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Items: 1 to 20 of 56

1.

Toward Personalized Gene Therapy: Characterizing the Host Genetic Control of Lentiviral-Vector-Mediated Hepatic Gene Delivery.

Suwanmanee T, Ferris MT, Hu P, Gui T, Montgomery SA, Pardo-Manuel de Villena F, Kafri T.

Mol Ther Methods Clin Dev. 2017 Apr 5;5:83-92. doi: 10.1016/j.omtm.2017.03.009. eCollection 2017 Jun 16.

2.

Retroviral integrase protein and intasome nucleoprotein complex structures.

Grawenhoff J, Engelman AN.

World J Biol Chem. 2017 Feb 26;8(1):32-44. doi: 10.4331/wjbc.v8.i1.32. Review.

3.

HIV-1 Vpr reactivates latent HIV-1 provirus by inducing depletion of class I HDACs on chromatin.

Romani B, Kamali Jamil R, Hamidi-Fard M, Rahimi P, Momen SB, Aghasadeghi MR, Allahbakhshi E.

Sci Rep. 2016 Aug 23;6:31924. doi: 10.1038/srep31924.

4.

HIV Genome-Wide Protein Associations: a Review of 30 Years of Research.

Li G, De Clercq E.

Microbiol Mol Biol Rev. 2016 Jun 29;80(3):679-731. doi: 10.1128/MMBR.00065-15. Print 2016 Sep. Review.

5.

The Structure-Specific Recognition Protein 1 Associates with Lens Epithelium-Derived Growth Factor Proteins and Modulates HIV-1 Replication.

Lopez AP, Kugelman JR, Garcia-Rivera J, Urias E, Salinas SA, Fernandez-Zapico ME, Llano M.

J Mol Biol. 2016 Jul 17;428(14):2814-31. doi: 10.1016/j.jmb.2016.05.013. Epub 2016 May 21.

6.
7.

Retroviral Integrase Structure and DNA Recombination Mechanism.

Engelman A, Cherepanov P.

Microbiol Spectr. 2014;2(6):1-22.

8.

TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism.

Fadel HJ, Morrison JH, Saenz DT, Fuchs JR, Kvaratskhelia M, Ekker SC, Poeschla EM.

J Virol. 2014 Sep 1;88(17):9704-17. doi: 10.1128/JVI.01397-14. Epub 2014 Jun 18.

9.

Preclinical profile of BI 224436, a novel HIV-1 non-catalytic-site integrase inhibitor.

Fenwick C, Amad M, Bailey MD, Bethell R, Bös M, Bonneau P, Cordingley M, Coulombe R, Duan J, Edwards P, Fader LD, Faucher AM, Garneau M, Jakalian A, Kawai S, Lamorte L, LaPlante S, Luo L, Mason S, Poupart MA, Rioux N, Schroeder P, Simoneau B, Tremblay S, Tsantrizos Y, Witvrouw M, Yoakim C.

Antimicrob Agents Chemother. 2014 Jun;58(6):3233-44. doi: 10.1128/AAC.02719-13. Epub 2014 Mar 24.

10.

Oncogenic human papillomaviruses activate the tumor-associated lens epithelial-derived growth factor (LEDGF) gene.

Leitz J, Reuschenbach M, Lohrey C, Honegger A, Accardi R, Tommasino M, Llano M, von Knebel Doeberitz M, Hoppe-Seyler K, Hoppe-Seyler F.

PLoS Pathog. 2014 Mar 6;10(3):e1003957. doi: 10.1371/journal.ppat.1003957. eCollection 2014 Mar.

11.

Multimodal mechanism of action of allosteric HIV-1 integrase inhibitors.

Jurado KA, Engelman A.

Expert Rev Mol Med. 2013 Nov 26;15:e14. doi: 10.1017/erm.2013.15. Review.

12.

Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells.

Balakrishnan M, Yant SR, Tsai L, O'Sullivan C, Bam RA, Tsai A, Niedziela-Majka A, Stray KM, Sakowicz R, Cihlar T.

PLoS One. 2013 Sep 9;8(9):e74163. doi: 10.1371/journal.pone.0074163. eCollection 2013.

13.

Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation.

Jurado KA, Wang H, Slaughter A, Feng L, Kessl JJ, Koh Y, Wang W, Ballandras-Colas A, Patel PA, Fuchs JR, Kvaratskhelia M, Engelman A.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8690-5. doi: 10.1073/pnas.1300703110. Epub 2013 Apr 22.

14.

Foamy virus assembly with emphasis on pol encapsidation.

Lee EG, Stenbak CR, Linial ML.

Viruses. 2013 Mar 20;5(3):886-900. doi: 10.3390/v5030886. Review.

15.

Epigenetic repression of LEDGF during UVB exposure by recruitment of SUV39H1 and HDAC1 to the Sp1-responsive elements within LEDGF promoter CpG island.

Bhargavan B, Chhunchha B, Fatma N, Kubo E, Kumar A, Singh DP.

Epigenetics. 2013 Mar;8(3):268-80. doi: 10.4161/epi.23861. Epub 2013 Feb 5.

16.

Identification of low molecular weight nuclear complexes containing integrase during the early stages of HIV-1 infection.

Gérard A, Soler N, Ségéral E, Belshan M, Emiliani S.

Retrovirology. 2013 Feb 1;10:13. doi: 10.1186/1742-4690-10-13.

17.

Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration.

Koh Y, Wu X, Ferris AL, Matreyek KA, Smith SJ, Lee K, KewalRamani VN, Hughes SH, Engelman A.

J Virol. 2013 Jan;87(1):648-58. doi: 10.1128/JVI.01148-12. Epub 2012 Oct 24.

18.

Retroviral integrase proteins and HIV-1 DNA integration.

Krishnan L, Engelman A.

J Biol Chem. 2012 Nov 30;287(49):40858-66. doi: 10.1074/jbc.R112.397760. Epub 2012 Oct 5. Review.

19.

HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor.

Wang H, Jurado KA, Wu X, Shun MC, Li X, Ferris AL, Smith SJ, Patel PA, Fuchs JR, Cherepanov P, Kvaratskhelia M, Hughes SH, Engelman A.

Nucleic Acids Res. 2012 Dec;40(22):11518-30. doi: 10.1093/nar/gks913. Epub 2012 Oct 5.

20.

The molecular biology of HIV integrase.

Craigie R.

Future Virol. 2012 Jul;7(7):679-686.

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