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Epigenetics: Linking Nutrition to Molecular Mechanisms in Aging.

Park JH, Yoo Y, Park YJ.

Prev Nutr Food Sci. 2017 Jun;22(2):81-89. doi: 10.3746/pnf.2017.22.2.81. Epub 2017 Jun 30. Review.


Cardioprotective Effects of SIRT6 in a Mouse Model of Transverse Aortic Constriction-Induced Heart Failure.

Li Y, Meng X, Wang W, Liu F, Hao Z, Yang Y, Zhao J, Yin W, Xu L, Zhao R, Hu J.

Front Physiol. 2017 Jun 13;8:394. doi: 10.3389/fphys.2017.00394. eCollection 2017.


Sirt6 alters adult hippocampal neurogenesis.

Okun E, Marton D, Cohen D, Griffioen K, Kanfi Y, Illouz T, Madar R, Cohen HY.

PLoS One. 2017 Jun 23;12(6):e0179681. doi: 10.1371/journal.pone.0179681. eCollection 2017.


Is SIRT6 Activity Neuroprotective and How Does It Differ from SIRT1 in This Regard?

Tang BL.

Front Cell Neurosci. 2017 Jun 8;11:165. doi: 10.3389/fncel.2017.00165. eCollection 2017. No abstract available.


NAD+ loss, a new player in AhR biology: prevention of thymus atrophy and hepatosteatosis by NAD+ repletion.

Diani-Moore S, Shoots J, Singh R, Zuk JB, Rifkind AB.

Sci Rep. 2017 May 23;7(1):2268. doi: 10.1038/s41598-017-02332-9.


Sirtuin E is a fungal global transcriptional regulator that determines the transition from the primary growth to the stationary phase.

Itoh E, Odakura R, Oinuma KI, Shimizu M, Masuo S, Takaya N.

J Biol Chem. 2017 Jun 30;292(26):11043-11054. doi: 10.1074/jbc.M116.753772. Epub 2017 May 2.


Characterization of physiological defects in adult SIRT6-/- mice.

Peshti V, Obolensky A, Nahum L, Kanfi Y, Rathaus M, Avraham M, Tinman S, Alt FW, Banin E, Cohen HY.

PLoS One. 2017 Apr 27;12(4):e0176371. doi: 10.1371/journal.pone.0176371. eCollection 2017.


SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation.

Zhang X, Spiegelman NA, Nelson OD, Jing H, Lin H.

Elife. 2017 Apr 13;6. pii: e25158. doi: 10.7554/eLife.25158.


SIRT6 polymorphism rs117385980 is associated with longevity and healthy aging in Finnish men.

Hirvonen K, Laivuori H, Lahti J, Strandberg T, Eriksson JG, Hackman P.

BMC Med Genet. 2017 Apr 11;18(1):41. doi: 10.1186/s12881-017-0401-z.


Fabp4-Cre-mediated Sirt6 deletion impairs adipose tissue function and metabolic homeostasis in mice.

Xiong X, Zhang C, Zhang Y, Fan R, Qian X, Dong XC.

J Endocrinol. 2017 Jun;233(3):307-314. doi: 10.1530/JOE-17-0033. Epub 2017 Apr 6.


SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.

Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD.

Cell Metab. 2017 Apr 4;25(4):838-855.e15. doi: 10.1016/j.cmet.2017.03.003.


Sirt6 deficiency results in progression of glomerular injury in the kidney.

Huang W, Liu H, Zhu S, Woodson M, Liu R, Tilton RG, Miller JD, Zhang W.

Aging (Albany NY). 2017 Mar 28;9(3):1069-1083. doi: 10.18632/aging.101214.


Identification of Predictive DNA Methylation Biomarkers for Chemotherapy Response in Colorectal Cancer.

Baharudin R, Ab Mutalib NS, Othman SN, Sagap I, Rose IM, Mohd Mokhtar N, Jamal R.

Front Pharmacol. 2017 Feb 13;8:47. doi: 10.3389/fphar.2017.00047. eCollection 2017.


The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression.

Gonzalez-Vasconcellos I, Schneider R, Anastasov N, Alonso-Rodriguez S, Sanli-Bonazzi B, Fernández JL, Atkinson MJ.

Sci Rep. 2017 Feb 7;7:42056. doi: 10.1038/srep42056.


Cosmeceutical product consisting of biomimetic peptides: antiaging effects in vivo and in vitro.

Gazitaeva ZI, Drobintseva AO, Chung Y, Polyakova VO, Kvetnoy IM.

Clin Cosmet Investig Dermatol. 2017 Jan 7;10:11-16. doi: 10.2147/CCID.S97573. eCollection 2017.


SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.

Rizzo A, Iachettini S, Salvati E, Zizza P, Maresca C, D'Angelo C, Benarroch-Popivker D, Capolupo A, Del Gaudio F, Cosconati S, Di Maro S, Merlino F, Novellino E, Amoreo CA, Mottolese M, Sperduti I, Gilson E, Biroccio A.

Nucleic Acids Res. 2017 Feb 28;45(4):1820-1834. doi: 10.1093/nar/gkw1202.


Sirtuins in metabolism, DNA repair and cancer.

Mei Z, Zhang X, Yi J, Huang J, He J, Tao Y.

J Exp Clin Cancer Res. 2016 Dec 5;35(1):182. Review.


LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56.

Jain AK, Xi Y, McCarthy R, Allton K, Akdemir KC, Patel LR, Aronow B, Lin C, Li W, Yang L, Barton MC.

Mol Cell. 2016 Dec 1;64(5):967-981. doi: 10.1016/j.molcel.2016.10.039.


Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders.

Jęśko H, Wencel P, Strosznajder RP, Strosznajder JB.

Neurochem Res. 2017 Mar;42(3):876-890. doi: 10.1007/s11064-016-2110-y. Epub 2016 Nov 24. Review.

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