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Large-scale interaction effects reveal missing heritability in schizophrenia, bipolar disorder and posttraumatic stress disorder.

Woo HJ, Yu C, Kumar K, Reifman J.

Transl Psychiatry. 2017 Apr 11;7(4):e1089. doi: 10.1038/tp.2017.61.


Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety: protocol for a systematic review and meta-analysis.

Houghton KT, Forrest A, Awad A, Atkinson LZ, Stockton S, Harrison PJ, Geddes JR, Cipriani A.

BMJ Open. 2017 Mar 27;7(3):e013433. doi: 10.1136/bmjopen-2016-013433.


Reduced levels of Cacna1c attenuate mesolimbic dopamine system function.

Terrillion CE, Dao DT, Cachope R, Lobo MK, Puche AC, Cheer JF, Gould TD.

Genes Brain Behav. 2017 Jun;16(5):495-505. doi: 10.1111/gbb.12371. Epub 2017 Mar 13.


Identification of rare nonsynonymous variants in SYNE1/CPG2 in bipolar affective disorder.

Sharp SI, Lange J, Kandaswamy R, Daher M, Anjorin A, Bass NJ, McQuillin A.

Psychiatr Genet. 2017 Jun;27(3):81-88. doi: 10.1097/YPG.0000000000000166.


Decreased Nucleus Accumbens Expression of Psychiatric Disorder Risk Gene Cacna1c Promotes Susceptibility to Social Stress.

Terrillion CE, Francis TC, Puche AC, Lobo MK, Gould TD.

Int J Neuropsychopharmacol. 2017 May 1;20(5):428-433. doi: 10.1093/ijnp/pyw112.


Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits.

Lane JM, Liang J, Vlasac I, Anderson SG, Bechtold DA, Bowden J, Emsley R, Gill S, Little MA, Luik AI, Loudon A, Scheer FA, Purcell SM, Kyle SD, Lawlor DA, Zhu X, Redline S, Ray DW, Rutter MK, Saxena R.

Nat Genet. 2017 Feb;49(2):274-281. doi: 10.1038/ng.3749. Epub 2016 Dec 19.


Deletion of the Mouse Homolog of CACNA1C Disrupts Discrete Forms of Hippocampal-Dependent Memory and Neurogenesis within the Dentate Gyrus.

Temme SJ, Bell RZ, Fisher GL, Murphy GG.

eNeuro. 2016 Nov 28;3(6). pii: ENEURO.0118-16.2016. eCollection 2016 Nov-Dec.


Genetic variation in the miR-708 gene and its binding targets in bipolar disorder.

Fiorentino A, O'Brien NL, Sharp SI, Curtis D, Bass NJ, McQuillin A.

Bipolar Disord. 2016 Dec;18(8):650-656. doi: 10.1111/bdi.12448. Epub 2016 Nov 16.


Association of ATP6V1B2 rs1106634 with lifetime risk of depression and hippocampal neurocognitive deficits: possible novel mechanisms in the etiopathology of depression.

Gonda X, Eszlari N, Anderson IM, Deakin JF, Bagdy G, Juhasz G.

Transl Psychiatry. 2016 Nov 8;6(11):e945. doi: 10.1038/tp.2016.221.


Monotherapy With Major Antihypertensive Drug Classes and Risk of Hospital Admissions for Mood Disorders.

Boal AH, Smith DJ, McCallum L, Muir S, Touyz RM, Dominiczak AF, Padmanabhan S.

Hypertension. 2016 Nov;68(5):1132-1138. Epub 2016 Oct 10.


Genetic Background Limits Generalizability of Genotype-Phenotype Relationships.

Sittig LJ, Carbonetto P, Engel KA, Krauss KS, Barrios-Camacho CM, Palmer AA.

Neuron. 2016 Sep 21;91(6):1253-9. doi: 10.1016/j.neuron.2016.08.013. Epub 2016 Sep 8.


