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Items: 1 to 20 of 47


Stress and Non-Stress Roles of Inflammatory Signals during HSC Emergence and Maintenance.

Clapes T, Lefkopoulos S, Trompouki E.

Front Immunol. 2016 Nov 7;7:487. Review.


Hematopoietic Stem Cell Regulation by Type I and II Interferons in the Pathogenesis of Acquired Aplastic Anemia.

Smith JN, Kanwar VS, MacNamara KC.

Front Immunol. 2016 Aug 29;7:330. doi: 10.3389/fimmu.2016.00330. Review.


Pathogenesis of Crohn's disease.

Boyapati R, Satsangi J, Ho GT.

F1000Prime Rep. 2015 Apr 2;7:44. doi: 10.12703/P7-44. Review.


Striking the Right Balance Determines TB or Not TB.

BoseDasgupta S, Pieters J.

Front Immunol. 2014 Oct 8;5:455. doi: 10.3389/fimmu.2014.00455. Review.


Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer's disease.

Landel V, Baranger K, Virard I, Loriod B, Khrestchatisky M, Rivera S, Benech P, Féron F.

Mol Neurodegener. 2014 Sep 11;9:33. doi: 10.1186/1750-1326-9-33.


Type II interferon promotes differentiation of myeloid-biased hematopoietic stem cells.

Matatall KA, Shen CC, Challen GA, King KY.

Stem Cells. 2014 Nov;32(11):3023-30. doi: 10.1002/stem.1799.


Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons.

Pietras EM, Lakshminarasimhan R, Techner JM, Fong S, Flach J, Binnewies M, Passegué E.

J Exp Med. 2014 Feb 10;211(2):245-62. doi: 10.1084/jem.20131043.


Nfix is a novel regulator of murine hematopoietic stem and progenitor cell survival.

Holmfeldt P, Pardieck J, Saulsberry AC, Nandakumar SK, Finkelstein D, Gray JT, Persons DA, McKinney-Freeman S.

Blood. 2013 Oct 24;122(17):2987-96. doi: 10.1182/blood-2013-04-493973.


Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation.

Liu B, Gulati AS, Cantillana V, Henry SC, Schmidt EA, Daniell X, Grossniklaus E, Schoenborn AA, Sartor RB, Taylor GA.

Am J Physiol Gastrointest Liver Physiol. 2013 Oct 15;305(8):G573-84. doi: 10.1152/ajpgi.00071.2013.


Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-γ-induced mouse cells.

Springer HM, Schramm M, Taylor GA, Howard JC.

J Immunol. 2013 Aug 15;191(4):1765-74. doi: 10.4049/jimmunol.1300641.


Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery.

Kahle JJ, Souroullas GP, Yu P, Zohren F, Lee Y, Shaw CA, Zoghbi HY, Goodell MA.

PLoS Genet. 2013 Mar;9(3):e1003359. doi: 10.1371/journal.pgen.1003359.


The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18.

Behnke MS, Fentress SJ, Mashayekhi M, Li LX, Taylor GA, Sibley LD.

PLoS Pathog. 2012;8(11):e1002992. doi: 10.1371/journal.ppat.1002992.


Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice.

Rossi L, Lin KK, Boles NC, Yang L, King KY, Jeong M, Mayle A, Goodell MA.

Cell Stem Cell. 2012 Sep 7;11(3):302-17. doi: 10.1016/j.stem.2012.08.006. Review.


Signal transduction pathways, intrinsic regulators, and the control of cell fate choice.

Fossett N.

Biochim Biophys Acta. 2013 Feb;1830(2):2375-84. doi: 10.1016/j.bbagen.2012.06.005. Review.


Noncanonical NF-κB signaling regulates hematopoietic stem cell self-renewal and microenvironment interactions.

Zhao C, Xiu Y, Ashton J, Xing L, Morita Y, Jordan CT, Boyce BF.

Stem Cells. 2012 Apr;30(4):709-18. doi: 10.1002/stem.1050.


Transient activation of hematopoietic stem and progenitor cells by IFNγ during acute bacterial infection.

MacNamara KC, Jones M, Martin O, Winslow GM.

PLoS One. 2011;6(12):e28669. doi: 10.1371/journal.pone.0028669.


Dnmt3a is essential for hematopoietic stem cell differentiation.

Challen GA, Sun D, Jeong M, Luo M, Jelinek J, Berg JS, Bock C, Vasanthakumar A, Gu H, Xi Y, Liang S, Lu Y, Darlington GJ, Meissner A, Issa JP, Godley LA, Li W, Goodell MA.

Nat Genet. 2011 Dec 4;44(1):23-31. doi: 10.1038/ng.1009.


Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells.

Berg JS, Lin KK, Sonnet C, Boles NC, Weksberg DC, Nguyen H, Holt LJ, Rickwood D, Daly RJ, Goodell MA.

PLoS One. 2011;6(10):e26410. doi: 10.1371/journal.pone.0026410.


CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway.

Lin KK, Rossi L, Boles NC, Hall BE, George TC, Goodell MA.

PLoS Biol. 2011 Sep;9(9):e1001148. doi: 10.1371/journal.pbio.1001148.

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