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Items: 16


SH3 domains: modules of protein-protein interactions.

Kurochkina N, Guha U.

Biophys Rev. 2013 Mar;5(1):29-39. doi: 10.1007/s12551-012-0081-z. Epub 2012 Jun 20. Review.


Reciprocal regulation of Abl kinase by Crk Y251 and Abi1 controls invasive phenotypes in glioblastoma.

Kumar S, Lu B, Dixit U, Hossain S, Liu Y, Li J, Hornbeck P, Zheng W, Sowalsky AG, Kotula L, Birge RB.

Oncotarget. 2015 Nov 10;6(35):37792-807. doi: 10.18632/oncotarget.6096.


The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.

Sekino S, Kashiwagi Y, Kanazawa H, Takada K, Baba T, Sato S, Inoue H, Kojima M, Tani K.

Cell Commun Signal. 2015 Oct 1;13:41. doi: 10.1186/s12964-015-0119-5.


Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice.

Xiong X, Chorzalska A, Dubielecka PM, White JR, Vedvyas Y, Hedvat CV, Haimovitz-Friedman A, Koutcher JA, Reimand J, Bader GD, Sawicki JA, Kotula L.

Oncogenesis. 2012 Sep 3;1:e26. doi: 10.1038/oncsis.2012.28.


Structure and dynamic regulation of Abl kinases.

Panjarian S, Iacob RE, Chen S, Engen JR, Smithgall TE.

J Biol Chem. 2013 Feb 22;288(8):5443-50. doi: 10.1074/jbc.R112.438382. Epub 2013 Jan 11. Review.


Crk and ABI1: binary molecular switches that regulate abl tyrosine kinase and signaling to the cytoskeleton.

Hossain S, Dubielecka PM, Sikorski AF, Birge RB, Kotula L.

Genes Cancer. 2012 May;3(5-6):402-13. doi: 10.1177/1947601912460051.


Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.

Sato M, Maruoka M, Takeya T.

J Signal Transduct. 2012;2012:414913. doi: 10.1155/2012/414913. Epub 2012 May 17.


Abi1, a critical molecule coordinating actin cytoskeleton reorganization with PI-3 kinase and growth signaling.

Kotula L.

FEBS Lett. 2012 Aug 14;586(17):2790-4. doi: 10.1016/j.febslet.2012.05.015. Epub 2012 May 19. Review.


Phosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivation.

Sriram G, Reichman C, Tunceroglu A, Kaushal N, Saleh T, Machida K, Mayer B, Ge Q, Li J, Hornbeck P, Kalodimos CG, Birge RB.

Oncogene. 2011 Nov 17;30(46):4645-55. doi: 10.1038/onc.2011.170. Epub 2011 May 23.


Essential role for Abi1 in embryonic survival and WAVE2 complex integrity.

Dubielecka PM, Ladwein KI, Xiong X, Migeotte I, Chorzalska A, Anderson KV, Sawicki JA, Rottner K, Stradal TE, Kotula L.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7022-7. doi: 10.1073/pnas.1016811108. Epub 2011 Apr 11.


ABL tyrosine kinases: evolution of function, regulation, and specificity.

Colicelli J.

Sci Signal. 2010 Sep 14;3(139):re6. doi: 10.1126/scisignal.3139re6. Review. Erratum in: Sci Signal. 2011 Aug 30;4(188):er4.


Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.

Dubielecka PM, Machida K, Xiong X, Hossain S, Ogiue-Ikeda M, Carrera AC, Mayer BJ, Kotula L.

FEBS Lett. 2010 Aug 4;584(15):3279-86. doi: 10.1016/j.febslet.2010.06.029. Epub 2010 Jun 23.


Differential regulation of macropinocytosis by Abi1/Hssh3bp1 isoforms.

Dubielecka PM, Cui P, Xiong X, Hossain S, Heck S, Angelov L, Kotula L.

PLoS One. 2010 May 10;5(5):e10430. doi: 10.1371/journal.pone.0010430.


Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts.

Bradley WD, Koleske AJ.

J Cell Sci. 2009 Oct 1;122(Pt 19):3441-54. doi: 10.1242/jcs.039859.


Enhancement of ABL kinase catalytic efficiency by a direct binding regulator is independent of other regulatory mechanisms.

Cao X, Tanis KQ, Koleske AJ, Colicelli J.

J Biol Chem. 2008 Nov 14;283(46):31401-7. doi: 10.1074/jbc.M804002200. Epub 2008 Sep 16.


Tyrosine phosphorylation in the SH3 domain disrupts negative regulatory interactions within the c-Abl kinase core.

Chen S, O'Reilly LP, Smithgall TE, Engen JR.

J Mol Biol. 2008 Nov 7;383(2):414-23. doi: 10.1016/j.jmb.2008.08.040. Epub 2008 Aug 23.

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