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Update on biomarkers for the detection of lung cancer.

Jantus-Lewintre E, Usó M, Sanmartín E, Camps C.

Lung Cancer (Auckl). 2012 Jun 11;3:21-29. doi: 10.2147/LCTT.S23424. Review.


Differential expression of alternatively spliced transcripts related to energy metabolism in colorectal cancer.

Snezhkina AV, Krasnov GS, Zaretsky AR, Zhavoronkov A, Nyushko KM, Moskalev AA, Karpova IY, Afremova AI, Lipatova AV, Kochetkov DV, Fedorova MS, Volchenko NN, Sadritdinova AF, Melnikova NV, Sidorov DV, Popov AY, Kalinin DV, Kaprin AD, Alekseev BY, Dmitriev AA, Kudryavtseva AV.

BMC Genomics. 2016 Dec 28;17(Suppl 14):1011. doi: 10.1186/s12864-016-3351-5.


Epigenetics in non-small cell lung cancer: from basics to therapeutics.

Ansari J, Shackelford RE, El-Osta H.

Transl Lung Cancer Res. 2016 Apr;5(2):155-71. doi: 10.21037/tlcr.2016.02.02. Review.


Re-expression of Selected Epigenetically Silenced Candidate Tumor Suppressor Genes in Cervical Cancer by TET2-directed Demethylation.

Huisman C, van der Wijst MG, Schokker M, Blancafort P, Terpstra MM, Kok K, van der Zee AG, Schuuring E, Wisman GB, Rots MG.

Mol Ther. 2016 Mar;24(3):536-47. doi: 10.1038/mt.2015.226.


Epigenetic alteration of the purinergic type 7 receptor in salivary epithelial cells.

Shin YH, Kim M, Kim N, Choi SK, Namkoong E, Choi SY, Lee JH, Cha S, Park K.

Biochem Biophys Res Commun. 2015 Oct 30;466(4):704-10. doi: 10.1016/j.bbrc.2015.09.095.


Involvement of epigenetics and EMT-related miRNA in arsenic-induced neoplastic transformation and their potential clinical use.

Michailidi C, Hayashi M, Datta S, Sen T, Zenner K, Oladeru O, Brait M, Izumchenko E, Baras A, VandenBussche C, Argos M, Bivalacqua TJ, Ahsan H, Hahn NM, Netto GJ, Sidransky D, Hoque MO.

Cancer Prev Res (Phila). 2015 Mar;8(3):208-21. doi: 10.1158/1940-6207.CAPR-14-0251.


Dysregulation of cell cycle related genes and microRNAs distinguish the low- from high-risk of prostate cancer.

Wen J, Li R, Wen X, Chou G, Lu J, Wang X, Jin Y.

Diagn Pathol. 2014 Sep 26;9:156. doi: 10.1186/s13000-014-0156-1. Retraction in: Diagn Pathol. 2015;10:11.


Microarray-based DNA methylation study of Ewing's sarcoma of the bone.

Park HR, Jung WW, Kim HS, Park YK.

Oncol Lett. 2014 Oct;8(4):1613-1617.


An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine.

Maldonado L, Brait M, Michailidi C, Munari E, Driscoll T, Schultz L, Bivalacqua T, Schoenberg M, Sidransky D, Netto GJ, Hoque MO.

Oncotarget. 2014 Jul 30;5(14):5218-33.


Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine.

Hayashi M, Bernert H, Kagohara LT, Maldonado L, Brait M, Schoenberg M, Bivalacqua T, Netto GJ, Koch W, Sidransky D, Hoque MO.

Oncotarget. 2014 May 30;5(10):3350-61.


Long-term use of valproic acid in US veterans is associated with a reduced risk of smoking-related cases of head and neck cancer.

Kang H, Gillespie TW, Goodman M, Brodie SA, Brandes M, Ribeiro M, Ramalingam SS, Shin DM, Khuri FR, Brandes JC.

Cancer. 2014 May 1;120(9):1394-400. doi: 10.1002/cncr.28479.


DNA methylation as clinically useful biomarkers-light at the end of the tunnel.

Levenson VV, Melnikov AA.

Pharmaceuticals (Basel). 2012 Jan 18;5(1):94-113. doi: 10.3390/ph5010094.


Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population.

Brebi P, Maldonado L, Noordhuis MG, Ili C, Leal P, Garcia P, Brait M, Ribas J, Michailidi C, Perez J, Soudry E, Tapia O, Guzman P, Muñoz S, Van Neste L, Van Criekinge W, Irizarry R, Sidransky D, Roa JC, Guerrero-Preston R.

Epigenetics. 2014 Feb;9(2):308-17. doi: 10.4161/epi.27120.


Association of promoter methylation of VGF and PGP9.5 with ovarian cancer progression.

Brait M, Maldonado L, Noordhuis MG, Begum S, Loyo M, Poeta ML, Barbosa A, Fazio VM, Angioli R, Rabitti C, Marchionni L, de Graeff P, van der Zee AG, Wisman GB, Sidransky D, Hoque MO.

PLoS One. 2013 Sep 27;8(9):e70878. doi: 10.1371/journal.pone.0070878. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/ccd51e37-fdf3-466e-b79f-2c390df9ab28. PLoS One. 2013;8(10). doi:10.1371/annotation/5d2e13d4-cb4e-44b1-a836-dff9b4144b5b. Noordhuis, Maartje [corrected to Noordhuis, Maartje G].


Cigarette smoke induces methylation of the tumor suppressor gene NISCH.

Ostrow KL, Michailidi C, Guerrero-Preston R, Hoque MO, Greenberg A, Rom W, Sidransky D.

Epigenetics. 2013 Apr;8(4):383-8. doi: 10.4161/epi.24195.


Prediction of heterogeneous differential genes by detecting outliers to a Gaussian tight cluster.

Yang Z, Yang Z.

BMC Bioinformatics. 2013 Mar 5;14:81. doi: 10.1186/1471-2105-14-81.


Epigenome-Wide Association Studies (EWAS) in Cancer.

Verma M.

Curr Genomics. 2012 Jun;13(4):308-13. doi: 10.2174/138920212800793294.


OGDHL is a modifier of AKT-dependent signaling and NF-κB function.

Sen T, Sen N, Noordhuis MG, Ravi R, Wu TC, Ha PK, Sidransky D, Hoque MO.

PLoS One. 2012;7(11):e48770. doi: 10.1371/journal.pone.0048770.


Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers.

Decock A, Ongenaert M, Hoebeeck J, De Preter K, Van Peer G, Van Criekinge W, Ladenstein R, Schulte JH, Noguera R, Stallings RL, Van Damme A, Laureys G, Vermeulen J, Van Maerken T, Speleman F, Vandesompele J.

Genome Biol. 2012 Oct 3;13(10):R95. doi: 10.1186/gb-2012-13-10-r95.


Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers.

Brait M, Ling S, Nagpal JK, Chang X, Park HL, Lee J, Okamura J, Yamashita K, Sidransky D, Kim MS.

PLoS One. 2012;7(9):e44951. doi: 10.1371/journal.pone.0044951.

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