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Items: 1 to 20 of 131


Hypermutation signature reveals a slippage and realignment model of translesion synthesis by Rev3 polymerase in cisplatin-treated yeast.

Segovia R, Shen Y, Lujan SA, Jones SJ, Stirling PC.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2663-2668. doi: 10.1073/pnas.1618555114. Epub 2017 Feb 21.


Predictability of Genetic Interactions from Functional Gene Modules.

Young JH, Marcotte EM.

G3 (Bethesda). 2017 Feb 9;7(2):617-624. doi: 10.1534/g3.116.035915.


Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development.

Iwanami N, Sikora K, Richter AS, Mönnich M, Guerri L, Soza-Ried C, Lawir DF, Mateos F, Hess I, O'Meara CP, Schorpp M, Boehm T.

Cell Rep. 2016 Nov 22;17(9):2259-2270. doi: 10.1016/j.celrep.2016.11.003.


Systematic chemical-genetic and chemical-chemical interaction datasets for prediction of compound synergism.

Wildenhain J, Spitzer M, Dolma S, Jarvik N, White R, Roy M, Griffiths E, Bellows DS, Wright GD, Tyers M.

Sci Data. 2016 Nov 22;3:160095. doi: 10.1038/sdata.2016.95.


Modifiers of the Genotype-Phenotype Map: Hsp90 and Beyond.

Schell R, Mullis M, Ehrenreich IM.

PLoS Biol. 2016 Nov 10;14(11):e2001015. doi: 10.1371/journal.pbio.2001015. eCollection 2016 Nov.


iSeq: A New Double-Barcode Method for Detecting Dynamic Genetic Interactions in Yeast.

Jaffe M, Sherlock G, Levy SF.

G3 (Bethesda). 2017 Jan 5;7(1):143-153. doi: 10.1534/g3.116.034207.


Signal-Oriented Pathway Analyses Reveal a Signaling Complex as a Synthetic Lethal Target for p53 Mutations.

Lu S, Cai C, Yan G, Zhou Z, Wan Y, Chen V, Chen L, Cooper GF, Obeid LM, Hannun YA, Lee AV, Lu X.

Cancer Res. 2016 Dec 1;76(23):6785-6794. Epub 2016 Oct 10.


Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma.

Chang JG, Chen CC, Wu YY, Che TF, Huang YS, Yeh KT, Shieh GS, Yang PC.

Oncotarget. 2016 Nov 8;7(45):73664-73680. doi: 10.18632/oncotarget.12046.


Dosage Mutator Genes in Saccharomyces cerevisiae: A Novel Mutator Mode-of-Action of the Mph1 DNA Helicase.

Ang JS, Duffy S, Segovia R, Stirling PC, Hieter P.

Genetics. 2016 Nov;204(3):975-986. doi: 10.1534/genetics.116.192211. Epub 2016 Aug 31.


The Deubiquitinase USP47 Stabilizes MAPK by Counteracting the Function of the N-end Rule ligase POE/UBR4 in Drosophila.

Ashton-Beaucage D, Lemieux C, Udell CM, Sahmi M, Rochette S, Therrien M.

PLoS Biol. 2016 Aug 23;14(8):e1002539. doi: 10.1371/journal.pbio.1002539. eCollection 2016 Aug.


Overexpression screens identify conserved dosage chromosome instability genes in yeast and human cancer.

Duffy S, Fam HK, Wang YK, Styles EB, Kim JH, Ang JS, Singh T, Larionov V, Shah SP, Andrews B, Boerkoel CF, Hieter P.

Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):9967-76. doi: 10.1073/pnas.1611839113. Epub 2016 Aug 22.


Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress.

O'Meara TR, Veri AO, Polvi EJ, Li X, Valaei SF, Diezmann S, Cowen LE.

PLoS Genet. 2016 Jun 24;12(6):e1006142. doi: 10.1371/journal.pgen.1006142. eCollection 2016 Jun.


Combinatorial strategies for combating invasive fungal infections.

Spitzer M, Robbins N, Wright GD.

Virulence. 2017 Feb 17;8(2):169-185. doi: 10.1080/21505594.2016.1196300. Epub 2016 Jun 7.


Bayesian hierarchical modelling for inferring genetic interactions in yeast.

Heydari J, Lawless C, Lydall DA, Wilkinson DJ.

J R Stat Soc Ser C Appl Stat. 2016 Apr;65(3):367-393. Epub 2015 Oct 29.


APID interactomes: providing proteome-based interactomes with controlled quality for multiple species and derived networks.

Alonso-López D, Gutiérrez MA, Lopes KP, Prieto C, Santamaría R, De Las Rivas J.

Nucleic Acids Res. 2016 Jul 8;44(W1):W529-35. doi: 10.1093/nar/gkw363. Epub 2016 Apr 30.


Gene-nutrient interaction markedly influences yeast chronological lifespan.

Smith DL Jr, Maharrey CH, Carey CR, White RA, Hartman JL 4th.

Exp Gerontol. 2016 Dec 15;86:113-123. doi: 10.1016/j.exger.2016.04.012. Epub 2016 Apr 25.


Similarity analysis between chromosomes of Homo sapiens and monkeys with correlation coefficient, rank correlation coefficient and cosine similarity measures.

Someswara Rao C, Viswanadha Raju S.

Genom Data. 2016 Jan 7;7:202-9. doi: 10.1016/j.gdata.2016.01.001. eCollection 2016 Mar.


Intramolecular allosteric communication in dopamine D2 receptor revealed by evolutionary amino acid covariation.

Sung YM, Wilkins AD, Rodriguez GJ, Wensel TG, Lichtarge O.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3539-44. doi: 10.1073/pnas.1516579113. Epub 2016 Mar 15.


Combined Use of Gene Expression Modeling and siRNA Screening Identifies Genes and Pathways Which Enhance the Activity of Cisplatin When Added at No Effect Levels to Non-Small Cell Lung Cancer Cells In Vitro.

Leung AW, Hung SS, Backstrom I, Ricaurte D, Kwok B, Poon S, McKinney S, Segovia R, Rawji J, Qadir MA, Aparicio S, Stirling PC, Steidl C, Bally MB.

PLoS One. 2016 Mar 3;11(3):e0150675. doi: 10.1371/journal.pone.0150675. eCollection 2016.


A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions.

Sameith K, Amini S, Groot Koerkamp MJ, van Leenen D, Brok M, Brabers N, Lijnzaad P, van Hooff SR, Benschop JJ, Lenstra TL, Apweiler E, van Wageningen S, Snel B, Holstege FC, Kemmeren P.

BMC Biol. 2015 Dec 23;13:112. doi: 10.1186/s12915-015-0222-5.

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