Diacylglycerol Kinases as Emerging Potential Drug Targets for a Variety of Diseases: An Update.

Sakane F, Mizuno S, Komenoi S.

Front Cell Dev Biol. 2016 Aug 17;4:82. doi: 10.3389/fcell.2016.00082. eCollection 2016. Review.


Genetic Studies on the Tripartite Glutamate Synapse in the Pathophysiology and Therapeutics of Mood Disorders.

de Sousa RT, Loch AA, Carvalho AF, Brunoni AR, Haddad MR, Henter ID, Zarate CA, Machado-Vieira R.

Neuropsychopharmacology. 2017 Mar;42(4):787-800. doi: 10.1038/npp.2016.149. Epub 2016 Aug 11. Review.


A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, Vermeire S, Weersma RK, Halfvarson J, Paavola-Sakki P, Lappalainen M, Lek M, Cummings B, Tukiainen T, Haritunians T, Halme L, Koskinen LL, Ananthakrishnan AN, Luo Y, Heap GA, Visschedijk MC; UK IBD Genetics Consortium; NIDDK IBD Genetics Consortium, MacArthur DG, Neale BM, Ahmad T, Anderson CA, Brant SR, Duerr RH, Silverberg MS, Cho JH, Palotie A, Saavalainen P, Kontula K, Färkkilä M, McGovern DP, Franke A, Stefansson K, Rioux JD, Xavier RJ, Daly MJ, Barrett J, de Lane K, Edwards C, Hart A, Hawkey C, Jostins L, Kennedy N, Lamb C, Lee J, Lees C, Mansfield J, Mathew C, Mowatt C, Newman B, Nimmo E, Parkes M, Pollard M, Prescott N, Randall J, Rice D, Satsangi J, Simmons A, Tremelling M, Uhlig H, Wilson D, Abraham C, Achkar JP, Bitton A, Boucher G, Croitoru K, Fleshner P, Glas J, Kugathasan S, Limbergen JV, Milgrom R, Proctor D, Regueiro M, Schumm PL, Sharma Y, Stempak JM, Targan SR, Wang MH.

Nat Commun. 2016 Aug 9;7:12342. doi: 10.1038/ncomms12342.


Identification of Susceptible Loci and Enriched Pathways for Bipolar II Disorder Using Genome-Wide Association Studies.

Kao CF, Chen HW, Chen HC, Yang JH, Huang MC, Chiu YH, Lin SK, Lee YC, Liu CM, Chuang LC, Chen CH, Wu JY, Lu RB, Kuo PH.

Int J Neuropsychopharmacol. 2016 Dec 3;19(12). pii: pyw064. doi: 10.1093/ijnp/pyw064. Print 2016 Dec.


Overview of the Genetics of Alcohol Use Disorder.

Tawa EA, Hall SD, Lohoff FW.

Alcohol Alcohol. 2016 Sep;51(5):507-14. doi: 10.1093/alcalc/agw046. Epub 2016 Jul 21. Review.


Mitochondrial Oxidative Phosphorylation System (OXPHOS) Deficits in Schizophrenia: Possible Interactions with Cellular Processes.

Bergman O, Ben-Shachar D.

Can J Psychiatry. 2016 Aug;61(8):457-69. doi: 10.1177/0706743716648290.


CACNA1C hypermethylation is associated with bipolar disorder.

Starnawska A, Demontis D, Pen A, Hedemand A, Nielsen AL, Staunstrup NH, Grove J, Als TD, Jarram A, O'Brien NL, Mors O, McQuillin A, Børglum AD, Nyegaard M.

Transl Psychiatry. 2016 Jun 7;6(6):e831. doi: 10.1038/tp.2016.99.


Variable Selection with Prior Information for Generalized Linear Models via the Prior LASSO Method.

Jiang Y, He Y, Zhang H.

J Am Stat Assoc. 2016;111(513):355-376. Epub 2016 May 5.

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