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Ubiquitin Accumulation on Disease Associated Protein Aggregates Is Correlated with Nuclear Ubiquitin Depletion, Histone De-Ubiquitination and Impaired DNA Damage Response.

Ben Yehuda A, Risheq M, Novoplansky O, Bersuker K, Kopito RR, Goldberg M, Brandeis M.

PLoS One. 2017 Jan 4;12(1):e0169054. doi: 10.1371/journal.pone.0169054.


The ubiquitin hybrid gene UBA52 regulates ubiquitination of ribosome and sustains embryonic development.

Kobayashi M, Oshima S, Maeyashiki C, Nibe Y, Otsubo K, Matsuzawa Y, Nemoto Y, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Watanabe M.

Sci Rep. 2016 Nov 10;6:36780. doi: 10.1038/srep36780.


Nutritional conditions regulate transcriptional activity of SF-1 by controlling sumoylation and ubiquitination.

Lee J, Yang DJ, Lee S, Hammer GD, Kim KW, Elmquist JK.

Sci Rep. 2016 Jan 11;6:19143. doi: 10.1038/srep19143.


Cell Pluripotency Levels Associated with Imprinted Genes in Human.

Yuan L, Tang X, Zhang B, Ding G.

Comput Math Methods Med. 2015;2015:471076. doi: 10.1155/2015/471076.


Ubiquitin homeostasis: from neural stem cell differentiation to neuronal development.

Ryu HW, Ryu KY.

Neural Regen Res. 2015 Aug;10(8):1209-10. doi: 10.4103/1673-5374.162693. No abstract available.


Distinct effects of ubiquitin overexpression on NMJ structure and motor performance in mice expressing catalytically inactive USP14.

Vaden JH, Watson JA, Howard AD, Chen PC, Wilson JA, Wilson SM.

Front Mol Neurosci. 2015 Apr 23;8:11. doi: 10.3389/fnmol.2015.00011.


Hypothalamic miRNAs: emerging roles in energy balance control.

Schneeberger M, Gomez-Valadés AG, Ramirez S, Gomis R, Claret M.

Front Neurosci. 2015 Feb 12;9:41. doi: 10.3389/fnins.2015.00041. Review. Erratum in: Front Neurosci. 2015;9:96.


Cellular ubiquitin pool dynamics and homeostasis.

Park CW, Ryu KY.

BMB Rep. 2014 Sep;47(9):475-82. Review.


Deletion of miRNA processing enzyme Dicer in POMC-expressing cells leads to pituitary dysfunction, neurodegeneration and development of obesity.

Schneeberger M, Altirriba J, García A, Esteban Y, Castaño C, García-Lavandeira M, Alvarez CV, Gomis R, Claret M.

Mol Metab. 2012 Nov 12;2(2):74-85. doi: 10.1016/j.molmet.2012.10.001.


Neuronal ubiquitin homeostasis.

Hallengren J, Chen PC, Wilson SM.

Cell Biochem Biophys. 2013 Sep;67(1):67-73. doi: 10.1007/s12013-013-9634-4. Review.


β-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1.

Poon WW, Carlos AJ, Aguilar BL, Berchtold NC, Kawano CK, Zograbyan V, Yaopruke T, Shelanski M, Cotman CW.

J Biol Chem. 2013 Jun 7;288(23):16937-48. doi: 10.1074/jbc.M113.463711.


Neuroinflammation and neurodegeneration in overnutrition-induced diseases.

Cai D.

Trends Endocrinol Metab. 2013 Jan;24(1):40-7. doi: 10.1016/j.tem.2012.11.003. Review.


cAMP stimulates the ubiquitin/proteasome pathway in rat spinal cord neurons.

Myeku N, Wang H, Figueiredo-Pereira ME.

Neurosci Lett. 2012 Oct 11;527(2):126-31. doi: 10.1016/j.neulet.2012.08.051.


Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons.

Yang SB, Tien AC, Boddupalli G, Xu AW, Jan YN, Jan LY.

Neuron. 2012 Aug 9;75(3):425-36. doi: 10.1016/j.neuron.2012.03.043.


The fallacy of ratio correction to address confounding factors.

Karp NA, Segonds-Pichon A, Gerdin AK, Ramírez-Solis R, White JK.

Lab Anim. 2012 Jul;46(3):245-52. doi: 10.1258/la.2012.012003.


A bayesian translational framework for knowledge propagation, discovery, and integration under specific contexts.

Deng M, Zollanvari A, Alterovitz G.

AMIA Jt Summits Transl Sci Proc. 2012;2012:25-34.


Perturbation of the hematopoietic system during embryonic liver development due to disruption of polyubiquitin gene Ubc in mice.

Ryu KY, Park H, Rossi DJ, Weissman IL, Kopito RR.

PLoS One. 2012;7(2):e32956. doi: 10.1371/journal.pone.0032956.


Indirect inhibition of 26S proteasome activity in a cellular model of Huntington's disease.

Hipp MS, Patel CN, Bersuker K, Riley BE, Kaiser SE, Shaler TA, Brandeis M, Kopito RR.

J Cell Biol. 2012 Mar 5;196(5):573-87. doi: 10.1083/jcb.201110093.

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