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Modulating Neurotrophin Receptor Signaling as a Therapeutic Strategy for Huntington's Disease.

Simmons DA.

J Huntingtons Dis. 2017;6(4):303-325. doi: 10.3233/JHD-170275.


Anesthetic Alterations of Collective Terahertz Oscillations in Tubulin Correlate with Clinical Potency: Implications for Anesthetic Action and Post-Operative Cognitive Dysfunction.

Craddock TJA, Kurian P, Preto J, Sahu K, Hameroff SR, Klobukowski M, Tuszynski JA.

Sci Rep. 2017 Aug 29;7(1):9877. doi: 10.1038/s41598-017-09992-7.


Emotional Modulation of Learning and Memory: Pharmacological Implications.

LaLumiere RT, McGaugh JL, McIntyre CK.

Pharmacol Rev. 2017 Jul;69(3):236-255. doi: 10.1124/pr.116.013474. Review.


Potential therapeutic approaches for Angelman syndrome.

Bi X, Sun J, Ji AX, Baudry M.

Expert Opin Ther Targets. 2016;20(5):601-13. doi: 10.1517/14728222.2016.1115837. Epub 2015 Nov 26. Review.


BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome.

Saavedra A, Puigdellívol M, Tyebji S, Kurup P, Xu J, Ginés S, Alberch J, Lombroso PJ, Pérez-Navarro E.

Mol Neurobiol. 2016 Aug;53(6):4261-4273. doi: 10.1007/s12035-015-9335-7. Epub 2015 Jul 30.


UBE3A Regulates Synaptic Plasticity and Learning and Memory by Controlling SK2 Channel Endocytosis.

Sun J, Zhu G, Liu Y, Standley S, Ji A, Tunuguntla R, Wang Y, Claus C, Luo Y, Baudry M, Bi X.

Cell Rep. 2015 Jul 21;12(3):449-61. doi: 10.1016/j.celrep.2015.06.023. Epub 2015 Jul 9.


Neurons and networks organizing and sequencing memories.

Deadwyler SA, Berger TW, Opris I, Song D, Hampson RE.

Brain Res. 2015 Sep 24;1621:335-44. doi: 10.1016/j.brainres.2014.12.037. Epub 2014 Dec 29.


A BDNF loop-domain mimetic acutely reverses spontaneous apneas and respiratory abnormalities during behavioral arousal in a mouse model of Rett syndrome.

Kron M, Lang M, Adams IT, Sceniak M, Longo F, Katz DM.

Dis Model Mech. 2014 Sep;7(9):1047-55. doi: 10.1242/dmm.016030.


Transcriptional and epigenetic regulation of Hebbian and non-Hebbian plasticity.

Guzman-Karlsson MC, Meadows JP, Gavin CF, Hablitz JJ, Sweatt JD.

Neuropharmacology. 2014 May;80:3-17. doi: 10.1016/j.neuropharm.2014.01.001. Epub 2014 Jan 10. Review.


FK506-binding protein 1b/12.6: a key to aging-related hippocampal Ca2+ dysregulation?

Gant JC, Blalock EM, Chen KC, Kadish I, Porter NM, Norris CM, Thibault O, Landfield PW.

Eur J Pharmacol. 2014 Sep 15;739:74-82. doi: 10.1016/j.ejphar.2013.10.070. Epub 2013 Nov 28. Review.


A small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease.

Simmons DA, Belichenko NP, Yang T, Condon C, Monbureau M, Shamloo M, Jing D, Massa SM, Longo FM.

J Neurosci. 2013 Nov 27;33(48):18712-27. doi: 10.1523/JNEUROSCI.1310-13.2013. Erratum in: J Neurosci. 2014 Jan 29;34(5):2012.


NMDA receptor activation and calpain contribute to disruption of dendritic spines by the stress neuropeptide CRH.

Andres AL, Regev L, Phi L, Seese RR, Chen Y, Gall CM, Baram TZ.

J Neurosci. 2013 Oct 23;33(43):16945-60. doi: 10.1523/JNEUROSCI.1445-13.2013.


Oroxylin A Induces BDNF Expression on Cortical Neurons through Adenosine A2A Receptor Stimulation: A Possible Role in Neuroprotection.

Jeon SJ, Bak H, Seo J, Han SM, Lee SH, Han SH, Kwon KJ, Ryu JH, Cheong JH, Ko KH, Yang SI, Choi JW, Park SH, Shin CY.

Biomol Ther (Seoul). 2012 Jan;20(1):27-35. doi: 10.4062/biomolther.2012.20.1.027.


Mechanism based approaches for rescuing and enhancing cognition.

Lynch G, Gall CM.

Front Neurosci. 2013 Aug 15;7:143. doi: 10.3389/fnins.2013.00143. eCollection 2013.


A loss-of-function screen for phosphatases that regulate neurite outgrowth identifies PTPN12 as a negative regulator of TrkB tyrosine phosphorylation.

Ambjørn M, Dubreuil V, Miozzo F, Nigon F, Møller B, Issazadeh-Navikas S, Berg J, Lees M, Sap J.

PLoS One. 2013 Jun 13;8(6):e65371. doi: 10.1371/journal.pone.0065371. Print 2013.


Acute BDNF treatment upregulates GluR1-SAP97 and GluR2-GRIP1 interactions: implications for sustained AMPA receptor expression.

Jourdi H, Kabbaj M.

PLoS One. 2013;8(2):e57124. doi: 10.1371/journal.pone.0057124. Epub 2013 Feb 27.


Progesterone-estrogen interactions in synaptic plasticity and neuroprotection.

Baudry M, Bi X, Aguirre C.

Neuroscience. 2013 Jun 3;239:280-94. doi: 10.1016/j.neuroscience.2012.10.051. Epub 2012 Nov 7. Review.


Estrogen promotes learning-related plasticity by modifying the synaptic cytoskeleton.

Kramár EA, Babayan AH, Gall CM, Lynch G.

Neuroscience. 2013 Jun 3;239:3-16. doi: 10.1016/j.neuroscience.2012.10.038. Epub 2012 Oct 25. Review.


Fragmentation and unpredictability of early-life experience in mental disorders.

Baram TZ, Davis EP, Obenaus A, Sandman CA, Small SL, Solodkin A, Stern H.

Am J Psychiatry. 2012 Sep;169(9):907-15. doi: 10.1176/appi.ajp.2012.11091347. Review.


Differences between synaptic plasticity thresholds result in new timing rules for maximizing long-term potentiation.

Lynch G, Kramár EA, Babayan AH, Rumbaugh G, Gall CM.

Neuropharmacology. 2013 Jan;64:27-36. doi: 10.1016/j.neuropharm.2012.07.006. Epub 2012 Jul 20. Review.

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