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Items: 17


Identification of novel potent human testis-specific and bromodomain-containing protein (BRDT) inhibitors using crystal structure-based virtual screening.

Gao N, Ren J, Hou L, Zhou Y, Xin L, Wang J, Yu H, Xie Y, Wang H.

Int J Mol Med. 2016 Jul;38(1):39-44. doi: 10.3892/ijmm.2016.2602.


Women-specific factors to consider in risk, diagnosis and treatment of cardiovascular disease.

Harvey RE, Coffman KE, Miller VM.

Womens Health (Lond). 2015 Mar;11(2):239-57. doi: 10.2217/whe.14.64. Review.


Pharmacological evaluation and antifertility activity of Jatropha gossypifolia in rats.

Jain S, Choudhary GP, Jain DK.

Biomed Res Int. 2013;2013:125980. doi: 10.1155/2013/125980.


Pharmacological activity of retinoic acid receptor alpha-selective antagonists in vitro and in vivo.

Chung SS, Cuellar RA, Wang X, Reczek PR, Georg GI, Wolgemuth DJ.

ACS Med Chem Lett. 2013 May 9;4(5):446-450.


SAS1B protein [ovastacin] shows temporal and spatial restriction to oocytes in several eutherian orders and initiates translation at the primary to secondary follicle transition.

Pires ES, Hlavin C, Macnamara E, Ishola-Gbenla K, Doerwaldt C, Chamberlain C, Klotz K, Herr AK, Khole A, Chertihin O, Curnow E, Feldman SH, Mandal A, Shetty J, Flickinger C, Herr JC.

Dev Dyn. 2013 Dec;242(12):1405-26. doi: 10.1002/dvdy.24040.


RiboTag analysis of actively translated mRNAs in Sertoli and Leydig cells in vivo.

Sanz E, Evanoff R, Quintana A, Evans E, Miller JA, Ko C, Amieux PS, Griswold MD, McKnight GS.

PLoS One. 2013 Jun 11;8(6):e66179. doi: 10.1371/journal.pone.0066179.


Small-molecule inhibition of BRDT for male contraception.

Matzuk MM, McKeown MR, Filippakopoulos P, Li Q, Ma L, Agno JE, Lemieux ME, Picaud S, Yu RN, Qi J, Knapp S, Bradner JE.

Cell. 2012 Aug 17;150(4):673-84.


Cancer/testis (CT) antigens, carcinogenesis and spermatogenesis.

Cheng YH, Wong EW, Cheng CY.

Spermatogenesis. 2011 Jul;1(3):209-220.


The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction.

Dun MD, Smith ND, Baker MA, Lin M, Aitken RJ, Nixon B.

J Biol Chem. 2011 Oct 21;286(42):36875-87. doi: 10.1074/jbc.M110.188888.


Vaginally administered PEGylated LIF antagonist blocked embryo implantation and eliminated non-target effects on bone in mice.

Menkhorst E, Zhang JG, Sims NA, Morgan PO, Soo P, Poulton IJ, Metcalf D, Alexandrou E, Gresle M, Salamonsen LA, Butzkueven H, Nicola NA, Dimitriadis E.

PLoS One. 2011;6(5):e19665. doi: 10.1371/journal.pone.0019665.


Oral administration of a retinoic Acid receptor antagonist reversibly inhibits spermatogenesis in mice.

Chung SS, Wang X, Roberts SS, Griffey SM, Reczek PR, Wolgemuth DJ.

Endocrinology. 2011 Jun;152(6):2492-502. doi: 10.1210/en.2010-0941.


Adjudin, a potential male contraceptive, exerts its effects locally in the seminiferous epithelium of mammalian testes.

Mok KW, Mruk DD, Lie PP, Lui WY, Cheng CY.

Reproduction. 2011 May;141(5):571-80. doi: 10.1530/REP-10-0464. Review.


An in vivo study on adjudin and blood-testis barrier dynamics.

Kopera IA, Su L, Bilinska B, Cheng CY, Mruk DD.

Endocrinology. 2009 Oct;150(10):4724-33. doi: 10.1210/en.2008-1779.


The biology of infertility: research advances and clinical challenges.

Matzuk MM, Lamb DJ.

Nat Med. 2008 Nov;14(11):1197-213. doi: 10.1038/nm.f.1895. Review.


Global health inequity: scientific challenges remain but can be solved.

Dahl CA, Yamada T.

J Clin Invest. 2008 Apr;118(4):1242-3. doi: 10.1172/JCI35396.

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