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Items: 1 to 20 of 236


Advances in the delivery of RNA therapeutics: from concept to clinical reality.

Kaczmarek JC, Kowalski PS, Anderson DG.

Genome Med. 2017 Jun 27;9(1):60. doi: 10.1186/s13073-017-0450-0. Review.


A Novel Single-Strand RNAi Therapeutic Agent Targeting the (Pro)renin Receptor Suppresses Ocular Inflammation.

Kanda A, Ishizuka ET, Shibata A, Matsumoto T, Toyofuku H, Noda K, Namba K, Ishida S.

Mol Ther Nucleic Acids. 2017 Jun 16;7:116-126. doi: 10.1016/j.omtn.2017.01.001. Epub 2017 Jan 12.


Differential Induction of Immunogenic Cell Death and Interferon Expression in Cancer Cells by Structured ssRNAs.

Lee J, Lee Y, Xu L, White R, Sullenger BA.

Mol Ther. 2017 Jun 7;25(6):1295-1305. doi: 10.1016/j.ymthe.2017.03.014. Epub 2017 Mar 31.


Therapeutic Effect of Novel Single-Stranded RNAi Agent Targeting Periostin in Eyes with Retinal Neovascularization.

Nakama T, Yoshida S, Ishikawa K, Kubo Y, Kobayashi Y, Zhou Y, Nakao S, Hisatomi T, Ikeda Y, Takao K, Yoshikawa K, Matsuda A, Ono J, Ohta S, Izuhara K, Kudo A, Sonoda KH, Ishibashi T.

Mol Ther Nucleic Acids. 2017 Mar 17;6:279-289. doi: 10.1016/j.omtn.2017.01.004. Epub 2017 Feb 9.


Human CD64-targeted non-viral siRNA delivery system for blood monocyte gene modulation.

Yong SB, Kim HJ, Kim JK, Chung JY, Kim YH.

Sci Rep. 2017 Feb 7;7:42171. doi: 10.1038/srep42171.


High Interleukin-12 Levels May Prevent an Increase in the Amount of Fungi in the Gastrointestinal Tract during the First Years of Diabetes Mellitus Type 1.

Kowalewska B, Zorena K, Szmigiero-Kawko M, Wąż P, Myśliwiec M.

Dis Markers. 2016;2016:4685976. doi: 10.1155/2016/4685976. Epub 2016 Dec 29.


Interplay of extracellular matrix and leukocytes in lung inflammation.

Wight TN, Frevert CW, Debley JS, Reeves SR, Parks WC, Ziegler SF.

Cell Immunol. 2017 Feb;312:1-14. doi: 10.1016/j.cellimm.2016.12.003. Epub 2016 Dec 23. Review.


Evaluating side effects of nanoparticle-mediated siRNA delivery to mesenchymal stem cells using next generation sequencing and enrichment analysis.

Malcolm DW, Sorrells JE, Van Twisk D, Thakar J, Benoit DS.

Bioeng Transl Med. 2016 Jun;1(2):193-206. Epub 2016 Oct 24.


Off Target, but Sequence-Specific, shRNA-Associated Trans-Activation of Promoter Reporters in Transient Transfection Assays.

Masuda T, Wan J, Yerrabelli A, Berlinicke C, Kallman A, Qian J, Zack DJ.

PLoS One. 2016 Dec 15;11(12):e0167867. doi: 10.1371/journal.pone.0167867. eCollection 2016.


Intramyocardial Injection of siRNAs Can Efficiently Establish Myocardial Tissue-Specific Renalase Knockdown Mouse Model.

Huang K, Liu J, Zhang H, Wang J, Li H.

Biomed Res Int. 2016;2016:1267570. Epub 2016 Oct 27.


The role of Toll-like receptors in retinal ischemic diseases.

Xu WQ, Wang YS.

Int J Ophthalmol. 2016 Sep 18;9(9):1343-51. doi: 10.18240/ijo.2016.09.19. eCollection 2016. Review.


Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi-peptide nanoparticles to tumour-associated macrophages and cancer cells.

Conde J, Bao C, Tan Y, Cui D, Edelman ER, Azevedo HS, Byrne HJ, Artzi N, Tian F.

Adv Funct Mater. 2015 Jul 15;25(27):4183-4194. Epub 2015 Jun 1.


Interleukin-12 inhibits pathological neovascularization in mouse model of oxygen-induced retinopathy.

Zhou Y, Yoshida S, Kubo Y, Kobayashi Y, Nakama T, Yamaguchi M, Ishikawa K, Nakao S, Ikeda Y, Ishibashi T, Sonoda KH.

Sci Rep. 2016 Jun 17;6:28140. doi: 10.1038/srep28140.


Delivery strategies and potential targets for siRNA in major cancer types.

Lee SJ, Kim MJ, Kwon IC, Roberts TM.

Adv Drug Deliv Rev. 2016 Sep 1;104:2-15. doi: 10.1016/j.addr.2016.05.010. Epub 2016 May 31. Review.


Strand and Cell Type-specific Function of microRNA-126 in Angiogenesis.

Zhou Q, Anderson C, Hanus J, Zhao F, Ma J, Yoshimura A, Wang S.

Mol Ther. 2016 Oct;24(10):1823-1835. doi: 10.1038/mt.2016.108. Epub 2016 May 19.


Plant microRNAs as novel immunomodulatory agents.

Cavalieri D, Rizzetto L, Tocci N, Rivero D, Asquini E, Si-Ammour A, Bonechi E, Ballerini C, Viola R.

Sci Rep. 2016 May 11;6:25761. doi: 10.1038/srep25761.


Topical Use of Angiopoietin-like Protein 2 RNAi-loaded Lipid Nanoparticles Suppresses Corneal Neovascularization.

Taketani Y, Usui T, Toyono T, Shima N, Yokoo S, Kimakura M, Yamagami S, Ohno S, Onodera R, Tahara K, Takeuchi H, Kuroda M.

Mol Ther Nucleic Acids. 2016 Mar 8;5:e292. doi: 10.1038/mtna.2016.1.


Development of Novel Small Hairpin RNAs That do not Require Processing by Dicer or AGO2.

Ohno S, Itano K, Harada Y, Asada K, Oikawa K, Kashiwazako M, Okuyama H, Kumagai K, Takanashi M, Sudo K, Ikeda N, Kuroda M.

Mol Ther. 2016 Aug;24(7):1278-89. doi: 10.1038/mt.2016.81. Epub 2016 Apr 25.


Efficacy of rintatolimod in the treatment of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME).

Mitchell WM.

Expert Rev Clin Pharmacol. 2016 Jun;9(6):755-70. doi: 10.1586/17512433.2016.1172960. Review.


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