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Items: 1 to 20 of 277

1.

Rottlerin exhibits anti-cancer effect through inactivation of S phase kinase-associated protein 2 in pancreatic cancer cells.

Su J, Wang L, Yin X, Zhao Z, Hou Y, Ye X, Zhou X, Wang Z.

Am J Cancer Res. 2016 Oct 1;6(10):2178-2191.

2.

HBV core promoter mutations and AKT upregulate S-phase kinase-associated protein 2 to promote postoperative hepatocellular carcinoma progression.

Chen L, Gu L, Gu Y, Wang H, Deng M, Stamataki Z, Oo YH, Huang Y.

Sci Rep. 2016 Oct 25;6:35917. doi: 10.1038/srep35917.

3.
4.

Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex.

Ding S, Mooney N, Li B, Kelly MR, Feng N, Loktev AV, Sen A, Patton JT, Jackson PK, Greenberg HB.

PLoS Pathog. 2016 Oct 5;12(10):e1005929. doi: 10.1371/journal.ppat.1005929.

5.

Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner.

Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, Malumbres M, Liu J, Zou W, Wei W.

Cell Discov. 2016 Feb 2;2:15044. doi: 10.1038/celldisc.2015.44.

6.

Copy number variation of E3 ubiquitin ligase genes in peripheral blood leukocyte and colorectal cancer.

Bi H, Tian T, Zhu L, Zhou H, Hu H, Liu Y, Li X, Hu F, Zhao Y, Wang G.

Sci Rep. 2016 Jul 15;6:29869. doi: 10.1038/srep29869.

7.

Identification of key genes in glioblastoma-associated stromal cells using bioinformatics analysis.

Chen C, Sun C, Tang D, Yang G, Zhou X, Wang D.

Oncol Lett. 2016 Jun;11(6):3999-4007.

8.

Systematic analysis of mutation distribution in three dimensional protein structures identifies cancer driver genes.

Fujimoto A, Okada Y, Boroevich KA, Tsunoda T, Taniguchi H, Nakagawa H.

Sci Rep. 2016 May 26;6:26483. doi: 10.1038/srep26483.

9.

Recent advances in SCF ubiquitin ligase complex: Clinical implications.

Zheng N, Zhou Q, Wang Z, Wei W.

Biochim Biophys Acta. 2016 Aug;1866(1):12-22. doi: 10.1016/j.bbcan.2016.05.001. Review.

PMID:
27156687
10.

Fbxo30 Regulates Mammopoiesis by Targeting the Bipolar Mitotic Kinesin Eg5.

Liu Y, Wang Y, Du Z, Yan X, Zheng P, Liu Y.

Cell Rep. 2016 May 3;15(5):1111-22. doi: 10.1016/j.celrep.2016.03.083.

11.

Equol inhibits prostate cancer growth through degradation of androgen receptor by S-phase kinase-associated protein 2.

Itsumi M, Shiota M, Takeuchi A, Kashiwagi E, Inokuchi J, Tatsugami K, Kajioka S, Uchiumi T, Naito S, Eto M, Yokomizo A.

Cancer Sci. 2016 Jul;107(7):1022-8. doi: 10.1111/cas.12948.

12.

Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1.

Lin Z, Tan C, Qiu Q, Kong S, Yang H, Zhao F, Liu Z, Li J, Kong Q, Gao B, Barrett T, Yang GY, Zhang J, Fang D.

Cell Discov. 2015;1. pii: 15028.

13.

β-TrCP-mediated ubiquitination and degradation of liver-enriched transcription factor CREB-H.

Cheng Y, Gao WW, Tang HM, Deng JJ, Wong CM, Chan CP, Jin DY.

Sci Rep. 2016 Mar 31;6:23938. doi: 10.1038/srep23938.

14.

Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteins.

Zheng N, Wang Z, Wei W.

Int J Biochem Cell Biol. 2016 Apr;73:99-110. doi: 10.1016/j.biocel.2016.02.005. Review.

PMID:
26860958
15.

Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System.

Guharoy M, Bhowmick P, Tompa P.

J Biol Chem. 2016 Mar 25;291(13):6723-31. doi: 10.1074/jbc.R115.692665. Review.

PMID:
26851277
16.

Protein Kinase R Degradation Is Essential for Rift Valley Fever Virus Infection and Is Regulated by SKP1-CUL1-F-box (SCF)FBXW11-NSs E3 Ligase.

Mudhasani R, Tran JP, Retterer C, Kota KP, Whitehouse CA, Bavari S.

PLoS Pathog. 2016 Feb 2;12(2):e1005437. doi: 10.1371/journal.ppat.1005437.

17.

Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1.

Taniue K, Kurimoto A, Sugimasa H, Nasu E, Takeda Y, Iwasaki K, Nagashima T, Okada-Hatakeyama M, Oyama M, Kozuka-Hata H, Hiyoshi M, Kitayama J, Negishi L, Kawasaki Y, Akiyama T.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1273-8. doi: 10.1073/pnas.1500992113.

18.

Skp2 is required for Aurora B activation in cell mitosis and spindle checkpoint.

Wu J, Huang YF, Zhou XK, Zhang W, Lian YF, Lv XB, Gao XR, Lin HK, Zeng YX, Huang JQ.

Cell Cycle. 2015;14(24):3877-84. doi: 10.1080/15384101.2015.1120916.

PMID:
26697838
19.

Histone Deacetylase Inhibitors Increase p27(Kip1) by Affecting Its Ubiquitin-Dependent Degradation through Skp2 Downregulation.

Borriello A, Naviglio S, Bencivenga D, Caldarelli I, Tramontano A, Speranza MC, Stampone E, Sapio L, Negri A, Oliva A, Sinisi AA, Spina A, Della Ragione F.

Oxid Med Cell Longev. 2016;2016:2481865. doi: 10.1155/2016/2481865.

20.

SCF(β-TRCP) promotes cell growth by targeting PR-Set7/Set8 for degradation.

Wang Z, Dai X, Zhong J, Inuzuka H, Wan L, Li X, Wang L, Ye X, Sun L, Gao D, Zou L, Wei W.

Nat Commun. 2015 Dec 15;6:10185. doi: 10.1038/ncomms10185.

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