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Items: 20

1.

Targeting Interleukin-2-Inducible T-cell Kinase (ITK) in T-Cell Related Diseases.

Zhong Y, Johnson AJ, Byrd JC, Dubovsky JA.

Postdoc J. 2014 Jun;2(6):1-11.

2.

Dynamics of the Tec-family tyrosine kinase SH3 domains.

Roberts JM, Tarafdar S, Joseph RE, Andreotti AH, Smithgall TE, Engen JR, Wales TE.

Protein Sci. 2016 Apr;25(4):852-64. doi: 10.1002/pro.2887. Epub 2016 Mar 18.

3.

Role of Bruton's tyrosine kinase inhibitors in HIV-1-infected cells.

Guendel I, Iordanskiy S, Sampey GC, Van Duyne R, Calvert V, Petricoin E, Saifuddin M, Kehn-Hall K, Kashanchi F.

J Neurovirol. 2015 Jun;21(3):257-75. doi: 10.1007/s13365-015-0323-5. Epub 2015 Feb 12.

4.

Interleukin-2-inducible T-cell kinase (ITK) deficiency - clinical and molecular aspects.

Ghosh S, Bienemann K, Boztug K, Borkhardt A.

J Clin Immunol. 2014 Nov;34(8):892-9. doi: 10.1007/s10875-014-0110-8. Epub 2014 Oct 24. Review.

5.

The accessory factor Nef links HIV-1 to Tec/Btk kinases in an Src homology 3 domain-dependent manner.

Tarafdar S, Poe JA, Smithgall TE.

J Biol Chem. 2014 May 30;289(22):15718-28. doi: 10.1074/jbc.M114.572099. Epub 2014 Apr 10.

6.

CD28 and ITK signals regulate autoreactive T cell trafficking.

Jain N, Miu B, Jiang JK, McKinstry KK, Prince A, Swain SL, Greiner DL, Thomas CJ, Sanderson MJ, Berg LJ, Kang J.

Nat Med. 2013 Dec;19(12):1632-7. doi: 10.1038/nm.3393. Epub 2013 Nov 24.

7.

Immune adaptor ADAP in T cells regulates HIV-1 transcription and cell-cell viral spread via different co-receptors.

Wei B, Han L, Abbink TE, Groppelli E, Lim D, Thaker YR, Gao W, Zhai R, Wang J, Lever A, Jolly C, Wang H, Rudd CE.

Retrovirology. 2013 Sep 18;10:101. doi: 10.1186/1742-4690-10-101.

8.

Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes.

Dubovsky JA, Beckwith KA, Natarajan G, Woyach JA, Jaglowski S, Zhong Y, Hessler JD, Liu TM, Chang BY, Larkin KM, Stefanovski MR, Chappell DL, Frissora FW, Smith LL, Smucker KA, Flynn JM, Jones JA, Andritsos LA, Maddocks K, Lehman AM, Furman R, Sharman J, Mishra A, Caligiuri MA, Satoskar AR, Buggy JJ, Muthusamy N, Johnson AJ, Byrd JC.

Blood. 2013 Oct 10;122(15):2539-49. doi: 10.1182/blood-2013-06-507947. Epub 2013 Jul 25.

9.

Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.

Schiralli Lester GM, Akiyama H, Evans E, Singh J, Gummuluru S, Henderson AJ.

Virology. 2013 Feb 5;436(1):235-43. doi: 10.1016/j.virol.2012.11.015. Epub 2012 Dec 20.

10.

Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs.

Guo W, Liu R, Ono Y, Ma AH, Martinez A, Sanchez E, Wang Y, Huang W, Mazloom A, Li J, Ning J, Maverakis E, Lam KS, Kung HJ.

Mol Pharmacol. 2012 Nov;82(5):938-47. doi: 10.1124/mol.112.079889. Epub 2012 Aug 16.

11.

The trinity of the cortical actin in the initiation of HIV-1 infection.

Spear M, Guo J, Wu Y.

Retrovirology. 2012 May 28;9:45. doi: 10.1186/1742-4690-9-45. Review.

12.

The adaptor protein SLP-76 regulates HIV-1 release and cell-to-cell transmission in T cells.

Nagaraja T, Anand AR, Zhao H, Ganju RK.

J Immunol. 2012 Mar 15;188(6):2769-77. doi: 10.4049/jimmunol.1102106. Epub 2012 Feb 8.

13.

Integrin signalling and function in immune cells.

Zhang Y, Wang H.

Immunology. 2012 Apr;135(4):268-75. doi: 10.1111/j.1365-2567.2011.03549.x. Review.

14.

Itk: the rheostat of the T cell response.

Grasis JA, Tsoukas CD.

J Signal Transduct. 2011;2011:297868. doi: 10.1155/2011/297868. Epub 2011 Apr 7.

15.

Combinatorial signals from CD28 differentially regulate human immunodeficiency virus transcription in T cells.

Natarajan M, August A, Henderson AJ.

J Biol Chem. 2010 Jun 4;285(23):17338-47. doi: 10.1074/jbc.M109.085324. Epub 2010 Apr 5.

16.

IL-2-inducible T-cell kinase (ITK) finds another (dance) partner...TFII-I.

August A.

Eur J Immunol. 2009 Sep;39(9):2354-7. doi: 10.1002/eji.200939813.

17.

Proteasome inactivation promotes p38 mitogen-activated protein kinase-dependent phosphatidylinositol 3-kinase activation and increases interleukin-8 production in retinal pigment epithelial cells.

Fernandes AF, Bian Q, Jiang JK, Thomas CJ, Taylor A, Pereira P, Shang F.

Mol Biol Cell. 2009 Aug;20(16):3690-9. doi: 10.1091/mbc.E08-10-1068. Epub 2009 Jul 1.

18.

Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain.

Severin A, Joseph RE, Boyken S, Fulton DB, Andreotti AH.

J Mol Biol. 2009 Apr 3;387(3):726-43. doi: 10.1016/j.jmb.2009.02.012. Epub 2009 Feb 12.

19.

Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk.

Readinger JA, Mueller KL, Venegas AM, Horai R, Schwartzberg PL.

Immunol Rev. 2009 Mar;228(1):93-114. doi: 10.1111/j.1600-065X.2008.00757.x. Review.

20.

The Src kinase Lck facilitates assembly of HIV-1 at the plasma membrane.

Strasner AB, Natarajan M, Doman T, Key D, August A, Henderson AJ.

J Immunol. 2008 Sep 1;181(5):3706-13.

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