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Comparative Study of Transcriptome Profiles of Mouse Livers and Skins Infected by Fork-Tailed or Non-Fork-Tailed Schistosoma japonicum.

Yang Y, He JJ, Hu S, Chang H, Xiang X, Yang JF, Zou FC.

Front Microbiol. 2017 Aug 30;8:1648. doi: 10.3389/fmicb.2017.01648. eCollection 2017.


Nitric oxide blocks the development of the human parasite Schistosoma japonicum.

Shen J, Lai DH, Wilson RA, Chen YF, Wang LF, Yu ZL, Li MY, He P, Hide G, Sun X, Yang TB, Wu ZD, Ayala FJ, Lun ZR.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10214-10219. doi: 10.1073/pnas.1708578114. Epub 2017 Sep 5.


The Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I).

Salinas G, Gao W, Wang Y, Bonilla M, Yu L, Novikov A, Virginio VG, Ferreira HB, Vieites M, Gladyshev VN, Gambino D, Dai S.

Antioxid Redox Signal. 2017 Dec 20;27(18):1491-1504. doi: 10.1089/ars.2016.6816. Epub 2017 Jun 26.


Sexual Preferences in Nutrient Utilization Regulate Oxygen Consumption and Reactive Oxygen Species Generation in Schistosoma mansoni: Potential Implications for Parasite Redox Biology.

Oliveira MP, Correa Soares JB, Oliveira MF.

PLoS One. 2016 Jul 5;11(7):e0158429. doi: 10.1371/journal.pone.0158429. eCollection 2016.


QSAR-Driven Discovery of Novel Chemical Scaffolds Active against Schistosoma mansoni.

Melo-Filho CC, Dantas RF, Braga RC, Neves BJ, Senger MR, Valente WC, Rezende-Neto JM, Chaves WT, Muratov EN, Paveley RA, Furnham N, Kamentsky L, Carpenter AE, Silva-Junior FP, Andrade CH.

J Chem Inf Model. 2016 Jul 25;56(7):1357-72. doi: 10.1021/acs.jcim.6b00055. Epub 2016 Jun 16.



Mendonça AM, Feitosa AP, Veras DL, Matos-Rocha TJ, Cavalcanti MG, Barbosa CC, Brayner FA, Alves LC.

Rev Inst Med Trop Sao Paulo. 2016;58:7. doi: 10.1590/S1678-9946201658007. Epub 2016 Feb 23.


Oxadiazole-2-oxides may have other functional targets, in addition to SjTGR, through which they cause mortality in Schistosoma japonicum.

Song LJ, Luo H, Fan WH, Wang GP, Yin XR, Shen S, Wang J, Jin Y, Zhang W, Gao H, Liu Q, Wang WL, Feng B, Yu CX.

Parasit Vectors. 2016 Jan 20;9:26. doi: 10.1186/s13071-016-1301-3.


High-throughput screening against thioredoxin glutathione reductase identifies novel inhibitors with potential therapeutic value for schistosomiasis.

Li T, Ziniel PD, He PQ, Kommer VP, Crowther GJ, He M, Liu Q, Van Voorhis WC, Williams DL, Wang MW.

Infect Dis Poverty. 2015 Aug 31;4:40. doi: 10.1186/s40249-015-0071-z.


Comparative Analysis of Transcriptional Profiles of Adult Schistosoma japonicum from Different Laboratory Animals and the Natural Host, Water Buffalo.

Liu S, Zhou X, Piao X, Wu C, Hou N, Chen Q.

PLoS Negl Trop Dis. 2015 Aug 18;9(8):e0003993. doi: 10.1371/journal.pntd.0003993. eCollection 2015 Aug.


Molecular docking to explore the possible binding mode of potential inhibitors of thioredoxin glutathione reductase.

Huang J, Hua W, Li J, Hua Z.

Mol Med Rep. 2015 Oct;12(4):5787-95. doi: 10.3892/mmr.2015.4119. Epub 2015 Jul 27.


Application of RNAi to Genomic Drug Target Validation in Schistosomes.

Guidi A, Mansour NR, Paveley RA, Carruthers IM, Besnard J, Hopkins AL, Gilbert IH, Bickle QD.

PLoS Negl Trop Dis. 2015 May 20;9(5):e0003801. doi: 10.1371/journal.pntd.0003801. eCollection 2015 May.


The diterpenoid 7-keto-sempervirol, derived from Lycium chinense, displays anthelmintic activity against both Schistosoma mansoni and Fasciola hepatica.

Edwards J, Brown M, Peak E, Bartholomew B, Nash RJ, Hoffmann KF.

PLoS Negl Trop Dis. 2015 Mar 13;9(3):e0003604. doi: 10.1371/journal.pntd.0003604. eCollection 2015 Mar.


Novel therapeutic and prevention approaches for schistosomiasis: review.

El Ridi RA, Tallima HA.

J Adv Res. 2013 Sep;4(5):467-78. doi: 10.1016/j.jare.2012.05.002. Epub 2012 Jun 23. Review.


An artemisinin derivative of praziquantel as an orally active antischistosomal agent.

Dong L, Duan W, Chen J, Sun H, Qiao C, Xia CM.

PLoS One. 2014 Nov 11;9(11):e112163. doi: 10.1371/journal.pone.0112163. eCollection 2014.


Epigenetic control of gene function in schistosomes: a source of therapeutic targets?

Cabezas-Cruz A, Lancelot J, Caby S, Oliveira G, Pierce RJ.

Front Genet. 2014 Sep 10;5:317. doi: 10.3389/fgene.2014.00317. eCollection 2014. Review.


New praziquantel derivatives containing NO-donor furoxans and related furazans as active agents against Schistosoma mansoni.

Guglielmo S, Cortese D, Vottero F, Rolando B, Kommer VP, Williams DL, Fruttero R, Gasco A.

Eur J Med Chem. 2014 Sep 12;84:135-45. doi: 10.1016/j.ejmech.2014.07.007. Epub 2014 Jul 3.


Parasite neuropeptide biology: Seeding rational drug target selection?

McVeigh P, Atkinson L, Marks NJ, Mousley A, Dalzell JJ, Sluder A, Hammerland L, Maule AG.

Int J Parasitol Drugs Drug Resist. 2011 Nov 15;2:76-91. doi: 10.1016/j.ijpddr.2011.10.004. eCollection 2012 Dec. Review.


Orally active antischistosomal early leads identified from the open access malaria box.

Ingram-Sieber K, Cowan N, Panic G, Vargas M, Mansour NR, Bickle QD, Wells TN, Spangenberg T, Keiser J.

PLoS Negl Trop Dis. 2014 Jan 9;8(1):e2610. doi: 10.1371/journal.pntd.0002610. eCollection 2014.


Phytol, a diterpene alcohol from chlorophyll, as a drug against neglected tropical disease Schistosomiasis mansoni.

de Moraes J, de Oliveira RN, Costa JP, Junior AL, de Sousa DP, Freitas RM, Allegretti SM, Pinto PL.

PLoS Negl Trop Dis. 2014 Jan 2;8(1):e2617. doi: 10.1371/journal.pntd.0002617. eCollection 2014.


Aldose reductase from Schistosoma japonicum: crystallization and structure-based inhibitor screening for discovering antischistosomal lead compounds.

Liu J, Dyer DH, Cheng J, Wang J, Wang S, Yang Z, Wang X, Hu W.

Parasit Vectors. 2013 Jun 5;6:162. doi: 10.1186/1756-3305-6-162.

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