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Items: 1 to 20 of 67

1.

The Circadian Rhythm Gene Arntl2 Is a Metastasis Susceptibility Gene for Estrogen Receptor-Negative Breast Cancer.

Ha NH, Long J, Cai Q, Shu XO, Hunter KW.

PLoS Genet. 2016 Sep 22;12(9):e1006267. doi: 10.1371/journal.pgen.1006267.

2.

Bromodomain 4: a cellular Swiss army knife.

Devaiah BN, Gegonne A, Singer DS.

J Leukoc Biol. 2016 Oct;100(4):679-686. Review.

PMID:
27450555
3.

BET and BRAF inhibitors act synergistically against BRAF-mutant melanoma.

Paoluzzi L, Hanniford D, Sokolova E, Osman I, Darvishian F, Wang J, Bradner JE, Hernando E.

Cancer Med. 2016 Jun;5(6):1183-93. doi: 10.1002/cam4.667.

4.

Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7.

Faraji F, Hu Y, Yang HH, Lee MP, Winkler GS, Hafner M, Hunter KW.

PLoS Genet. 2016 Jan 25;12(1):e1005820. doi: 10.1371/journal.pgen.1005820.

5.

Small Molecule Modulators of Pre-mRNA Splicing in Cancer Therapy.

Salton M, Misteli T.

Trends Mol Med. 2016 Jan;22(1):28-37. doi: 10.1016/j.molmed.2015.11.005. Review.

PMID:
26700537
6.

Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.

Zhang L, Tran NT, Su H, Wang R, Lu Y, Tang H, Aoyagi S, Guo A, Khodadadi-Jamayran A, Zhou D, Qian K, Hricik T, Côté J, Han X, Zhou W, Laha S, Abdel-Wahab O, Levine RL, Raffel G, Liu Y, Chen D, Li H, Townes T, Wang H, Deng H, Zheng YG, Leslie C, Luo M, Zhao X.

Elife. 2015 Nov 17;4. pii: e07938. doi: 10.7554/eLife.07938.

7.

Failure to interact with Brd4 alters the ability of HPV16 E2 to regulate host genome expression and cellular movement.

Gauson EJ, Wang X, Dornan ES, Herzyk P, Bristol M, Morgan IM.

Virus Res. 2016 Jan 4;211:1-8. doi: 10.1016/j.virusres.2015.09.008.

8.

The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains.

Alekseyenko AA, Walsh EM, Wang X, Grayson AR, Hsi PT, Kharchenko PV, Kuroda MI, French CA.

Genes Dev. 2015 Jul 15;29(14):1507-23. doi: 10.1101/gad.267583.115.

9.
10.

H4K12ac is regulated by estrogen receptor-alpha and is associated with BRD4 function and inducible transcription.

Nagarajan S, Benito E, Fischer A, Johnsen SA.

Oncotarget. 2015 Mar 30;6(9):7305-17.

11.

BRD4 inhibitor inhibits colorectal cancer growth and metastasis.

Hu Y, Zhou J, Ye F, Xiong H, Peng L, Zheng Z, Xu F, Cui M, Wei C, Wang X, Wang Z, Zhu H, Lee P, Zhou M, Jiang B, Zhang DY.

Int J Mol Sci. 2015 Jan 16;16(1):1928-48. doi: 10.3390/ijms16011928.

12.
13.

Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma.

Hackett CS, Quigley DA, Wong RA, Chen J, Cheng C, Song YK, Wei JS, Pawlikowska L, Bao Y, Goldenberg DD, Nguyen K, Gustafson WC, Rallapalli SK, Cho YJ, Cook JM, Kozlov S, Mao JH, Van Dyke T, Kwok PY, Khan J, Balmain A, Fan Q, Weiss WA.

Cell Rep. 2014 Nov 6;9(3):1034-46. doi: 10.1016/j.celrep.2014.09.046.

14.

"Glowing head" mice: a genetic tool enabling reliable preclinical image-based evaluation of cancers in immunocompetent allografts.

Day CP, Carter J, Weaver Ohler Z, Bonomi C, El Meskini R, Martin P, Graff-Cherry C, Feigenbaum L, Tüting T, Van Dyke T, Hollingshead M, Merlino G.

PLoS One. 2014 Nov 4;9(11):e109956. doi: 10.1371/journal.pone.0109956.

15.

Transformation resistance in a premature aging disorder identifies a tumor-protective function of BRD4.

Fernandez P, Scaffidi P, Markert E, Lee JH, Rane S, Misteli T.

Cell Rep. 2014 Oct 9;9(1):248-60. doi: 10.1016/j.celrep.2014.08.069.

16.

Understanding susceptibility to breast cancer metastasis: the genetic approach.

Shukla A, Alsarraj J, Hunter K.

Breast Cancer Manag. 2014 Mar 1;3(2):165-172.

17.

BRD4 regulates Nanog expression in mouse embryonic stem cells and preimplantation embryos.

Liu W, Stein P, Cheng X, Yang W, Shao NY, Morrisey EE, Schultz RM, You J.

Cell Death Differ. 2014 Dec;21(12):1950-60. doi: 10.1038/cdd.2014.124.

18.

Metastasis-associated protein ribosomal RNA processing 1 homolog B (RRP1B) modulates metastasis through regulation of histone methylation.

Lee M, Dworkin AM, Lichtenberg J, Patel SJ, Trivedi NS, Gildea D, Bodine DM, Crawford NP.

Mol Cancer Res. 2014 Dec;12(12):1818-28. doi: 10.1158/1541-7786.MCR-14-0167.

19.

Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription.

Nagarajan S, Hossan T, Alawi M, Najafova Z, Indenbirken D, Bedi U, Taipaleenmäki H, Ben-Batalla I, Scheller M, Loges S, Knapp S, Hesse E, Chiang CM, Grundhoff A, Johnsen SA.

Cell Rep. 2014 Jul 24;8(2):460-9. doi: 10.1016/j.celrep.2014.06.016.

20.

Writers and readers of histone acetylation: structure, mechanism, and inhibition.

Marmorstein R, Zhou MM.

Cold Spring Harb Perspect Biol. 2014 Jul 1;6(7):a018762. doi: 10.1101/cshperspect.a018762. Review.

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