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Items: 1 to 20 of 97

1.

"Pumping iron"-how macrophages handle iron at the systemic, microenvironmental, and cellular levels.

Nairz M, Theurl I, Swirski FK, Weiss G.

Pflugers Arch. 2017 Apr;469(3-4):397-418. doi: 10.1007/s00424-017-1944-8. Epub 2017 Mar 1. Review.

2.

The Heme Connection: Linking Erythrocytes and Macrophage Biology.

Alam MZ, Devalaraja S, Haldar M.

Front Immunol. 2017 Jan 24;8:33. doi: 10.3389/fimmu.2017.00033. eCollection 2017. Review.

3.

Neomorphic effects of the neonatal anemia (Nan-Eklf) mutation contribute to deficits throughout development.

Planutis A, Xue L, Trainor CD, Dangeti M, Gillinder K, Siatecka M, Nebor D, Peters LL, Perkins AC, Bieker JJ.

Development. 2017 Feb 1;144(3):430-440. doi: 10.1242/dev.145656.

PMID:
28143845
4.

Mutations in the Heme Exporter FLVCR1 Cause Sensory Neurodegeneration with Loss of Pain Perception.

Chiabrando D, Castori M, di Rocco M, Ungelenk M, Gießelmann S, Di Capua M, Madeo A, Grammatico P, Bartsch S, Hübner CA, Altruda F, Silengo L, Tolosano E, Kurth I.

PLoS Genet. 2016 Dec 6;12(12):e1006461. doi: 10.1371/journal.pgen.1006461. eCollection 2016 Dec.

5.

Regulation of intracellular heme trafficking revealed by subcellular reporters.

Yuan X, Rietzschel N, Kwon H, Walter Nuno AB, Hanna DA, Phillips JD, Raven EL, Reddi AR, Hamza I.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5144-52. doi: 10.1073/pnas.1609865113. Epub 2016 Aug 15.

6.

Maternal iron status during pregnancy compared with neonatal iron status better predicts placental iron transporter expression in humans.

Best CM, Pressman EK, Cao C, Cooper E, Guillet R, Yost OL, Galati J, Kent TR, O'Brien KO.

FASEB J. 2016 Oct;30(10):3541-3550. Epub 2016 Jul 11.

PMID:
27402672
7.

Heme Oxygenase-1 and Carbon Monoxide in the Heart: The Balancing Act Between Danger Signaling and Pro-Survival.

Otterbein LE, Foresti R, Motterlini R.

Circ Res. 2016 Jun 10;118(12):1940-59. doi: 10.1161/CIRCRESAHA.116.306588. Review.

PMID:
27283533
8.

Heme dynamics and trafficking factors revealed by genetically encoded fluorescent heme sensors.

Hanna DA, Harvey RM, Martinez-Guzman O, Yuan X, Chandrasekharan B, Raju G, Outten FW, Hamza I, Reddi AR.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7539-44. doi: 10.1073/pnas.1523802113. Epub 2016 May 31.

9.

Delayed globin synthesis leads to excess heme and the macrocytic anemia of Diamond Blackfan anemia and del(5q) myelodysplastic syndrome.

Yang Z, Keel SB, Shimamura A, Liu L, Gerds AT, Li HY, Wood BL, Scott BL, Abkowitz JL.

Sci Transl Med. 2016 May 11;8(338):338ra67. doi: 10.1126/scitranslmed.aaf3006.

10.

Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop a Defect in Erythropoiesis.

Kamio T, Gu BW, Olson TS, Zhang Y, Mason PJ, Bessler M.

PLoS One. 2016 Apr 4;11(4):e0152263. doi: 10.1371/journal.pone.0152263. eCollection 2016.

11.

TLR Stimulation Dynamically Regulates Heme and Iron Export Gene Expression in Macrophages.

Philip M, Chiu EY, Hajjar AM, Abkowitz JL.

J Immunol Res. 2016;2016:4039038. doi: 10.1155/2016/4039038. Epub 2016 Feb 24.

12.

Iron Homeostasis in Health and Disease.

Gozzelino R, Arosio P.

Int J Mol Sci. 2016 Jan 20;17(1). pii: E130. doi: 10.3390/ijms17010130. Review.

13.

Mechanism governing heme synthesis reveals a GATA factor/heme circuit that controls differentiation.

Tanimura N, Miller E, Igarashi K, Yang D, Burstyn JN, Dewey CN, Bresnick EH.

EMBO Rep. 2016 Feb;17(2):249-65. doi: 10.15252/embr.201541465. Epub 2015 Dec 23.

14.

Biology of Heme in Mammalian Erythroid Cells and Related Disorders.

Fujiwara T, Harigae H.

Biomed Res Int. 2015;2015:278536. doi: 10.1155/2015/278536. Epub 2015 Oct 18. Review.

15.

Coordinate expression of heme and globin is essential for effective erythropoiesis.

Doty RT, Phelps SR, Shadle C, Sanchez-Bonilla M, Keel SB, Abkowitz JL.

J Clin Invest. 2015 Dec;125(12):4681-91. doi: 10.1172/JCI83054. Epub 2015 Nov 9.

16.

ATP Binding Cassette Transporter Mediates Both Heme and Pesticide Detoxification in Tick Midgut Cells.

Lara FA, Pohl PC, Gandara AC, Ferreira Jda S, Nascimento-Silva MC, Bechara GH, Sorgine MH, Almeida IC, Vaz Ida S Jr, Oliveira PL.

PLoS One. 2015 Aug 10;10(8):e0134779. doi: 10.1371/journal.pone.0134779. eCollection 2015.

17.

Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury.

Sawicki KT, Shang M, Wu R, Chang HC, Khechaduri A, Sato T, Kamide C, Liu T, Naga Prasad SV, Ardehali H.

J Am Heart Assoc. 2015 Jul 31;4(8):e002272. doi: 10.1161/JAHA.115.002272.

18.

The ins and outs of erythroid heme transport.

Cao C, Fleming MD.

Haematologica. 2015 Jun;100(6):703. doi: 10.3324/haematol.2015.127886. No abstract available.

19.

The heme exporter Flvcr1 regulates expansion and differentiation of committed erythroid progenitors by controlling intracellular heme accumulation.

Mercurio S, Petrillo S, Chiabrando D, Bassi ZI, Gays D, Camporeale A, Vacaru A, Miniscalco B, Valperga G, Silengo L, Altruda F, Baron MH, Santoro MM, Tolosano E.

Haematologica. 2015 Jun;100(6):720-9. doi: 10.3324/haematol.2014.114488. Epub 2015 Mar 20.

20.

Macrophages and iron trafficking at the birth and death of red cells.

Korolnek T, Hamza I.

Blood. 2015 May 7;125(19):2893-7. doi: 10.1182/blood-2014-12-567776. Epub 2015 Mar 16. Review.

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