162-013-0404-1. Epub 2013 Jul 3.


Blockade of PI3K/AKT pathway enhances sensitivity of Raji cells to chemotherapy through down-regulation of HSP70.

Fang X, Jiang Y, Feng L, Chen H, Zhen C, Ding M, Wang X.

Cancer Cell Int. 2013 May 24;13(1):48. doi: 10.1186/1475-2867-13-48.


Dissection of adult mouse utricle and adenovirus-mediated supporting-cell infection.

Brandon CS, Voelkel-Johnson C, May LA, Cunningham LL.

J Vis Exp. 2012 Mar 28;(61). pii: 3734. doi: 10.3791/3734.


Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.

Huth ME, Ricci AJ, Cheng AG.

Int J Otolaryngol. 2011;2011:937861. doi: 10.1155/2011/937861. Epub 2011 Oct 25.


Induction of heat shock proteins by hyperthermia and noise overstimulation in hsf1 -/- mice.

Gong TW, Fairfield DA, Fullarton L, Dolan DF, Altschuler RA, Kohrman DC, Lomax MI.

J Assoc Res Otolaryngol. 2012 Feb;13(1):29-37. doi: 10.1007/s10162-011-0289-9. Epub 2011 Sep 20.


Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32.

Francis SP, Kramarenko II, Brandon CS, Lee FS, Baker TG, Cunningham LL.

Cell Death Dis. 2011 Aug 25;2:e195. doi: 10.1038/cddis.2011.76.


Intracellular mechanisms of aminoglycoside-induced cytotoxicity.

Karasawa T, Steyger PS.

Integr Biol (Camb). 2011 Sep;3(9):879-86. doi: 10.1039/c1ib00034a. Epub 2011 Jul 29. Review.


Expression of fractalkine receptor CX3CR1 on cochlear macrophages influences survival of hair cells following ototoxic injury.

Sato E, Shick HE, Ransohoff RM, Hirose K.

J Assoc Res Otolaryngol. 2010 Jun;11(2):223-34. doi: 10.1007/s10162-009-0198-3. Epub 2009 Nov 21.


Extracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral line.

Coffin AB, Reinhart KE, Owens KN, Raible DW, Rubel EW.

Hear Res. 2009 Jul;253(1-2):42-51. doi: 10.1016/j.heares.2009.03.004. Epub 2009 Mar 12.


Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways.

Owens KN, Coffin AB, Hong LS, Bennett KO, Rubel EW, Raible DW.

Hear Res. 2009 Jul;253(1-2):32-41. doi: 10.1016/j.heares.2009.03.001. Epub 2009 Mar 11.


Hsp70 inhibits aminoglycoside-induced hearing loss and cochlear hair cell death.

Taleb M, Brandon CS, Lee FS, Harris KC, Dillmann WH, Cunningham LL.

Cell Stress Chaperones. 2009 Jul;14(4):427-37. doi: 10.1007/s12192-008-0097-2. Epub 2009 Jan 15.

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