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Items: 15

1.

EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism.

Modernelli A, Naponelli V, Giovanna Troglio M, Bonacini M, Ramazzina I, Bettuzzi S, Rizzi F.

Sci Rep. 2015 Oct 16;5:15270. doi: 10.1038/srep15270.

2.

IKK inhibition increases bortezomib effectiveness in ovarian cancer.

Singha B, Gatla HR, Phyo S, Patel A, Chen ZS, Vancurova I.

Oncotarget. 2015 Sep 22;6(28):26347-58. doi: 10.18632/oncotarget.4613.

3.

Nuclear factor-kappa B regulates pain and COMT expression in a rodent model of inflammation.

Hartung JE, Eskew O, Wong T, Tchivileva IE, Oladosu FA, O'Buckley SC, Nackley AG.

Brain Behav Immun. 2015 Nov;50:196-202. doi: 10.1016/j.bbi.2015.07.014. Epub 2015 Jul 15.

4.

Bcl3 regulates pro-survival and pro-inflammatory gene expression in cutaneous T-cell lymphoma.

Chang TP, Vancurova I.

Biochim Biophys Acta. 2014 Nov;1843(11):2620-30. doi: 10.1016/j.bbamcr.2014.07.012. Epub 2014 Jul 30.

5.

Proteasome inhibition increases recruitment of IκB kinase β (IKKβ), S536P-p65, and transcription factor EGR1 to interleukin-8 (IL-8) promoter, resulting in increased IL-8 production in ovarian cancer cells.

Singha B, Gatla HR, Manna S, Chang TP, Sanacora S, Poltoratsky V, Vancura A, Vancurova I.

J Biol Chem. 2014 Jan 31;289(5):2687-700. doi: 10.1074/jbc.M113.502641. Epub 2013 Dec 11.

6.

NFκB function and regulation in cutaneous T-cell lymphoma.

Chang TP, Vancurova I.

Am J Cancer Res. 2013 Nov 1;3(5):433-45. Review.

7.
8.

Proteasome inhibition by bortezomib increases IL-8 expression in androgen-independent prostate cancer cells: the role of IKKα.

Manna S, Singha B, Phyo SA, Gatla HR, Chang TP, Sanacora S, Ramaswami S, Vancurova I.

J Immunol. 2013 Sep 1;191(5):2837-46. doi: 10.4049/jimmunol.1300895. Epub 2013 Jul 26.

9.

Regulation and function of nuclear IκBα in inflammation and cancer.

Vancurova I, Vancura A.

Am J Clin Exp Immunol. 2012 May 25;1(1):56-66. Print 2012.

10.

TRIM13 (RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NF Kappa B pathway and proteasome activity.

Gatt ME, Takada K, Mani M, Lerner M, Pick M, Hideshima T, Carrasco DE, Protopopov A, Ivanova E, Sangfelt O, Grandér D, Barlogie B, Shaughnessy JD Jr, Anderson KC, Carrasco DR.

Br J Haematol. 2013 Jul;162(2):210-20. doi: 10.1111/bjh.12365. Epub 2013 May 7.

11.

Caspase control: protagonists of cancer cell apoptosis.

Fiandalo MV, Kyprianou N.

Exp Oncol. 2012 Oct;34(3):165-75. Review.

12.

Bortezomib induces nuclear translocation of IκBα resulting in gene-specific suppression of NF-κB--dependent transcription and induction of apoptosis in CTCL.

Juvekar A, Manna S, Ramaswami S, Chang TP, Vu HY, Ghosh CC, Celiker MY, Vancurova I.

Mol Cancer Res. 2011 Feb;9(2):183-94. doi: 10.1158/1541-7786.MCR-10-0368. Epub 2011 Jan 11.

13.

Cancer biomarker discovery: the entropic hallmark.

Berretta R, Moscato P.

PLoS One. 2010 Aug 18;5(8):e12262. doi: 10.1371/journal.pone.0012262.

14.

Gene-specific repression of proinflammatory cytokines in stimulated human macrophages by nuclear IκBα.

Ghosh CC, Ramaswami S, Juvekar A, Vu HY, Galdieri L, Davidson D, Vancurova I.

J Immunol. 2010 Sep 15;185(6):3685-93. doi: 10.4049/jimmunol.0902230. Epub 2010 Aug 9.

15.

Proteasome inhibition modulates kinase activation in neural cells: relevance to ubiquitination, ribosomes, and survival.

Zhang L, Ebenezer PJ, Dasuri K, Bruce-Keller AJ, Liu Y, Keller JN.

J Neurosci Res. 2009 Nov 1;87(14):3231-8. doi: 10.1002/jnr.22147.

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