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Items: 10


A double-strand break can trigger immunoglobulin gene conversion.

Bastianello G, Arakawa H.

Nucleic Acids Res. 2017 Jan 9;45(1):231-243. doi: 10.1093/nar/gkw887. Epub 2016 Oct 3.


Rapid prototyping of microbial cell factories via genome-scale engineering.

Si T, Xiao H, Zhao H.

Biotechnol Adv. 2015 Nov 15;33(7):1420-32. doi: 10.1016/j.biotechadv.2014.11.007. Epub 2014 Nov 20. Review.


Reprogramming homing endonuclease specificity through computational design and directed evolution.

Thyme SB, Boissel SJ, Arshiya Quadri S, Nolan T, Baker DA, Park RU, Kusak L, Ashworth J, Baker D.

Nucleic Acids Res. 2014 Feb;42(4):2564-76. doi: 10.1093/nar/gkt1212. Epub 2013 Nov 21.


The mitochondrial LSU rRNA group II intron of Ustilago maydis encodes an active homing endonuclease likely involved in intron mobility.

Pfeifer A, Martin B, Kämper J, Basse CW.

PLoS One. 2012;7(11):e49551. doi: 10.1371/journal.pone.0049551. Epub 2012 Nov 14.


Homing endonucleases: from microbial genetic invaders to reagents for targeted DNA modification.

Stoddard BL.

Structure. 2011 Jan 12;19(1):7-15. doi: 10.1016/j.str.2010.12.003. Review.


Evolution of I-SceI homing endonucleases with increased DNA recognition site specificity.

Joshi R, Ho KK, Tenney K, Chen JH, Golden BL, Gimble FS.

J Mol Biol. 2011 Jan 7;405(1):185-200. doi: 10.1016/j.jmb.2010.10.029. Epub 2010 Oct 26.


Natural and engineered nicking endonucleases--from cleavage mechanism to engineering of strand-specificity.

Chan SH, Stoddard BL, Xu SY.

Nucleic Acids Res. 2011 Jan;39(1):1-18. doi: 10.1093/nar/gkq742. Epub 2010 Aug 30. Review. Erratum in: Nucleic Acids Res. 2011 Mar 1;39(5):1966.


Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease.

McConnell Smith A, Takeuchi R, Pellenz S, Davis L, Maizels N, Monnat RJ Jr, Stoddard BL.

Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5099-104. doi: 10.1073/pnas.0810588106. Epub 2009 Mar 10.


Crystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineering.

Marcaida MJ, Prieto J, Redondo P, Nadra AD, Alibés A, Serrano L, Grizot S, Duchateau P, Pâques F, Blanco FJ, Montoya G.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):16888-93. doi: 10.1073/pnas.0804795105. Epub 2008 Oct 30.


Engineering variants of the I-SceI homing endonuclease with strand-specific and site-specific DNA-nicking activity.

Niu Y, Tenney K, Li H, Gimble FS.

J Mol Biol. 2008 Sep 26;382(1):188-202. doi: 10.1016/j.jmb.2008.07.010. Epub 2008 Jul 11.

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